Pam3CSK4 TFA HY-P1180A from MedChemExpress

Product Specs
ItemPam3CSK4 TFA
CompanyMedChemExpress
Price $160.00Supplier Page View Company Product Page
Catalog NumberHY-P1180A
Size1 mg
ApplicationsBioactivity, Structure and function analysis, ELISA, SDS-PAGE, Western blotting
Purity99.81%
TypeChemical
Molecular Weight1852.33
FormulaC₈₁H₁₅₆N₁₀O₁₃S.₃C₂HF₃O₂
Research AreaInflammation/Immunology; Infection

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(1) DPEP2 suppresses hyperinflammation via metabolic reprogramming of macrophages in sepsisNature CommunicationsMarch 9, 2026Wenchen Luo, Wei Xu, Qimeng Yin, Jieqiong Song, Jie Wang, Yian Guan, Jian Huang, Jian Yu, Kefeng Zou, Danfeng Jin, et al.penicillin, and 100 μg/mL streptomycin. RAW264.7 cells were treated with TLR1/2 ligands (1 μg/mL Pam3Csk4; HY-P1180A, MedChemExpress, Monmouth Junction, NJ, USA), TLR7/8 ligands (1 μg/mL R848; HY-13740, MedChemExpress)

(2) Computational-experimental study reveals direct target and bioactives of Ajania fruticulosa against NAFLD via TLR2/NF-κB/PPAR-γ signalingnpj Science of FoodJanuary 23, 2026Chaoyue Chen, Lisha Ma, Awaguli Dawuti, Xin Feng, Shujie Chen, Xueyan An, Yulan Bai, Tianfeng Zhang, Mamatjan Aydin, Kashif Kashmiri, et al.FFA-treated HepG2 cells were co-incubated with TLR2-specific agonist Pam3CSK4 (100 ng/mL; MCE, USA, HY-P1180A) and above compounds for 24 h. WEAF (250 μg/mL) significantly reduced intracellular TG levels, but this

(3) Delaying pyroptosis with an AI-screened gasdermin D pore blocker mitigates inflammatory responseNature immunologyOctober 1, 2025Sun J, Yang J, Tao J, Yang Y, Wang R, Zhang H, Liu W, Zhao S, Shao R, He Y, et al.DCs, DCs were seeded at a density of 1 × 106 cells in 6-cm dishes and treated with 1 µg ml−1 Pam3CSK4 (HY-P1180A, MCE) for 3 h in a cell culture incubator. Following treatment, the cells were washed three times with

(4) Network pharmacology and experimental verification of the mechanism of licochalcone A against Staphylococcus aureus pneumoniaFrontiers in microbiologyJanuary 1, 2024Shen F, Zhang Y, Li C, Yang H, Yuan P.Beyotime Biotechnology (Haimen, China). The NLRP3 activator ATP (HY-B2176) and TLR2 activator Pam3CSK4 (HY-P1180A) were purchased from MedChemExpress (Shanghai, China). Lactate dehydrogenase assay kit (A020-2-2) was

(5) TLR2 agonist Pam3CSK4 enhances the antibacterial functions of GM-CSF induced neutrophils to methicillin-resistant Staphylococcus aureusMicrobial pathogenesisMay 1, 2019Chen Y, Lu S, Zhang Y, Yu J, Deng L, Chen H, Zhang Y, Zhou N, Yuan K, Yu L, et al.

(6) The molecular basis for recognition of bacterial ligands at equine TLR2, TLR1 and TLR6Veterinary researchJuly 4, 2013Irvine KL, Hopkins LJ, Gangloff M, Bryant CE.

(7) Systemic stimulation of TLR2 impairs neonatal mouse brain developmentPloS oneMay 6, 2011Du X, Fleiss B, Li H, D'angelo B, Sun Y, Zhu C, Hagberg H, Levy O, Mallard C, Wang X.

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Pam3CSK4 TFA from MedChemExpress

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Pam3CSK4 TFA from MedChemExpress

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