IL-6 Protein, Pig HY-P73220 from MedChemExpress

Description

IL-6 protein is a multifunctional cytokine that participates in immune, regenerative and metabolic processes by binding to IL6R and forming a complex with IL6ST/gp130. This activates the IL6 signaling pathway, initiating 'classical signaling' via membrane-bound IL6R and IL6ST, 'trans signaling' via binding of IL6 and soluble IL6R to IL6ST, and 'cluster signaling' via the IL6:IL6R complex '. IL-6 Protein, Pig is the recombinant pig-derived IL-6 protein, expressed by E. coli, with tag free

Product Specs
ItemIL-6 Protein, Pig
CompanyMedChemExpress
Price $440.00Supplier Page View Company Product Page
Catalog NumberHY-P73220
SpeciesPig
Activity1.Measured by its binding ability in a functional ELISA. Immobilized sus scrofa (pig) IL6 at 2 µg/mL (100 µl/well) can bind Human IL-6R-His, the EC₅₀ of Human IL-6R-His is 250-750 ng/mL.
2. Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED₅₀ for this effect is typically 1-5 ng/mL
Source/Expression SystemE. coli
Molecular WeightApproximately 21.2 kDa
Size50 µg
TypeProtein
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting