Fig 1: A. Plasmablast differentiation after 6 days in culture with CpG/ODN 2006 upper or CD40L+IL21 lower dot plots B. CFSE dilution gated in CD19+ cells (B cell proliferation) after 6 days in culture: unstimulated, CpG/ODN 2006 or CD40L+IL21 C. Plasmablasts frequencies and D. divided cells CD19+ in the patient (red dots) as compare with 3 Healthy controls (blue dots) after 6 days in culture.
Fig 2: A. Plasmablast differentiation after 6 days in culture with CpG/ODN 2006 upper or CD40L+IL21 lower dot plots B. CFSE dilution gated in CD19+ cells (B cell proliferation) after 6 days in culture: unstimulated, CpG/ODN 2006 or CD40L+IL21 C. Plasmablasts frequencies and D. divided cells CD19+ in the patient (red dots) as compare with 3 Healthy controls (blue dots) after 6 days in culture.
Supplier Page from Thermo Fisher Scientific for Recombinant Human IL-21 Protein