NFAT Inhibitor-1 HY-P1026 from MedChemExpress

Product Specs
ItemNFAT Inhibitor-1
CompanyMedChemExpress
Price $92.00Supplier Page View Company Product Page
Catalog NumberHY-P1026
Size1 mg
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity98.03%
TypeChemical
Molecular Weight1685.94
FormulaC₇₅H₁₂₀N₂₀O₂₂S
Research AreaInflammation/Immunology

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(1) NFAT1 Signaling Contributes to Bone Cancer Pain by Regulating IL-18 Expression in Spinal MicrogliaCNS Neurosci TherFebruary 17, 2025Xuetai Chen, Ying Zeng, Zizhu Wang, Jixiang Zhu, Fengyun Liu, Mingxuan Zhu, Jiayi Zheng, Qingdaiyao Chen, Dongxu Zhai, Yangyang Chen, et al.sterile bone wax to prevent cell leakage. 2.4 Drugs and Administration The NFAT1 inhibitor 11R‐VIVIT (HY‐P1026) and p38 MAPK inhibitor SB239063 (HY‐11068) were purchased from MedChemExpress (USA). IL‐18 binding

(2) Basic-helix-loop-helix family member e41 suppresses osteoclastogenesis and abnormal bone resorption disease via NFATc1iScienceMarch 15, 2024Yufeng Zhang, Xiaoguang Li, Jianlong Lang, Wenbo Li, Dengke Huang, Weizong Sun, Li Yang, Wenhui Li, Yi Wang, Liang Zhanginverted microscope system (Olympus, IX73). NFATc1 was inhibited with 10μM NFAT Inhibitor (MCE, Cat#HY-P1026). Animal experiments To establish an osteoporosis mouse model,44 8-week-old C57BL/6 female mice were

(3) Meniscal fibrocartilage regeneration inspired by meniscal maturational and regenerative processScience AdvancesNovember 10, 2023Wenqiang Yan, Maihemuti Maimaitimin, Yue Wu, Yifei Fan, Shuang Ren, Fengyuan Zhao, Chenxi Cao, Xiaoqing Hu, Jin Cheng, Yingfang Aofor 4 hours. To suppress NFATc1, human SMSCs were treated with 10 μM NFAT inhibitor (VIVIT peptide, HY-P1026, MCE) for 4 hours. To evaluate the effect of substrate rigidity on human SMSCs phenotypes, the traditional

(4) Gsmtx4 Alleviated Osteoarthritis through Piezo1/Calcineurin/NFAT1 Signaling Axis under Excessive Mechanical StrainInternational journal of molecular sciencesFebruary 16, 2023Ren X, Zhuang H, Li B, Jiang F, Zhang Y, Zhou P.NC, USA) [48]. For pharmacological interventions, Gsmtx4 (40 μM) [23], NFAT inhibitor-1 VIVIT (10 μM, HY-P1026, MCE, Shanghai, China) [24], Cyclosporin A (1 μM, HY-B0579, MCE, Shanghai, China) [15], and Yoda1 (5

(5) PROSER2 is a poor prognostic biomarker for patients with osteosarcoma and promotes proliferation, migration and invasion of osteosarcoma cellsExperimental and therapeutic medicineDecember 1, 2022Li Z, Zhang Y, Li Y, Xing S, Li S, Lyu J, Ban Z.Scientific, Inc.). MTT was obtained from Sigma-Aldrich (Merck KGaA). The NFAT inhibitor VIVIT (cat. no. HY-P1026) was obtained from MedChemExpress. Clinical specimens collected from the Orthopedics Department at Chengdu

(6) BHLHE40 promotes osteoclastogenesis and abnormal bone resorption via c-Fos/NFATc1Cell & bioscienceMay 26, 2022Zhang Y, Yang M, Zhang S, Yang Z, Zhu Y, Wang Y, Chen Z, Lv X, Huang Z, Xie Y, et al.Statistics are based on the number of OCs in 8 fields. For drug experiments, 10 µM NFAT Inhibitor (MCE, Cat# HY-P1026) was used to inhibit NFATc1, and 10 µM T-5224 (MCE, Cat# HY-12270) was used to inhibit c-Fos. Isolation,

(7) Fusobacterium nucleatum Promotes Cisplatin-Resistance and Migration of Oral Squamous Carcinoma Cells by Up-Regulating Wnt5a-Mediated NFATc3 ExpressionThe Tohoku journal of experimental medicineApril 1, 2021Da J, Wang X, Li L, Xu Y.including CCK-8 and western blotting of E-cadherin and apoptosis-related proteins with NFATinhibitor VIVIT (HY-P1026; MedChemExpress, New Jersey, USA). It is a cell-permeable peptide inhibitor of NFAT that selectively

(8) Activation of the Peroxisome Proliferator-Activated Receptor γ Coactivator 1β/NFATc1 Pathway in Circulating Osteoclast Precursors Associated With Bone Destruction in Rheumatoid ArthritisArthritis & rheumatology (Hoboken, N.J.)August 1, 2019Ma JD, Jing J, Wang JW, Mo YQ, Li QH, Lin JZ, Chen LF, Shao L, Miossec P, Dai L.

(9) Affinity-driven peptide selection of an NFAT inhibitor more selective than cyclosporin AScience (New York, N.Y.)September 24, 1999Aramburu J, Yaffe MB, López-Rodríguez C, Cantley LC, Hogan PG, Rao A.

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NFAT Inhibitor-1 from MedChemExpress

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