Human ACE2-AVI & His Recombinant Protein, Biotinylated 10108-H27B-B from Sino Biological, Inc.

Product Specs
ItemHuman ACE2-AVI & His Recombinant Protein, Biotinylated
CompanySino Biological, Inc.
Price $298.00Supplier Page View Company Product Page
Catalog Number10108-H27B-B
Size20 µg
Activity1.Immobilized 2019-nCoV Spike Protein (RBD, mFc Tag)(40592-V05H) at 2 µg/mL (100 µL/well) can bind Human ACE2-AVI & His Recombinant Protein, Biotinylated(10108-H27B-B), the EC50 of Human ACE2-AVI & His Recombinant Protein, Biotinylated (10108-H27B-B) is 20-40 ng/mL 2.Loaded Recombinant Human ACE2 Protein, His Tag, Biotinylated (Cat. No. 10108-H27B-B) on SA Biosensor, can bind SARS-CoV-2 (2019-nCoV) Spike RBD-mFc Recombinant Protein (Cat. No. 40592-V05H) with an affinity constant of 1.75 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested)
Conjugate/TagC-AVI, His
FormatLyophilized from sterile 20mM PB, 150mM NaCl, pH 7.0, 5% glycerol
Purity> 90 % as determined by SDS-PAGE
TypeRecombinant protein
Molecular WeightThe recombinant human ACE2 consists 749 amino acids and predicts a molecular mass of 86.86 kDa
SpeciesHuman
Molecule NameACE2
Source/Expression SystemBaculovirus-Insect Cells
NCBI Full Gene Nameangiotensin converting enzyme 2
NCBI Gene AliasesACEH

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) Novel Regioselective Approach to Cyclize Phage-Displayed Peptides in Combination with Epitope-Directed Selection to Identify a Potent Neutralizing Macrocyclic Peptide for SARS-CoV-2ACS Chemical BiologySeptember 29, 2022J. Trae Hampton, Tyler J. Lalonde, Jeffery M. Tharp, Yadagiri Kurra, Yugendar R. Alugubelli, Christopher M. Roundy, Gabriel L. Hamer, Shiqing Xu, Wenshe Ray Liuthat had been preincubated for 30 min with 12.5 μL of Biotinylated-ACE2 (Sino Biological, Cat. No. 10108-H27B-B). After a 30-min incubation at 37 °C, 25 μL of premixed acceptor/donor beads were then added to the

(2) BA.2.12.1, BA.4 and BA.5 escape antibodies elicited by Omicron infectionNatureAugust 1, 2022Cao Y, Yisimayi A, Jian F, Song W, Xiao T, Wang L, Du S, Wang J, Li Q, Chen X, et al.h. After blocking, the plates were washed 5 times, and the mixture of ACE2–biotin (Sino Biological, 10108-H27B-B) and serially diluted competitor antibodies was added followed by 30 min incubation at room temperature.

(3) Peptide Binder with High-Affinity for the SARS-CoV-2 Spike Receptor-Binding DomainACS applied materials & interfacesJune 29, 2022Yu L, Wang R, Wen T, Liu L, Wang T, Liu S, Xu H, Wang C.40592-V08H90 (Delta), 40592-V08H121 (Omicron)). Biotinylated ACE2 protein was purchased from Sino Biological (10108-H27B-B). Vero E6, Beas, and A549 cells were purchased from the Peking Union Medical College Cell Culture Center.

(4) Histones released by NETosis enhance the infectivity of SARS-CoV-2 by bridging the spike protein subunit 2 and sialic acid on host cellsCellular & molecular immunologyMay 1, 2022Hong W, Yang J, Zou J, Bi Z, He C, Lei H, He X, Li X, Alu A, Ren W, et al.(Sino Biological, 40590-V08B-B), RBD (Sino Biological, 40592-V08B-B) or ACE2 proteins (Sino Biological, 10108-H27B-B) at concentrations of 0, 1, 5, 10, 25, 50, or 100 nM were added to each well and incubated at room temperature

(5) Integrin mediates cell entry of the SARS-CoV-2 virus independent of cellular receptor ACE2The Journal of biological chemistryMarch 1, 2022Liu J, Lu F, Chen Y, Plow E, Qin J.experiment showing no significant interaction between immobilized biotinylated ACE2 (SINO BIOLOGICAL #10108-H27B-B) and integrin α5β1.

(6) Neutralization of SARS-CoV-2 by highly potent, hyperthermostable, and mutation-tolerant nanobodiesThe EMBO journalOctober 1, 2021Güttler T, Aksu M, Dickmanns A, Stegmann KM, Gregor K, Rees R, Taxer W, Rymarenko O, Schünemann J, Dienemann C, et al.containing VHHs for 450 s and then buffer for 900 s. ACE2 competition experiments Biotinylated Human ACE2 (10108‐H27B‐B, Sino Biological) was immobilized on biosensors until a 0.5 nm wavelength shift/binding signal was reached.

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Human ACE2-AVI & His Recombiant Protein, Biotinylated

Human ACE2-AVI & His Recombinant Protein, Biotinylated from Sino Biological, Inc.

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Sino Biological, Inc.

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Human ACE2-AVI & His Recombinant Protein, Biotinylated from Sino Biological, Inc.

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