HDAC2, FLAG-tag Recombinant 50052 from BPS Bioscience, Inc.

Product Specs
ItemHDAC2, FLAG-tag Recombinant
CompanyBPS Bioscience, Inc.
Price $440.00Supplier Page View Company Product Page
Catalog Number50052
Size50 µg
Conjugate/TagC-terminal FLAG-tag
FormatAqueous buffer solution
Molecular Weight60 kDa
SpeciesHuman
Domain/Region/Terminusfull length
NCBI Full Gene Namehistone deacetylase 2
NCBI Gene AliasesKDAC2, HD2, YAF1, RPD3
TypeProtein
Source/Expression SystemSf9 cells
insect
ApplicationsUseful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling

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BPS Bioscience, Inc.

6405 Mira Mesa Blvd

Suite 100

San Diego, CA 92121

United States

Phone: 858-202-1401

Email: sales-team@bpsbioscience.com

Company Profile

Website: https://bpsbioscience.com/

(1) Cellular Target Engagement and Dissociation Kinetics of Class I-Selective Histone Deacetylase (HDAC) InhibitorsInternational Journal of Molecular SciencesMarch 26, 2026Irina Honin, Zora Novakova, Felix Feller, Simon Schneider, Linda Schäker-Hübner, Cyril Barinka, Finn K. Hansen(BPS Bioscience Inc., San Diego, CA, USA, #50051), HDAC2 (BPS Bioscience Inc., San Diego, CA, USA; #50052) or HDAC3/NCoR (BPS Bioscience Inc., San Diego, CA, USA; #50053) in assay buffer were added. Following

(2) Ortho -Hydroxyanilides: Slow-Acting, Selective Histone Deacetylase 1/2 Inhibitors Suitable for Photocaging ApplicationsACS Pharmacology & Translational ScienceDecember 12, 2025Irina Honin, Tao Sun, Nisha Setia, Linda Schäker-Hübner, Finn K. Hansen(BPS Bioscience Inc., San Diego, CA, USA, #50051), HDAC2 (BPS Bioscience Inc., San Diego, CA, USA, #50052), HDAC3 (BPS Bioscience Inc., San Diego, CA, USA, #50053), or HDAC6 (PBS Bioscience Inc., San Diego,

(3) Preclinical Characterization of SDFZ‐8, a Highly Potent HDAC1 Inhibitor, for Cancer ImmunotherapyMedComm (2020)December 1, 2025Yi Zhou, Jintong Du, Xue Li, Huajun Zhao, Junxin Xue, Yuchen Liu, Xinying Yang, Jinming Yu, Xuben Hou, Hao FangIn detail, the HeLa nuclear extract, HDAC1 (BPS BIOSCIENCE INC, 50051), HDAC2 (BPS BIOSCIENCE Inc; 50052), HDAC3/NCOR1 complex (BPS BIOSCIENCE Inc; 50003), HDAC4 (BPS BIOSCIENCE Inc; 50004), HDAC5 (BPS BIOSCIENCE Inc

(4) DCAF16-Based Covalent Molecular Glues for Targeted Protein Degradation of Histone DeacetylasesArch Pharm (Weinheim)July 9, 2025Tao Sun, Shiyang Zhai, Stephan Lepper, Beate König, Mateo Malenica, Irina Honin, Finn K. Hansenwere added. Human recombinant HDAC1 (BPS Bioscience, Catalog# 50051), HDAC2 (BPS Bioscience, Catalog# 50052), HDAC3/NcoR2 (BPS Bioscience, Catalog# 50003), or HDAC6 (BPS Bioscience, Catalog# 50006) was used.

(5) Exploring Alternative Zinc-Binding Groups in Histone Deacetylase (HDAC) Inhibitors Uncovers DS-103 as a Potent Ethylhydrazide-Based HDAC Inhibitor with Chemosensitizing PropertiesJournal of Medicinal ChemistryFebruary 27, 2025Daniel Stopper, Lukas Biermann, Paris R. Watson, Jingyu Li, Beate König, Matthew N. Gaynes, Lais Pessanha Pessanha de Carvalho, Jana Klose, Maria Hanl, Alexandra Hamacher, et al.respective human recombinant enzyme (HDAC1 (BPS Bioscience, Catalog# 50051); HDAC2 (BPS Bioscience, Catalog# 50052); HDAC3/NcoR2 (BPS Bioscience, Catalog# 50003); HDAC6 (BPS Bioscience, Catalog# 50006)) and diluted

(6) Development of the First-in-Class FEM1B-Recruiting Histone Deacetylase DegradersJournal of Medicinal ChemistryJanuary 23, 2025Felix Feller, Irina Honin, Martina Miranda, Heiko Weber, Svenja Henze, Maria Hanl, Finn K. Hansensolution. Human recombinant HDAC1 (Catalog# 50051, BPS Bioscience, San Diego, CA, USA), HDAC2 (Catalog# 50052, BPS Bioscience), HDAC4 (Catalog# 50004, BPS Bioscience), or HDAC6 (Catalog# 50006, BPS Bioscience)

(7) Micro-scale screening of genetically modified Fusarium fujikuroi strain extends the apicidin familyNatural Products and BioprospectingDecember 1, 2024Alica Fischle, Mika Lutsch, Florian Hübner, Linda Schäker-Hübner, Lina Schürmann, Finn K. Hansen, Svetlana A. Kalininabuffer) and 10 µL enzyme solution (HDAC1-BPS Bioscience, Catalog# 50051; HDAC2-BPS Bioscience, Catalog# 50052; HDAC3/NcoR2-BPS Bioscience, Catalog# 50003; HDAC6-BPS Bioscience, Catalog# 50,006) were added. Next,

(8) Exploration of Hydrazide-Based HDAC8 PROTACs for the Treatment of Hematological Malignancies and Solid TumorsJournal of medicinal chemistryAugust 22, 2024Zhao C, Zhang J, Zhou H, Setroikromo R, Poelarends GJ, Dekker FJ.(BPS Bioscience, Catalog#: 50051), Human recombinant C-terminal FLAG-tag HDAC2 (BPS Bioscience, Catalog#: 50052), human recombinant C-terminal His-tag HDAC3/NcoR2 (BPS Bioscience, Catalog#: 50003) and human recombinant

(9) Development of First-in-Class Dual Sirt2/HDAC6 Inhibitors as Molecular Tools for Dual Inhibition of Tubulin DeacetylationJournal of Medicinal ChemistryNovember 9, 2023Laura Sinatra, Anja Vogelmann, Florian Friedrich, Margarita A. Tararina, Emilia Neuwirt, Arianna Colcerasa, Philipp König, Lara Toy, Talha Z. Yesiloglu, Sebastian Hilscher, et al.Human recombinant HDAC1 (BPS Bioscience, catalogue no. 50051), HDAC2 (BPS Bioscience, catalogue no. 50052), HDAC3/NcoR2 (BPS Bioscience, catalogue no. 50003), or HDAC6 (BPS Bioscience, catalogue no. 50006)

(10) Difluoromethyl-1,3,4-oxadiazoles Are Selective, Mechanism-Based, and Essentially Irreversible Inhibitors of Histone Deacetylase 6Journal of medicinal chemistryOctober 12, 2023König B, Watson PR, Reßing N, Cragin AD, Schäker-Hübner L, Christianson DW, Hansen FK.solution (human recombinant HDAC1 (BPS Bioscience, Catalog# 50051); HDAC2 (BPS Bioscience, Catalog# 50052); HDAC3/NcoR2 (BPS Bioscience, Catalog# 50003); HDAC4 (BPS Bioscience, Catalog# 50004); HDAC6 (BPS Bioscience,

(11) Development of Fluorinated Peptoid-Based Histone Deacetylase (HDAC) Inhibitors for Therapy-Resistant Acute LeukemiaJournal of Medicinal ChemistryNovember 24, 2022Nina Reßing, Julian Schliehe-Diecks, Paris R. Watson, Melf Sönnichsen, Abigail D. Cragin, Andrea Schöler, Jing Yang, Linda Schäker-Hübner, Arndt Borkhardt, David W. Christianson, et al.10 μL of human recombinant HDAC1 (BPS Bioscience, Catalog# 50051), HDAC2 (BPS Bioscience, Catalog# 50052), HDAC3/NcoR2 (BPS Bioscience, Catalog# 50003) or full length HDAC6 (BPS Bioscience, Catalog# 50006)

(12) Development and Biological Evaluation of the First Highly Potent and Specific Benzamide-Based Radiotracer [¹⁸F]BA3 for Imaging of Histone Deacetylases 1 and 2 in BrainPharmaceuticals (Basel, Switzerland)March 8, 2022Clauß O, Schäker-Hübner L, Wenzel B, Toussaint M, Deuther-Conrad W, Gündel D, Teodoro R, Dukić-Stefanović S, Ludwig FA, Kopka K, et al.Inc., San Diego, CA, USA, Catalog# 50051); HDAC2 (BPS Bioscience Inc., San Diego, CA, USA, Catalog# 50052); HDAC3/NcoR2 (BPS Bioscience Inc., San Diego, CA, USA, Catalog# 50003); HDAC6 (BPS Bioscience Inc.,

(13) Synthesis and pharmacological evaluation of pomalidomide derivatives useful for sickle cell disease treatmentBioorganic ChemistrySeptember 1, 2021Thais Regina Ferreira de Melo et al.ng/reaction, BPS Bioscience, catalog #50051; and HDAC-2, 7.2 ng/reaction, BPS Bioscience, catalog #50052) and compound 3d (0.3 μM) or vorinostat at 3 nM and 30 nM. After enzymatic reactions, 50 μL of 2x HDAC

(14) Multicomponent Synthesis, Binding Mode, and Structure-Activity Relationship of Selective Histone Deacetylase 6 (HDAC6) Inhibitors with Bifurcated Capping GroupsJournal of medicinal chemistrySeptember 24, 2020Reßing N, Sönnichsen M, Osko JD, Schöler A, Schliehe-Diecks J, Skerhut A, Borkhardt A, Hauer J, Kassack MU, Christianson DW, et al.10 μL of human recombinant HDAC1 (BPS Bioscience, Catalog# 50051), HDAC2 (BPS Bioscience, Catalog# 50052), HDAC3/NcoR2 (BPS Bioscience, Catalog# 50003) or HDAC6 (BPS Bioscience, Catalog# 50006) at 37 °C. After

(15) Inhibitory selectivity among class I HDACs has a major impact on inflammatory gene expression in macrophagesEuropean Journal of Medicinal ChemistrySeptember 1, 2019Fangyuan Cao, Martijn R.H. Zwinderman, Ronald van Merkerk, Petra E. Ettema, Wim J. Quax, Frank J. Dekker(BPS Bioscience, Catalog #: 50051), human recombinant C-terminal FLAG-tag HDAC 2 (BPS SC Bioscience, Catalog #: 50052) or human recombinant C-terminal His-tag HDAC 3/NcoR2 (BPS Bioscience, Catalog #: 50003) were diluted

(16) Selectivity and Kinetic Requirements of HDAC Inhibitors as Progranulin Enhancers for Treating Frontotemporal DementiaCell chemical biologyJuly 20, 2017She A, Kurtser I, Reis SA, Hennig K, Lai J, Lang A, Zhao WN, Mazitschek R, Dickerson BC, Herz J, et al.appropriate concentration in HDAC assay buffer (HDAC1, BPS Biosciences #50051, 30 ng; HDAC2, BPS Biosciences #50052, 45 ng; HDAC3, BPS Biosciences #50003, 12ng) and left to incubate for desired amount of time (0–3 hours).

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HDAC2, FLAG-tag Recombinant

HDAC2, FLAG-tag

HDAC2, FLAG-tag Recombinant from BPS Bioscience, Inc.

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BPS Bioscience, Inc.

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HDAC2, FLAG-tag Recombinant from BPS Bioscience, Inc.

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