Description
MACS GMP Vectofusin-1 is a non-toxic histidin-rich amphipathic peptide which exerts as viral transduction enhancer. Unlike other transduction enhancers, it is not dependent on immobilization of target cells and therefore compatible with automated processes.
Background information
Viral transduction of suspension cells using retroviral vectors is often inefficient and requires the use of transduction enhancers. MACS GMP Vectofusin-1 is a fully synthetic, non-toxic, cationic amphipathic peptide with viral transduction enhancing capacity, enabling higher transduction levels with low amounts of retroviral vector. MACS GMP Vectofusin-1 promotes the entry of several retroviral pseudo-types into target cells when added to the culture medium.
Applications
Enhancement of lentiviral transduction
Enhancement of retroviral transduction