Complement C3/C3a Protein, Human HY-P7862 from MedChemExpress

Product Specs
ItemComplement C3/C3a Protein, Human
CompanyMedChemExpress
Price $250.00Supplier Page View Company Product Page
Catalog NumberHY-P7862
Size50 µg
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
TypeProtein
Molecular WeightApproximately 13.0 kDa
SpeciesHuman
Source/Expression SystemE. coli
NCBI Full Gene Namecomplement C3
NCBI Gene AliasesCPAMD1, HEL-S-62p, ASP, ARMD9, C3a, C3b, AHUS5

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(1) Age‐Related Complement C3 Drives Memory Impairments and Associated Neuropathologies in a Mouse ModelAging CellSeptember 1, 2025Miaomiao Du, Yujia Wang, Xinyuan Wang, Yifei Liu, Fuchuan Xiao, Jing Zhang, Xia Meng, Kunhe Ma, Na Wu, Baian Chen, et al.with 5% CO2 for 24 h. The medium was then replaced with fresh medium containing either 200 nM C3a (HY‐P7862, MCE, USA), a C3aR competitive antagonists (SB290157, HY‐101502A, MCE), or the respective control medium.

(2) Exploring the Role of TRAF6-TAK1 Pathway in Podocyte Pyroptosis and Its Implications for Primary Membranous Nephropathy TherapyInflammationJanuary 30, 2025Yaling Guo, Jingliang Min, Baochao Chang, Zheng Chen, Weidong ChenBeyotime) was added at a 1:100 ratio to the standard culture medium. Podocytes were treated with 50 nM C3a (HY-P7862, MCE) for 1 h to establish a complement-induced podocyte injury model (PMN group) [24, 25]. Commercial

(3) The complement C3a/C3aR pathway is associated with treatment resistance to gemcitabine-based neoadjuvant therapy in pancreatic cancerComputational and structural biotechnology journalDecember 1, 2024Shi S, Ye L, Jin K, Yu X, Guo D, Wu W.5′-CCAGTGTCCTTGGAGAATCAGG-3′;. 2.16 Chemical and protein reagents Recombinant human complement C3a protein (MedChemExpress, MCE; HY-P7862), recombinant mouse complement C3a protein (MCE; HY-P7863) and C3aR antagonist, SB290157 (TargetMol)

(4) Complement protein C3a enhances adaptive immune responses towards FVIII productsHaematologicaJune 1, 2023Ringler E, Iannazzo SO, Herzig J, Weiss LM, Anzaghe M, Miller L, Waibler Z.

(5) Complement C3a and C3a Receptor Activation Mediates Podocyte Injuries in the Mechanism of Primary Membranous NephropathyJournal of the American Society of Nephrology : JASNSeptember 1, 2022Gao S, Cui Z, Zhao MH.

(6) Complement component 3 protects human bronchial epithelial cells from cigarette smoke-induced oxidative stress and prevents incessant apoptosisFrontiers in immunologyJanuary 1, 2022Pei Y, Zhang J, Qu J, Rao Y, Li D, Gai X, Chen Y, Liang Y, Sun Y.

(7) Complement component C3a plays a critical role in endothelial activation and leukocyte recruitment into the brainJournal of neuroinflammationJanuary 28, 2016Wu F, Zou Q, Ding X, Shi D, Zhu X, Hu W, Liu L, Zhou H.

(8) Is the complement activation product C3a a proinflammatory molecule? Re-evaluating the evidence and the mythJournal of immunology (Baltimore, Md. : 1950)April 15, 2015Coulthard LG, Woodruff TM.

(9) Differential effects of complement activation products c3a and c5a on cardiovascular function in hypertensive pregnant ratsThe Journal of pharmacology and experimental therapeuticsNovember 1, 2014Lillegard KE, Loeks-Johnson AC, Opacich JW, Peterson JM, Bauer AJ, Elmquist BJ, Regal RR, Gilbert JS, Regal JF.

(10) Complement and coagulation: strangers or partners in crime?Trends in immunologyApril 1, 2007Markiewski MM, Nilsson B, Ekdahl KN, Mollnes TE, Lambris JD.

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Complement C3/C3a Protein, Human from MedChemExpress

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Complement C3/C3a Protein, Human from MedChemExpress

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