Fig 1: Mosaic plot of proportions of participants with positive autoantibody status. Mosaic plot of proportions of healthy control participants (HC) and severe eosinophilic asthma (SEA) patients negative or positive for serum autoantibodies to at least one of ColV, MPO, TREM1, or IL1R2. Positive defined as an ELISA OD above ULN. Boxes sized relative to patient number. p-value for chi-squared test.
Fig 2: Analysis of FANTOM5 CAGE-sequencing tissue repository dataset. (A) Heatmap showing CAGE-Seq expression of cell-specific gene sets in peripheral blood subsets from FANTOM5. (B) Bar charts comparing transcript expression levels of eosinophil-specific genes MPO, EPX, TREM1, and IL1R2 in human peripheral blood subsets.
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