Human Activin A Recombinant Protein PHC9561 from Thermo Fisher Scientific

Product Specs
ItemHuman Activin A Recombinant Protein
CompanyThermo Fisher Scientific
Price Supplier Page View Company Product Page
Catalog NumberPHC9561
Regulatory StatusFor Research Use Only. Not for use in diagnostic procedures
ApplicationsCELL CULTURE
Size100 µg

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Thermo Fisher Scientific

168 Third Avenue

Waltham, MA 02451

United States

Phone: 800-678-5599

Company Profile

Website: www.thermofisher.com

(1) Immune response to adeno-associated viral vectors in a human iPSC-derived microglia chimeric mouse modelCell Reports MethodsApril 20, 2026Jan R. Detrez, Caroline Eykens, Gaëlle Gillet, Manisha Padmakumar, Sílvia Cabré, Phil Stanley, Julien Gasser, Luke M. Healy, Irena KadiuBMP4 Recombinant Human Protein,ThermoFisher Scientific,PHC9534 Activin A Recombinant Human Protein,ThermoFisher Scientific,PHC9564 Recombinant Human VEGF 165,Peprotech,100–20 Thrombopoietin (TPO) Recombinant Human Protein,ThermoFisher Scientific

(2) Effect of triazine thiols on steady-state mRNA levels in iPSC-derived hepatocytesMicroPubl BiolMarch 6, 2026Carla Martinez-Morant, Jui-Tung Liu, Yu-Lin Jiang, Josef Blaszkiewicz, Stephen A. Duncan2% B27 Supplement without insulin (Invitrogen, MA, #A1895601), 100 ng/mL Activin A (Invitrogen, MA, #PHC9563), 20 ng/mL Fibroblast Growth Factor 2 (FGF2) (Invitrogen, MA, #PHG0023), and 10 ng/mL BMP4 (Invitrogen,

(3) Parkinson's Disease Patient‐Specific Striatum Organoids Show Hallmarks of Increased InflammationMovement DisordersFebruary 11, 2026Kyriaki Barmpa, Claudia Saraiva, Alise Zagare, Mona Tuzza, Joseph Longworth, Elisa Zuccoli, Katrin Hufnagel, Florian Skwirblies, Ronny Schmidt, Dirk Brenner, et al.supplemented with 2.5 μM IWP‐2 (Selleckchem, S7085), and 50 ng/ml Activin A (Thermo Fisher Scientific, PHC9561). From Day 9 to Day 17, the medium was further supplemented with 100 nM SR11237 (Tocris, 3411). Daily

(4) Conserved phenotype and function of human brain border-associated macrophages in iPSC-derived modelsbioRxivDecember 13, 2025Helena J. Barr, Constanze Depp, Maximilian Hingerl, Trang Nguyen, Justin M. Reimertz, Emma Connolly, Jasmin Patel, Jordan L. Doman, Samuel E. Marsh, Beth Stevensand resuspended in iHPC media supplemented with 12.5ng/mL Activin-A (Thermo Fisher Scientific, cat #PHC9564), 50ng/mL BMP4 (Thermo Fisher Scientific, cat #PHC9534), 50ng/mL FGF2 (Thermo Fisher Scientific, cat

(5) The Parkinson's disease-associated LRRK2-G2019S variant restricts serine metabolism, leading to microglial inflammation and dopaminergic neuron degenerationJ NeuroinflammationOctober 27, 2025Henry Kurniawan, Sarah L. Nickels, Alise Zagare, Elisa Zuccoli, Isabel Rosety, Gemma Gomez-Giro, Enrico Glaab, Jens C. SchwambornSRO, ND07996), 10 µM DAPT (R&D Systems, 2634/10) and 2.5 ng/ml Activin A (ThermoFisher Scientific, PHC9564). Organoids were maintained under static conditions with biweekly medium changes until day 15 of differentiation. Coculture

(6) Comparative CRISPRi screens reveal a human stem cell dependence on mRNA translation-coupled quality controlNature structural & molecular biologyOctober 1, 2025Rodschinka G, Forcelloni S, Kühner FM, Wani S, Riemenschneider H, Edbauer D, Behrens A, Nedialkova DD.ml−1 tumor growth factor β3 (Peprotech, AF-100-36E)). Next, 5 ng µl−1 activin A (Life Technologies, PHG9014) was added for the first 2 days of maturation. Cells were cultured for another 10 days, changing the

(7) Novel Dual Mechanism GRT-X Agonist Acting on Kv7 Potassium Channel/Translocator Protein Receptor Prevents Motoneuron Degeneration Following Exposure to Mouse and Human Amyotrophic Lateral Sclerosis/Frontotemporal Dementia Astrocyte-Conditioned MediaACS Chem NeurosciAugust 6, 2025Vera M. Masegosa, Elsa Fritz, Daniela Corvalan, Fabiola Rojas, Polett Garcés, Xavier Navarro, Petra Bloms-Funke, Brigitte van Zundert, Mireia Herrando-Grabulosa[KO DMEM/F12, 1x StemPro NSCs Supplement (Gibco, Cat. #A10508-01), 10 ng/mL Activin A (Gibco, Cat. #PHC9564), 10 ng/mL Heregulin 1b (R&D Systems, Cat. #377-HB-050), 200 ng/mL IGF1 (R&D System, Cat. #P291-G1-200),

(8) Analysis of astrocyte progenitors derived from human induced pluripotent stem cells in vitro and following transplantation into the intact spinal cord.bioRxivJune 29, 2025ALESSIA NICEFORO, Ying Jin, Skandha Ramakrishnan, Maurice Lindner-Jackson, Liang O. Qiang, Itzhak Fischerhuman insulin-like growth factor (IGF)-1 (Peprotech, 100–11), 10 ng/ml human Activin A (Thermo Fisher, PHC9564) and 10 ng/ml recombinant human Heregulinβ1 (Peprotech, 100–03) to convert NPCs to astrocyte progenitor cells

(9) Mitochondrial dysfunction drives a neuronal exhaustion phenotype in methylmalonic aciduriaCommun BiolMarch 11, 2025Matthew C. S. Denley, Monique S. Straub, Giulio Marcionelli, Miriam A. Güra, David Penton, Igor Delvendahl, Martin Poms, Beata Vekeriotaite, Sarah Cherkaoui, Federica Conte, et al.embryo-grade water (Sigma, Cat. W1503)). For one day CDM-PVA was supplemented with 10 ng/mL Activin (Gibco, PHC9564) and 12 ng/mL fibroblast growth factor-2 (FGF2) (Gibco, Cat. PHG0024). Thereafter, lineage specific

(10) Mechanosensitive Differentiation of Human iPS Cell-Derived PodocytesBioengineering (Basel)October 17, 2024Yize Zhang, Samira MusahUSA; 10565018) supplemented with 100 ng mL−1 activin A (Thermo Fisher Scientific, Waltham, MA, USA; PHC9564), 3 μM CHIR99021 (Stemgent, Cambridge, MA, USA; 04-0004), 10 μM Y27632 (TOCRIS, Minneapolis, MN, USA;

(11) Creating a novel method for chicken primordial germ cell health monitoring using the fluorescent ubiquitination-based cell cycle indicator reporter systemPoultry ScienceOctober 1, 2024András Ecker, Bence Lázár, Roland I. Tóth, Martin Urbán, Orsolya I. Hoffmann, Zsófia Fekete, Endre Barta, Ferenc Uher, Zsolt Matula, Eszter Várkonyi, et al.MT, 15070-063), chicken serum (Sigma, St. Louis, MO, C5405), human activin (Invitrogen, Waltham, MA, PHC9564), bFGF2 (Gibco, Billings, MT, 13256-029), and ovotransferrin (Sigma, St. Louis, MO, C7786)(Whyte et

(12) A PNPLA3-Deficient iPSC-Derived Hepatocyte Screen Identifies Pathways to Potentially Reduce Steatosis in Metabolic Dysfunction-Associated Fatty Liver DiseaseInternational Journal of Molecular SciencesJuly 2, 2024Caren Doueiry, Christiana S. Kappler, Carla Martinez-Morant, Stephen A. DuncanSupplement without insulin (Invitrogen, MA, USA, #A1895601), 100 ng/mL of Activin A (Invitrogen, MA, USA, #PHC9563), 20 ng/mL of Fibroblast Growth Factor 2 (FGF2) (Invitrogen, MA, USA, #PHG0023), and 10 ng/mL of BMP4

(13) The Effect of Short- and Long-Term Cryopreservation on Chicken Primordial Germ CellsGenes (Basel)May 14, 2024Mariam Ibrahim, Ewa Grochowska, Bence Lázár, Eszter Várkonyi, Marek Bednarczyk, Katarzyna Stadnicka15070-063), chicken serum (Sigma, St. Louis, MO, USA, C5405), human activin (Invitrogen, Waltham, MA, USA, PHC9564), bFGF2 (Gibco, Billings, MT, USA, 13256-029), and ovotransferrin (Sigma, St. Louis, MO, USA, C7786).

(14) Generation of a human iPSC-derived cardiomyocyte/fibroblast engineered heart tissue modelF1000ResearchFebruary 12, 2024Max J Cumberland, Jonas Euchner, Amar J Azad, Nguyen T N Vo, Paulus Kirchhof, Andrew P Holmes, Chris Denning, Katja GehmlichReconstituted in PBS (0.1 % BSA) to 10 μg/mL and stored at -20 °C in 20 μl aliquots),"ThermoFisher Scientific, PHC9564" RPMI 1640 Medium,"ThermoFisher Scientific, 11875093" "B-27 Supplement, minus insulin","ThermoFisher Scientific

(15) Knockout of the Cardiac Transcription Factor NKX2-5 Results in Stem Cell-Derived Cardiac Cells with Typical Purkinje Cell-like Signal Transduction and Extracellular Matrix FormationInternational journal of molecular sciencesAugust 29, 2023Disse P, Aymanns I, Mücher L, Sandmann S, Varghese J, Ritter N, Strutz-Seebohm N, Seebohm G, Peischard S.50 nM Dorsomorphin (Santa Cruz (Dallas, TX, USA) #sc200689) and 5 ng/mL Activin A (Thermo Fischer #PHC9564). Every 4 days, the cells reached complete confluence and were then split. The cells were washed once

(16) Development of a robust induced pluripotent stem cell atrial cardiomyocyte differentiation protocol to model atrial arrhythmiaStem Cell Research & TherapyJuly 27, 2023Jordan Thorpe, Matthew D. Perry, Osvaldo Contreras, Emily Hurley, George Parker, Richard P. Harvey, Adam P. Hill, Jamie I. VandenberghiPSCs were further induced to mesoderm in RPMI B27 minus insulin supplemented with 8 ng/mL Activin A (PHC9564, ThermoFisher) and 10 ng/mL BMP4 with 1% GlutaMAX. Day 2 cardiac mesoderm specification is induced with

(17) Transcriptional and metabolic programs promote the expansion of follicular helper T cells in lupus-prone miceiScienceMay 19, 2023Gong M, Choi SC, Park YP, Zou X, Elshikha AS, Gerriets VA, Rathmell JC, Mohamazadeh M, Morel L.Supermix,Bio-Rad,1725271 RPMI-1640,Corning,10-040-CV IL-6,Shenandoah Biotech,200-02 IL-21,Pepro Tech,210-21 Activin A,Thermo Fisher,PHC9564 ,, Critical commercial assays,Critical commercial assays,Critical commercial assays ,, RNeasy Kit,Qiagen,74004 TruSeq

(18) Single-cell RNA sequencing reveals maturation trajectory in human pluripotent stem cell-derived cardiomyocytes in engineered tissuesiScienceApril 21, 2023Shangli Cheng, David Brenière-Letuffe, Virpi Ahola, Andy O.T. Wong, Hoi Yee Keung, Bimal Gurung, Zongli Zheng, Kevin D. Costa, Deborah K. Lieu, Wendy Keung, et al.proteins","Chemicals, peptides, and recombinant proteins" ,, BMP4,Thermo Fisher,PHC9531 Activin A,Thermo Fisher,PHC9564 IWR-1,STEMCELL Technologies,"72,564" Papain,Sigma,"76,220" EDTA,Roth,804.2 ,, Deposited data,Deposited

(19) The Effects of Freezing Media on the Characteristics of Male and Female Chicken Primordial Germ Cell LinesLife (Basel)March 23, 2023András Ecker, Bence Lázár, Roland Imre Tóth, Martin Urbán, Nikolett Tokodyné Szabadi, Maria Teresa Salinas Aponte, Mohd Adnan, Eszter Várkonyi, Elen Gócza15070-063), chicken serum (Sigma, St. Louis, MO, USA, C5405), human activin (Invitrogen, Waltham, MA, USA, PHC9564), bFGF2 (Gibco, Billings, MT, USA, 13256-029), and ovotransferrin (Sigma, St. Louis, MO, USA, C7786).

(20) Mature iPSC-derived astrocytes of an ALS/FTD patient carrying the TDP43(A90V) mutation display a mild reactive state and release polyP toxic to motoneuronsFrontiers in cell and developmental biologyJanuary 1, 2023Rojas F, Aguilar R, Almeida S, Fritz E, Corvalán D, Ampuero E, Abarzúa S, Garcés P, Amaro A, Diaz I, et al.[KO DMEM/F12, 1x StemPro NSCs Supplement (Gibco, Cat. #A10508-01), 10 ng/mL Activin A (Gibco, Cat. #PHC9564), 10 ng/mL Heregulin 1β (R&D Systems, Cat. #377-HB-050), 200 ng/mL IGF1 (R&D System, Cat. #P291-G1-200),

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Human Activin A Recombinant Protein from Thermo Fisher Scientific

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Human Activin A Recombinant Protein from Thermo Fisher Scientific

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