Description
Fibroblast growth factor receptor-1 beta (FGFR1- beta) is an isoform of FGFR1 which is a receptor tyrosine kinase. FGFR1-beta is expressed in basal epithelial cells and smooth muscle cells.1 FGF R1β supports progression and chemoresistance in subsets of acute myeloid leukemias (AML).2