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Vismodegib (GDC-04491)
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Vismodegib (GDC-04491)
Vismodegib (GDC-04491)
Vismodegib (GDC-04491)
Vismodegib (GDC-04491) from BPS Bioscience, Inc.
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Citations:
(1)
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BPS Bioscience, Inc. for
Vismodegib (GDC-04491)
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Description
Vismodegib (GDC-0449) is a potent hedgehog (Hh) signaling pathway inhibitor
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Vismodegib (GDC-04491)
Company
BPS Bioscience, Inc.
Price
$180.00
Supplier Page
View Company Product Page
Catalog Number
27010
Size
25 mg
Purity
≥99% by HPLC
Molecular Weight
421.3 Da
Formula
C
19
H
14
Cl
2
N
2
O
3
S
Activity
Inhibits two ABC transporters, ABCG2/BCRP and ABCB1/Pgp, with IC50 values of 1.4 and 3.0 µM, respectively
Format
A crystalline solid
Type
Inhibitor
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BPS Bioscience, Inc.
6405 Mira Mesa Blvd
Suite 100
San Diego
,
CA
92121
United States
Phone
: 858-202-1401
Email: sales-team@bpsbioscience.com
Company Profile
Website:
https://bpsbioscience.com/
Citations (1)
(1)
Triterpenoid derivatives inhibit Gli-mediated transcription in human glioblastoma cell line via direct interaction with Gli1
Journal of Biological Chemistry
September 1, 2025
Ivo Frydrych, Jiří Řehulka, Lucie Slavíková, Jiří Hodoň, Jan Pokorný, Veronika Šidová, Martina Medvedíková, Hanuš Slavík, Pavel Polishchuk, Tomáš Oždian,
et al.
Smoothened agonist (SAG;
sc-202814
) were obtained from
Santa Cruz
.
Cyclopamine
(
BPS
-
27013
) and GDC0449 (
BPS
-
27010
) were obtained from BPS Bioscience. All
inhibitors
and agonists were dissolved in DMSO (
Sigma-Aldrich
)
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Vismodegib (GDC-04491) from BPS Bioscience, Inc.
Supplier Page
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$180.00
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