PDGF-BB Protein, Human HY-P7055 from MedChemExpress

Product Specs
ItemPDGF-BB Protein, Human
CompanyMedChemExpress
Price $590.00Supplier Page View Company Product Page
Catalog NumberHY-P7055
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
TypeProtein
Size50 µg
Molecular WeightApproximately 24.8 kDa
Source/Expression SystemE. coli
ActivityThe ED₅₀ is <3 ng/mL as measured by murine Balb/c 3T3 cells, corresponding to a specific activity of >3.3 × 10⁵ units/mg
SpeciesHuman
NCBI Full Gene Nameplatelet derived growth factor subunit B
NCBI Gene AliasesSIS, IBGC5, c-sis, SSV, PDGF-2, PDGF2

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(1) Salvia miltiorrhiza-derived microRNA58 inhibits tumor growth by targeting Krüppel-like factor 3 in human endothelial cellsTranslational Cancer ResearchFebruary 28, 2026Yan Qin, Minghui Zhao, Jingxin Zhang, Yuhe Pei, Siyuan Suo, Min Wu, Yan Shi, Feixiang Wu, Zhou Shen, Hao Li, et al.used in all of the experiments. Before stimulation with 10 ng/mL of PDGF-BB (MedChemExpress, cat. No. HY-P7055; Monmouth, NJ, USA), 1×106 cells/well were incubated in serum-free medium for 24 h. The human embryonic

(2) Single-cell transcriptomics identifies PDGFRA+ progenitors orchestrating angiogenesis and periodontal tissue regenerationInt J Oral SciJuly 24, 2025Jianing Liu, Junxi He, Ziqi Zhang, Lu Liu, Yuan Cao, Xiaohui Zhang, Xinyue Cai, Xinyan Luo, Xiao Lei, Nan Zhang, et al.involving DFSCs treated with PDGFBB were conducted by supplementing the culture medium with PDGFBB (HY-P7055, MCE, China) at a concentration of 100 ng/mL when the cell confluence reached 40%-50%. After 48 h, conditioned

(3) Long Non‐Coding RNA IGFRIL Couples with PTBP1 to Destabilize IGFBP3 mRNA to Promote the IGF1R‐AKT‐mTOR Axis and Hepatocellular CarcinomaAdvanced ScienceJuly 21, 2025Jing Zhang, Chengming Gao, Haibei Li, Yuying Chen, Liting Yang, Qian Jin, Lan Feng, Xia Wang, Xinyi Liu, Hongxia Chen, et al.C032, Novoprotein, China), insulin (100 ng mL−1; HY‐P73243, MedChemExpress, USA), PDGF (100 ng mL−1; HY‐P7055, MedChemExpress, USA), EGF (100 ng mL−1; HY‐P7109, MedChemExpress, USA) or FGF2 (100 ng mL−1; HY‐P7004,

(4) The Multitarget Compound ZLY032 Achieves Treatment of Chronic WoundsAdvanced ScienceJuly 17, 2025Manyu Gong, Zhiyuan Du, Tiantian Gong, Yu Wang, Chenchen Yin, Bosi Sun, Zijia Liu, Lianru Chen, Zibin Liao, Wenxin Wang, et al.and Topical Application of PDGF and Penicillin G on Wound PDGF purchased from MedChemExpress (Cat#HY‐P7055, MCE, USA) was added into the PBS solution, which containing 0.1% DMSO, and the final concentration

(5) Hydrogen Sulfide Promotes Platelet Autophagy via PDGFR-α/PI3K/Akt Signaling in Cirrhotic ThrombocytopeniaJournal of Clinical and Translational HepatologyJuly 28, 2024Hua-Xiang Yang, Yang-Jie Li, Yang-Lan He, Ke-Ke Jin, Ling-Na Lyu, Hui-Guo Dingplatelets (1.0×109/mL) were incubated with NaHS (Sigma-Aldrich, 161527-100G), PDGF-BB (MedChemExpress, HY-P7055), hydroxycobalamin (MedChemExpress, HY-B2209), AG 1295 (MedChemExpress, HY-101957), respectively, or

(6) Mechanism of acacetin regulating hepatic stellate cell apoptosis based on network pharmacology and experimental verificationHeliyonApril 15, 2024Xue Hu, Haotian Shen, Rong Liu, Bin Tang, Fengmei DengMedChemExpress (No: HY-N0451), and Platelet-derived growth factor-BB (PDGF-BB) (MedChemExpress, No: HY-P7055) was purchased from Novus PDGF-BB, as the activator of HSCs, mimics the liver fibrosis microenvironment

(7) S-propargyl-cysteine promotes the stability of atherosclerotic plaque via maintaining vascular muscle contractile phenotypeFrontiers in Cell and Developmental BiologyJanuary 24, 2024Li Ping, Li Zhi-Ming, Zhang Bi-Shan, Zhu Lei, Yu Bo, Zhu Yi-Chun, Wang Ming-JiePDGF-BB group and the PDGF-BB + SPRC group. The last two groups were treated with 50 ng/mL PDGF-BB (HY-P7055, MCE, China) for 24 h. Cells were pre-incubated with 100 μM SPRC for 6 h before PDGF-BB treatment in

(8) PDGF-BB prevents destructive repair and promotes reparative osteogenesis of steroid-associated osteonecrosis of the femoral head in rabbitsBoneFebruary 1, 2023Cao H, Shi K, Long J, Liu Y, Li L, Ye T, Huang C, Lai Y, Bai X, Qin L, et al.

(9) Metabolomics of clinical samples reveal the treatment mechanism of lanthanum hydroxide on vascular calcification in chronic kidney diseaseProceedings of the Japan Academy. Series B, Physical and biological sciencesJanuary 1, 2022Gu C, Gao Y, Han R, Guo M, Liu H, Gao J, Liu Y, Li B, Sun L, Bu R, et al.#298182), PPI (Sigma-Aldrich, Cat. #S6422), PDGF-BB (MedChemExpress, Monmouth Junction, NJ, U.S.A., Cat. #HY-P7055), DMOG (Sigma-Aldrich, Cat. #400091), phosphatase inhibitor (P1082, Beyotime, Shanghai, China), RIPA

(10) Inhibition of PDGF-BB reduces alkali-induced corneal neovascularization in miceMolecular medicine reportsApril 1, 2021Chen L, Wu H, Ren C, Liu G, Zhang W, Liu W, Lu P.

(11) BOP1 Knockdown Attenuates Neointimal Hyperplasia by Activating p53 and Inhibiting Nascent Protein SynthesisOxidative medicine and cellular longevityJanuary 1, 2021Jia F, Wu Q, Wang Z, Zhang M, Yuan S, Che Y, Li B, Hu Z, Hu X.resuspended and cotreated with 20 ng/ml platelet-derived growth factor-BB (PDGF-BB; MedChemExpress, # HY-P7055, China). The ability of cell migration was evaluated via wound healing assay as our previous described

(12) Platelet-Derived Growth Factor-BB Inhibits Intervertebral Disc Degeneration via Suppressing Pyroptosis and Activating the MAPK Signaling PathwayFrontiers in pharmacologyJanuary 1, 2021Zhang W, Gong Y, Zheng X, Qiu J, Jiang T, Chen L, Lu F, Wu X, Cheng F, Hong Z.Reagents RHu PDGF-BB, IL-1β and imatinib mesylate were purchased from MedChemExpress, United States (cat. nos. HY-P7055; HY-P7097; HY-50946); PDGF-BB polyclonal antibody, collagen II monoclonal antibody and aggrecan neo

(13) Recombinant human platelet-derived growth factor-BB versus autologous bone graft in foot and ankle fusion: A systematic review and meta-analysisFoot and ankle surgery : official journal of the European Society of Foot and Ankle SurgeonsMarch 1, 2017Sun H, Lu PP, Zhou PH, Sun SW, Zhang HT, Liu YJ, Yang X, Shen XF, Yang HL.

(14) Comparison of the effect of intra-tendon applications of recombinant human platelet-derived growth factor-BB, platelet-rich plasma, steroids in a rat achilles tendon collagenase modelJournal of orthopaedic research : official publication of the Orthopaedic Research SocietyJanuary 1, 2014Solchaga LA, Bendele A, Shah V, Snel LB, Kestler HK, Dines JS, Hee CK.

(15) PDGF-BB does not accelerate healing in diabetic mice with splinted skin woundsPloS oneJanuary 1, 2014Park SA, Raghunathan VK, Shah NM, Teixeira L, Motta MJ, Covert J, Dubielzig R, Schurr M, Isseroff RR, Abbott NL, et al.

(16) Paradoxical effects of PDGF-BB overexpression in endothelial cells on engineered blood vessels in vivoThe American journal of pathologyJuly 1, 2009Au P, Tam J, Duda DG, Lin PC, Munn LL, Fukumura D, Jain RK.

(17) Potential roles of growth factor PDGF-BB in the bony repair of injured growth plateBoneMay 1, 2009Chung R, Foster BK, Zannettino AC, Xian CJ.

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PDGF-BB Protein, Human from MedChemExpress

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PDGF-BB Protein, Human from MedChemExpress

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