Substance P HY-P0201 from MedChemExpress

Product Specs
ItemSubstance P
CompanyMedChemExpress
Price $66.00Supplier Page View Company Product Page
Catalog NumberHY-P0201
Size1 mg
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.82%
TypeChemical
Molecular Weight1347.63
FormulaC₆₃H₉₈N₁₈O₁₃S
Research AreaNeurological Disease; Endocrinology; Cancer

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(1) Palmitic acid aggravates atopic dermatitis by regulating SGK1/NEDD4L-involved cutaneous neuroimmune inflammation through driving TRPV1 and MRGPRB2 S-palmitoylationInflammation research : official journal of the European Histamine Research Society ... [et al.]February 2, 2026Chen B, Yang J, Song T, Wu W, Hao F, Yang Z.± 5%, light/dark:12 h/12 h) in specified pathogen free room. Reagents MC903(#HY-10001, MCE), SP(# HY-P0201, MCE), PA(#HY-N0830, MCE), 2-Bromopalmitate (2BP; #21604, Sigma-Aldrich), capsazepine (#HY-15640,MCE),

(2) Mast Cells Inhibit Stem Cell-driven Epithelial Repair in Inflammatory Bowel Disease via Suppressing Wnt/lrp6/β-Catenin Signaling PathwayCellular and Molecular Gastroenterology and HepatologyJanuary 29, 2026Tao Zhang, Jindong Zhang, Jingxian Xu, Xiaoang Li, Fei Pei, Liping Duan13). To mimic the pathological environment of colitis, MCs were activated with 50 μM substance P (MCE, HY-P0201), based on the established role of substance P-dependent MC activation in colitis.50 Organoid Construction

(3) Sensory-neuron-derived CGRPα controls white adipocyte differentiation and tissue plasticityCell ReportsDecember 23, 2025Kyle D. Dumont, Saba Heydari Heydari Seradj, Yu Wang, Shanshan Liu, Igor Cervenka, Chao Wu, Paulo R. Jannig, Margareta Porsmyr-Palmertz, Gerard Baiges-Gaya, Xun Huang, et al.with 100 nM of CGRPα (Bachem, 4025897 or MedChemExpress, HY-P0203), substance P (SP; MedChemExpress, HY-P0201), neuropeptide Y (NPY; MedChemExpress, HY-P0198), or norepinephrine (NE; Sigma, A7256) during the differentiation

(4) The role of substance P in Th17/Treg imbalance and ocular surface damage in chronic allergic conjunctivitisJ Transl MedDecember 1, 2025Jiayu Bao, Ya Wen, Binge Wu, Yaqiong Li, Siyuan Li, Fengyang Lei, Lei Tian, Xiaoniao Chen, Ying Jiegroup, n = 20), the control group (PBS group, n = 20), the secondary OVA sensitization group + SP (HY-P0201, MedChemExpress) treatment (2°OVA + SP group, n = 20), and the secondary OVA sensitization group + SP/NK-1R

(5) Clinical impact of collagen sponge combined with substance P on maxillofacial trauma repair in ratsFrontiers in MedicineOctober 16, 2025Qian Wang, Yong Zhang, Yan Guo, Xiaolan Yangmaxillofacial trauma was treated with Vaseline gauze of the same size as the wound and sprayed with SP (10−7 M, HY-P0201, MedChemExpress, United States) every 6 h. In RG 2, maxillofacial trauma was filled with a collagen

(6) Clinical impact of collagen sponge combined with substance P on maxillofacial trauma repair in ratsFront Med (Lausanne)October 16, 2025Qian Wang, Yong Zhang, Yan Guo, Xiaolan Yangmaxillofacial trauma was treated with Vaseline gauze of the same size as the wound and sprayed with SP (10−7 M, HY-P0201, MedChemExpress, United States) every 6 h. In RG 2, maxillofacial trauma was filled with a collagen

(7) Comparison of gepant effects at therapeutic plasma concentrations: connecting pharmacodynamics and pharmacokineticsThe Journal of Headache and PainAugust 28, 2024Deirdre M. Boucherie, Ruben Dammers, Arnaud Vincent, A. H. Jan Danser, Antoinette MaassenVanDenBrinklogarithmic steps). After thorough washing, endothelial function was assessed with substance P (MCE, HY-P0201; 10 – 100 nM) after precontraction with U46619 (Sigma-Aldrich, D8174; 10 – 100 nM). CGRP-induced relaxation

(8) Trigeminal nerve-derived substance P regulates limbal stem cells by the PI3K-AKT pathwayiScienceMay 19, 2023Xu P, Lin X, Dong X, Liu Y, Wang Z, Wang S.photographed by a slit lamp (TOPCON, Tokyo, Japan). For topical SP application, 5 μL SP (1 mM, Cat # HY-P0201, MedChemExpress) was dropped on the corneal surface of each eye six times daily for 3 days after the

(9) MiR-34b/c-5p and the neurokinin-1 receptor regulate breast cancer cell proliferation and apoptosisCell proliferationJanuary 1, 2019Zhang L, Wang L, Dong D, Wang Z, Ji W, Yu M, Zhang F, Niu R, Zhou Y.

(10) Delineation of the endocytic pathway of substance P and its seven-transmembrane domain NK1 receptorMolecular biology of the cellMay 1, 1995Grady EF, Garland AM, Gamp PD, Lovett M, Payan DG, Bunnett NW.

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Substance P from MedChemExpress

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Substance P from MedChemExpress

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