Noggin Protein, Mouse (CHO) HY-P7086 from MedChemExpress

Description

Noggin protein is an important BMP inhibitor that plays an indispensable role in the neural tube, somite growth, cartilage morphogenesis, and joint formation. Its homodimeric structure promotes significant interactions with GDF5 and possibly GDF6, inhibiting chondrocyte differentiation. Noggin Protein, Mouse (CHO) is the recombinant mouse-derived Noggin protein, expressed in CHO

Product Specs
ItemNoggin Protein, Mouse (CHO)
CompanyMedChemExpress
Price $300.00Supplier Page View Company Product Page
Catalog NumberHY-P7086
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
TypeProtein
Size50 µg
Molecular Weight29-31 kDa
Source/Expression SystemCHO
ActivityThe ED₅₀ is <60 ng/mL as measured by ATDC5 cells
SpeciesMouse
NCBI Full Gene Namenoggin

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(1) CDK5RAP3 Regulates Testosterone Production in Mouse Leydig CellsInternational Journal of Molecular SciencesJanuary 6, 2026Jian Ruan, Qianyi Dong, Yufan Jin, Yuhong Yang, Jun Li, Yafei CaiAnti-Rabbit IgG (Cat#: BL003A) from Biosharp (Hefei, China). The following reagents were used: Noggin (Cat#: HY-P7086) and EDS (Cat#: HY-129524) from MCE (Shanghai, China); hCG (Cat#: H20052130) from Livzon (Zhuhai, China);

(2) Juglans regia L. extract promotes osteogenesis of human bone marrow mesenchymal stem cells through BMP2/Smad/Runx2 and Wnt/β-catenin pathwaysJournal of orthopaedic surgery and researchFebruary 14, 2022Pang X, Zhong Z, Jiang F, Yang J, Nie H.and OIM cultured group; OIM, JRL extract and 100 ng/mL BMP-inhibitory protein Noggin (MedChemExpress, HY-P7086) cultured group; OIM, LRL extract and 2 mg/mL Wnt antagonist Dickkopf-1 (DKK1, MedChemExpress, HY-P73513)

(3) An Automated Organoid Platform with Inter-organoid Homogeneity and Inter-patient HeterogeneityCell Reports MedicineDecember 22, 2020Shengwei Jiang et al.N0636 N-Acetylcysteine,Sigma-Aldrich,Cat# A9165 Noggin (Human),MCE,Cat# HY-P7051A Noggin (Mouse),MCE,Cat# HY-P7086 R-spondin 1,MCE,Cat# HY-P7114 SB431542,MCE,Cat# HY-10431 CHIR99021,MCE,Cat# HY-10182 FGF4,MCE,Cat#

(4) BMP inhibition enhances axonal growth and functional recovery after spinal cord injuryJournal of neurochemistryMay 1, 2008Matsuura I, Taniguchi J, Hata K, Saeki N, Yamashita T.

(5) The role of noggin in human mesenchymal stem cell differentiationJournal of cellular biochemistryMarch 1, 2007Rifas L.

(6) Structural basis of BMP signalling inhibition by the cystine knot protein NogginNatureDecember 12, 2002Groppe J, Greenwald J, Wiater E, Rodriguez-Leon J, Economides AN, Kwiatkowski W, Affolter M, Vale WW, Izpisua Belmonte JC, Choe S.

(7) Noggin, cartilage morphogenesis, and joint formation in the mammalian skeletonScience (New York, N.Y.)May 29, 1998Brunet LJ, McMahon JA, McMahon AP, Harland RM.

(8) Identification of mammalian noggin and its expression in the adult nervous systemThe Journal of neuroscience : the official journal of the Society for NeuroscienceSeptember 1, 1995Valenzuela DM, Economides AN, Rojas E, Lamb TM, Nuñez L, Jones P, Lp NY, Espinosa R 3rd, Brannan CI, Gilbert DJ.

(9) Secreted noggin protein mimics the Spemann organizer in dorsalizing Xenopus mesodermNatureFebruary 11, 1993Smith WC, Knecht AK, Wu M, Harland RM.

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Noggin Protein, Mouse (CHO) from MedChemExpress

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Noggin Protein, Mouse (CHO) from MedChemExpress

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