Noggin Protein, Human (CHO) HY-P7051A from MedChemExpress

Product Specs
ItemNoggin Protein, Human (CHO)
CompanyMedChemExpress
Price $120.00Supplier Page View Company Product Page
Catalog NumberHY-P7051A
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
TypeProtein
Size10 µg
Molecular Weight29-31 kDa
Source/Expression SystemCHO
Activity1.ED50 < 2.5 ng/ml, measured in a bioassay using ATDC5 cells in the presence of 10.0 ng/ml human BMP-4.
2.Measured by its ability to inhibit BMP-2-induced alkaline phosphatase production by ATDC5 mouse chondrogenic cells The ED₅₀ for this effect is < 420 ng/mL in the presence of 2000 ng/mL of Recombinant Human BMP-2
SpeciesHuman
NCBI Full Gene Namenoggin
NCBI Gene AliasesSYNS1A, SYM1, SYNS1

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(1) Reconstituting the head and neck tumor microenvironment with air-liquid interface organoidsFrontiers in OncologyJanuary 2, 2026Luxi Zheng, Wei Tang, Shuqi Guo, Lin Chen, Shoupeng Wang, Feng Liu, Jian MengI-A,CAT#: 637-00653,FUJIFILM Wako Pure Chemical Corporation Recombinant human noggin protein,CAT#: HY-P7051A,MCE Corporation Recombinant human R spodin-1 protein,CAT#: HY-P72784,MCE Corporation Recombinant human

(2) Understanding of the different roles of Noggin in the Noggin-BMP-2 and Noggin-BMP-9 dimer complexes at the molecular levelScientific ReportsJanuary 2, 2026Suhyun Park, Dong Woo Lee, Min-Ho Park, Jue Yeon Lee, Dakshinamurthy Sivakumar, Sathishkumar Mudedla, Yeon Gyo Seo, Sangwook Wu, Yoon Jeong Park, Chong Pyung Chung100 mm plate(Nunc, 150464) and pretreated with 2 nM recombinant human Noggin protein (MedChemExpress, HY-P7051A) in α-MEM (Welgene, LM008-01) medium for 30 min, followed by 8 nM BMP-2 (PeproTech, 120–02 C-10UG) or

(3) The Establishment of 3D Polarity-Reversed Organoids From Human Endometrial Tissue as a Model for Infection-Induced EndometritisBIO-PROTOCOLJune 20, 2025Xin Zhang, Li Zhang, Linyuan Fan, Zhaohui Liucatalog number: HY-P7109) 10. Rspondin-1 (MCE, catalog number: HY-P7114) 11. Noggin (MCE, catalog number: HY-P7051A) 12. Dimethyl sulfoxide (DMSO) (Sigma, catalog number: D2650) 13. TrypLE Express (Gibco, catalog number:

(4) Comparative analysis of organoid, air-liquid interface, and direct infection models for studying pathogen-host interactions in endometrial tissueSci RepMarch 12, 2025Xin Zhang, Linyuan Fan, Li Zhang, Zhaohui LiuHY-10432), 250 µg/mL EGF (MCE, HY-P7109), 250 µg/mL Rspondin-1 (MCE, HY-P7114), and 100 µg/mL Noggin (MCE, HY-P7051A). Organoids formed within 3–4 days and were passaged according to their growth and confluence, which

(5) Investigating bacteria-induced inflammatory responses using novel endometrial epithelial gland organoid modelsFrontiers in Reproductive HealthNovember 12, 2024Xin Zhang, Li Zhang, Ting Li, Zhan Zhang, Xiang Shang, Huihui Bai, Yong Liu, Xiaonan Zong, Chenguang Shang, Dan Song, et al.HY-10432), 250 μg/ml EGF(MCE, HY-P7109), 250 μg/ml R-Spondin-1 (MCE, HY-P7114), 100 μg/ml Noggin (MCE, HY-P7051A). Organoids formed within 3–4 days and were passaged based on growth and confluence, optical microscope,

(6) Impaired AT2 to AT1 cell transition in PM2.5-induced mouse model of chronic obstructive pulmonary diseaseRespiratory researchMarch 25, 2022Yu H, Lin Y, Zhong Y, Guo X, Lin Y, Yang S, Liu J, Xie X, Sun Y, Wang D, et al.(MedChemExpress, HY-P7076), 10 ng/mL FGF10 (MedChemExpress, HY-P7170), 10 ng/mL Noggin (MedChemExpress, HY-P7051A), 10 μmol/L SB-431542 (MedChemExpress, HY-10431) and 3 μmol/L CHIR99021 (MedChemExpress, HY-10182),

(7) An Automated Organoid Platform with Inter-organoid Homogeneity and Inter-patient HeterogeneityCell Reports MedicineDecember 22, 2020Shengwei Jiang et al.11814389001 Nicotinamide,Sigma-Aldrich,Cat# N0636 N-Acetylcysteine,Sigma-Aldrich,Cat# A9165 Noggin (Human),MCE,Cat# HY-P7051A Noggin (Mouse),MCE,Cat# HY-P7086 R-spondin 1,MCE,Cat# HY-P7114 SB431542,MCE,Cat# HY-10431 CHIR99021,MCE,Cat#

(8) In vitro and In vivo imaging of antivasculogenesis induced by Noggin protein expression in human venous endothelial cellsFASEB journal : official publication of the Federation of American Societies for Experimental BiologyDecember 1, 2009Kang HW, Walvick R, Bogdanov A Jr.

(9) Noggin maintains pluripotency of human embryonic stem cells grown on MatrigelCell proliferationAugust 1, 2009Chaturvedi G, Simone PD, Ain R, Soares MJ, Wolfe MW.

(10) The role of noggin in human mesenchymal stem cell differentiationJournal of cellular biochemistryMarch 1, 2007Rifas L.

(11) Human oligodendrocytes derived from embryonic stem cells: Effect of noggin on phenotypic differentiation in vitro and on myelination in vivoMolecular and cellular neurosciencesMarch 1, 2007Izrael M, Zhang P, Kaufman R, Shinder V, Ella R, Amit M, Itskovitz-Eldor J, Chebath J, Revel M.

(12) Bone morphogenic protein-4 induces hypertension in mice: role of noggin, vascular NADPH oxidases, and impaired vasorelaxationCirculationJune 20, 2006Miriyala S, Gongora Nieto MC, Mingone C, Smith D, Dikalov S, Harrison DG, Jo H.

(13) Structural basis of BMP signalling inhibition by the cystine knot protein NogginNatureDecember 12, 2002Groppe J, Greenwald J, Wiater E, Rodriguez-Leon J, Economides AN, Kwiatkowski W, Affolter M, Vale WW, Izpisua Belmonte JC, Choe S.

(14) Noggin, cartilage morphogenesis, and joint formation in the mammalian skeletonScience (New York, N.Y.)May 29, 1998Brunet LJ, McMahon JA, McMahon AP, Harland RM.

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Noggin Protein, Human (CHO) from MedChemExpress

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Noggin Protein, Human (CHO) from MedChemExpress

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