Tau-441 (2N4R) P301S Mutant Pre-formed Fibrils SPR-471 from StressMarq Biosciences Inc

Product Specs
ItemTau-441 (2N4R) P301S Mutant Pre-formed Fibrils
CompanyStressMarq Biosciences Inc
Price Supplier Page View Company Product Page
Catalog NumberSPR-471
ApplicationsWB, SDS-PAGE, In vivo assay, In vitro assay
Size100 µg
Research AreaAlzheimer's Disease, Axon Markers, Cell Markers, Cell Signaling, Cytoskeleton, Microtubules, MT Associated Proteins, Neurodegeneration, Neuron Markers, Neuroscience, Tangles & Tau
NCBI Full Gene Namemicrotubule associated protein tau
NCBI Gene AliasesTAU, MTBT1, tau-40, PPND, DDPAC, FTDP-17, MSTD, MTBT2, PPP1R103, Tau-PHF6, MAPTL
Conjugate/TagNo Tag
TypeProtein
Source/Expression SystemBaculovirus/Sf9
Purity>95%
SpeciesHuman

Sequence

MAEPRQEFEV MEDHAGTYGL GDRKDQGGYT MHQDQEGDTD AGLKESPLQT PTEDGSEEPG SETSDAKSTP TAEDVTAPLV DEGAPGKQAA AQPHTEIPEG TTAEEAGIGD TPSLEDEAAG HVTQARMVSK SKDGTGSDDK KAKGADGKTK IATPRGAAPP GQKGQANATR IPAKTPPAPK TPPSSGEPPK SGDRSGYSSP GSPGTPGSRS RTPSLPTPPT REPKKVAVVR TPPKSPSSAK SRLQTAPVPM PDLKNVKSKI GSTENLKHQP GGGKVQIINK KLDLSNVQSK CGSKDNIKHV SGGGSVQIVY KPVDLSKVTS KCGSLGNIHH KPGGGQVEVK SEKLDFKDRV QSKIGSLDNI THVPGGGNKK IETHKLTFRE NAKAKTDHGA EIVYKSPVVS GDTSPRHLSN VSSTGSIDMV DSPQLATLAD EVSASLAKQG L

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StressMarq Biosciences Inc

117-1537 Hillside Ave.

Victoria, British Columbia V8T 4Y2

Canada

Phone: +1-250-294-9065
Fax: 1-250-294-9025

Email: info@stressmarq.com

Company Profile

Website: http://www.stressmarq.com

(1) The NORAD -pumilio regulatory axis links lncRNA dysregulation to tau propagation-associated phenotypesbioRxivJuly 3, 2026Joseph E. Zemke, Guangming Huang, Emma Starr, Matthew Broder, Jacob Marsh, Arun Renganathan, Bridget Phillips, Thomas W. Marsh, Miguel Minaya, Carlos Cruchaga, et al.additional 24 hours, 10μM of recombinant Tau-441 (2N4R) P301S Mutant Pre-formed Fibrils (StressMarq, Cat. #SPR-471) were transfected using 5uL of Lipofectamine 2000 (ThermoFisher, Cat. #11668019). After 24 hours, cells

(2) Integrative Genomic and Functional Analyses Reveal NINL as a Modulator of Tau AggregationbioRxiv : the preprint server for biologyDecember 16, 2025Swift SK, Huang G, Cochran JN, Minaya MA, Castruita PA, Miller KJ, Starr E, Galasso G, Marsh JA, Kao AW, et al.

(3) Cholesterol 25-hydroxylase mediates neuroinflammation and neurodegeneration in a mouse model of tauopathyThe Journal of experimental medicineApril 1, 2024Toral-Rios D, Long JM, Ulrich JD, Yu J, Strickland MR, Han X, Holtzman DM, Cashikar AG, Paul SM.recombinant tau-441 (2N4R) P301S mutant protein (0.5 μm) expressed with a Baculovirus/sf9 system (cat. no. SPR-471; StressMarq Biosciences) or PBS in serum-free media. After 24 h, RNA was isolated from cells using the

(4) Polarized microtubule remodeling transforms the morphology of reactive microglia and drives cytokine releaseNature communicationsOctober 9, 2023Adrian M, Weber M, Tsai MC, Glock C, Kahn OI, Phu L, Cheung TK, Meilandt WJ, Rose CM, Hoogenraad CC.(2N4R), Cat No SPR-479) and tau P301S fibril preparations (Human Tau-441 (2N4R) P301S Mutant PFF, Cat No SPR-471, both Stressmarq Biosciences) were added at 4 µg/ml. Nocodazole and taxol (both Sigma) were used at

(5) Increased G3BP2-Tau interaction in tauopathies is a natural defense against Tau aggregationNeuronSeptember 6, 2023Wang C, Terrigno M, Li J, Distler T, Pandya NJ, Ebeling M, Tyanova S, Hoozemans JJM, Dijkstra AA, Fuchs L, et al.

(6) Astrocyte senescence and SASP in neurodegeneration: tau joins the loopCell cycle (Georgetown, Tex.)April 1, 2021Ungerleider K, Beck J, Lissa D, Turnquist C, Horikawa I, Harris BT, Harris CC.

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Tau-441 (2N4R) P301S Mutant Pre-formed Fibrils

Tau-441 (2N4R) P301S Mutant Pre-formed Fibrils

Tau-441 (2N4R) P301S Mutant Pre-formed Fibrils

Tau-441 (2N4R) P301S Mutant Pre-formed Fibrils from StressMarq Biosciences Inc

Description

Sequence

StressMarq Biosciences Inc

Citations (6)

Reviews

Tau-441 (2N4R) P301S Mutant Pre-formed Fibrils from StressMarq Biosciences Inc

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