Human ACE2 / Angiotensin-Converting Enzyme 2 Protein (His Tag), Biotinylated 10108-H08H-B from Sino Biological, Inc.

Product Specs
ItemHuman ACE2 / Angiotensin-Converting Enzyme 2 Protein (His Tag), Biotinylated
CompanySino Biological, Inc.
Price $248.00Supplier Page View Company Product Page
Catalog Number10108-H08H-B
Size20 µg
FormatLyophilized from sterile PBS, pH 7.4
Conjugate/TagC-His
Purity≥ 95 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC
ActivityImmobilized SARS-CoV-2 Spike Protein (RBD, mFc Tag) (Cat: 40592-V05H) at 2 µg/mL (100 µL/well) can bind human ACE2 protein (His tag), Biotinylated(Cat: 10108-H08H-B), the EC50 of human ACE2 protein (His tag), Biotinylated(Cat: 10108-H08H-B) is 20-130 ng/mL
TypeRecombinant protein
Molecule NameACE2
SpeciesHuman
Source/Expression SystemHEK293 Cells
Molecular WeightThe recombinant human ACE2 consists of 734 amino acids and predicts a molecular mass of 85.1 kDa
NCBI Full Gene Nameangiotensin converting enzyme 2
NCBI Gene AliasesACEH

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) Serology survey against multiple SARS-CoV-2 variants of residents in Tainan, TaiwanVirulenceApril 14, 2026I-Lin Hsu, Pin-Xian Du, Ting-Mao Chou, Chung-Che Cheng, Pei-Shan Tsai, Hsi-Chang Shih, Shu-Chuan Chen, Chung-Yi Li, Tzong-Shiann Ho, Guan-Da Syuarray was then incubated with biotinylated Angiotensin-converting enzyme 2 (ACE2, Sino Biological, #10108-H08H-B) in a serial dilution starting at 0.125 ng/mL, diluted 2-fold, and incubated for 1 h. The array was

(2) Broadening SARS-CoV-2 Immunity by Combining ORFV and Protein-Based VaccinesVaccines (Basel)January 4, 2026Alena Reguzova, Melanie Müller, Madeleine Fandrich, Alex Dulovic, Ralf Amannsamples were diluted with assay buffer and then ACE2 buffer (300 ng/mL biotinylated ACE2, cat. no. 10108-H08H-B, Sino Biological), before being combined 1:1 with the bead mix in 96 well plates (cat. no. 3642, Corning,

(3) Heterologous ORFV–Ad26 vaccination broadens antibody breadth and amplifies cellular immunity against SARS-CoV-2 spikeFrontiers in ImmunologyNovember 18, 2025Alena Reguzova, Verena Haug, Melanie Müller, Madeleine Fandrich, Alex Dulovic, Ralf Amannsamples were diluted with assay buffer and then ACE2 buffer (300 ng/mL biotinylated ACE2, cat. no. 10108-H08H-B, Sino Biological), before being combined 1:1 with the bead mix in 96 well plates (cat. no. 3642, Corning,

(4) Magnetic bead-based electrochemical surrogate virus neutralization test for quantification of antibody neutralizing efficiencyBiosensors and BioelectronicsNovember 1, 2025Rae A. Bellows, Kira L. Rahn, Wyatt C. Hummel, E. Handly Handly Mayton, Henri W. Berry, Elizabeth P. Ryan, Brian J. Geiss, David S. Dandy, Charles S. HenryThermo Fisher Scientific, Waltham, MA, USA) and 2 μL of 0.25 μg/μL ACE2 conjugated to biotin (Cat. No. 10108-H08H-B, SinoBiological) were added to the tube. Detailed information about the preparation of the 1 mg/mL magnetic

(5) Heterologous prime-boost vaccination with VLA2001 and an ORFV-based vector enhances spike- and nucleocapsid-specific immunity in miceFrontiers in ImmunologySeptember 18, 2025Alena Reguzova, Verena Haug, Carina Metz, Melanie Müller, Madeleine Fandrich, Alex Dulovic, Ralf Amannsamples were diluted with assay buffer and then ACE2 buffer (300 ng/mL biotinylated ACE2, cat. no. 10108-H08H-B, Sino Biological), before being combined 1:1 with the bead mix in 96 well plates (cat. no. 3642, Corning,

(6) Angiotensin Converting Enzyme 2 is a molecular decoy for targeted photodynamic SARS-CoV-2 inactivationInternational journal of biological macromoleculesAugust 1, 2025Mussini A, Mariangeli M, Delcanale P, Abbruzzetti S, Bianchini P, Diaspro A, Lelli D, Moreno A, Viappiani C.

(7) Comprehensive analysis of nasal IgA antibodies induced by intranasal administration of the SARS-CoV-2 spike proteinElifeMay 8, 2025Kentarou Waki, Hideki Tani, Eigo Kawahara, Yumiko Saga, Takahisa Shimada, Emiko Yamazaki, Seiichi Koike, Yoshitomo Morinaga, Masaharu Isobe, Nobuyuki KurosawaTag",Acro Biosystems,SPD-C52Hh,B.1.617.2/Delta Recombinant protein,Biotinylated Human ACE2,Sino Biological,10108-H08H-B, Recombinant protein,"SARS-CoV-2 S protein, His Tag, Super stable trimer",Acro Biosystems,SPN-C52H9,Wuhan Recombinant

(8) Comprehensive analysis of nasal IgA antibodies induced by intranasal administration of the SARS-CoV-2 spike proteinElifeMay 8, 2025Kentarou Waki, Hideki Tani, Eigo Kawahara, Yumiko Saga, Takahisa Shimada, Emiko Yamazaki, Seiichi Koike, Yoshitomo Morinaga, Masaharu Isobe, Nobuyuki KurosawaTag",Acro Biosystems,SPD-C52Hh,B.1.617.2/Delta Recombinant protein,Biotinylated Human ACE2,Sino Biological,10108-H08H-B, Recombinant protein,"SARS-CoV-2 S protein, His Tag, Super stable trimer",Acro Biosystems,SPN-C52H9,Wuhan Recombinant

(9) Role of glycosylation mutations at the N-terminal domain of SARS-CoV-2 XEC variant in immune evasion, cell-cell fusion, and spike stabilityJournal of VirologyApril 15, 2025Pei Li, Julia N. Faraone, Cheng Chih Hsu, Michelle Chamblee, Yajie Liu, Yi-Min Zheng, Yan Xu, Claire Carlin, Jeffrey C. Horowitz, Rama K. Mallampalli, et al.transfection, cells were then treated with or without 10 µg/mL soluble ACE2 (Sino Biological, Cat# 10108-H08H-B) and incubated for 4 hours at 37°C to induce S1 shedding. Cell culture media and lysates were then collected.

(10) Heterologous prime-boost vaccination with VLA2001 and an ORFV-based vector enhances spike- and nucleocapsid-specific immunity in miceFrontiers in immunologyJanuary 1, 2025Reguzova A, Haug V, Metz C, Müller M, Fandrich M, Dulovic A, Amann R.samples were diluted with assay buffer and then ACE2 buffer (300 ng/mL biotinylated ACE2, cat. no. 10108-H08H-B, Sino Biological), before being combined 1:1 with the bead mix in 96 well plates (cat. no. 3642, Corning,

(11) Evolving antibody response to SARS-CoV-2 antigenic shift from XBB to JN.1NatureNovember 7, 2024Fanchong Jian, Jing Wang, Ayijiang Yisimayi, Weiliang Song, Yanli Xu, Xiaosu Chen, Xiao Niu, Sijie Yang, Yuanling Yu, Peng Wang, et al.improperly folded RBD variants in XBB.1.5 and JN.1 DMS libraries were removed using ACE2 (Sino Biological, 10108-H08H-B) conjugated biotin binder beads (Thermo Fisher, 11533D). After being washed with PBSA, the beads that

(12) CD81 fusion alters SARS-CoV-2 Spike traffickingmBioSeptember 11, 2024Cone AS, Zhou Y, McNamara RP, Eason AB, Arias GF, Landis JT, Shifflett KW, Chambers MG, Yuan R, Willcox S, et al.

(13) Discovery of a novel inhibitor of macropinocytosis with antiviral activityMolecular TherapySeptember 4, 2024Bartlomiej Porebski, Wanda Christ, Alba Corman, Martin Haraldsson, Myriam Barz, Louise Lidemalm, Maria Häggblad, Juliana Ilmain, Shane C. Wright, Matilde Murga, et al.interferometry, using recombinant His-tagged and biotinylated human ACE2 protein (Sino Biological, cat. no. 10108-H08H-B) and recombinant SARS-CoV-2 His-tagged S protein (Sino Biological, cat. no. 40591-V08H). Binding was

(14) Immunogenicity and protective efficacy of the HC009 mRNA vaccine against SARS-CoV-2Frontiers in ImmunologyJuly 26, 2024Juan Liu, Huafeng Han, Binbin Yang, Naifang Zhang, Jing Li, Xicheng Chen, Jie Wu, Yingying Zhao, Yongsheng YangHEK293 cells were then collected and incubated with 5 μg/mL human biotinylated hACE2 protein (Sino Biological, 10108-H08H-B, China) and then with 10 μg/mL PE-Streptavidin antibody (Thermo Fisher Scientific, 12–4317-87, USA)

(15) Mammalian cell display with automated oligo design and library assembly allows for rapid residue level conformational epitope mappingCommunications biologyJuly 3, 2024Thalén NB, Karlander M, Lundqvist M, Persson H, Hofström C, Turunen SP, Godzwon M, Volk AL, Malm M, Ohlin M, et al.immobilization: 6 min) to a level of approximately 1000 RU followed by binding of 50 nM biotinylated ACE2 (10108-H08H-B, SinoBiological (Beijing, China)) (flow rate: 10 µl/s; time of binding: 2 min) to the immobilized streptavidin.

(16) Rational in silico design identifies two mutations that restore UT28K SARS-CoV-2 monoclonal antibody activity against Omicron BA.1Structure (London, England : 1993)March 7, 2024Ozawa T, Ikeda Y, Chen L, Suzuki R, Hoshino A, Noguchi A, Kita S, Anraku Y, Igarashi E, Saga Y, et al.

(17) High-throughput screening of genetic and cellular drivers of syncytium formation induced by the spike protein of SARS-CoV-2Nature Biomedical EngineeringNovember 23, 2023Charles W. F. Chan, Bei Wang, Lang Nan, Xiner Huang, Tianjiao Mao, Hoi Yee Chu, Cuiting Luo, Hin Chu, Gigi C. G. Choi, Anderson H C Shum, et al.mM EDTA, washed once with 5% FBS in PBS, then incubated with 100 nM biotinylated human ACE2 protein (10108-H08H-B, SinoBiological) for 2 h at 4 °C. After washing twice with PBS, cells were incubated with streptavidin

(18) Correlation between Clinical Characteristics and Antibody Levels in COVID-19 Convalescent Plasma Donor CandidatesVirusesJune 12, 2023Uzun G, Müller R, Althaus K, Becker M, Marsall P, Junker D, Nowak-Harnau S, Schneiderhan-Marra N, Klüter H, Schrezenmeier H, et al.multiplex RBDCoV-ACE2 assay, as previously described [22]. Biotinylated human ACE2 (Sino Biological, # 10108-H08H-B, Beijing, China) was added to the assay buffer for a final concentration of 342.9 ng/mL to prepare ACE2

(19) Profiling Humoral Immunity After Mixing and Matching COVID-19 Vaccines Using SARS-CoV-2 Variant Protein MicroarraysMolecular & Cellular ProteomicsApril 1, 2023Ho-Chang Kuo, Kuang-Che Kuo, Pin-Xian Du, Batuhan Birol Keskin, Wen-Yu Su, Tzong-Shiann Ho, Pei-Shan Tsai, Chi Ho Pau, Hsi-Chang Shih, Ying-Hsien Huang, et al.#109-165-064), and 39 ng/ml human biotinylated angiotensin-converting enzyme 2 (ACE2) (Sino Biological, #10108-H08H-B) with 1.8 ug/ml Cy5-conjugated Streptavidin (Jackson ImmunoResearch, #016-170-084). Subjects and Plasma

(20) A Competitive Panning Method Reveals an Anti-SARS-CoV-2 Nanobody Specific for an RBD-ACE2 Binding SiteVaccinesFebruary 6, 2023He S, Wang J, Chen H, Qian Z, Hu K, Shi B, Wang J.microlitres of VHH solution (1, 0.5, 0.2, 0.1 µg/mL) was mixed well with 50 μL of biotinylated ACE2 (#10108-H08H-B, Sino Biological, Beijing, China) solution (1.6 µg/mL), and an equal volume of VHH solution mixed with

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Human ACE2 / Angiotensin-Converting Enzyme 2 Protein (His Tag), Biotinylated

Human ACE2 / Angiotensin-Converting Enzyme 2 Protein (His Tag), Biotinylated from Sino Biological, Inc.

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Sino Biological, Inc.

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Human ACE2 / Angiotensin-Converting Enzyme 2 Protein (His Tag), Biotinylated from Sino Biological, Inc.

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