Human Interleukin-2 / IL-2 Protein GMP-11848-HNAE from Sino Biological, Inc.

Product Specs
ItemHuman Interleukin-2 / IL-2 Protein
CompanySino Biological, Inc.
Price $648.00Supplier Page View Company Product Page
Catalog NumberGMP-11848-HNAE
Activity1. Measured in a cell proliferation assay using CTLL2. The ED50 for this effect is typically 1-8 ng/mL. The specific activity of recombinant human IL-2 is approximately 20,000 IU/µg. 2. Using the Octet RED System, the affinity constant (Kd) of IL2 Protein, Human, Recombinant (Cat. GMP-11848-HNAE) bound Anti-IL2 Antibody (Cat. 11848-MM03) was 0.1 nM
Conjugate/TagUnconjugated
FormatSupplied as sterile 20mM HAc-NaAc+0.004% Tween-80 pH 4.0
Purity≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC
TypeRecombinant protein
Molecular WeightThe recombinant human IL-2 consists of 134 amino acids and predicts a molecular mass of 15.5 kDa
SpeciesHuman
Molecule NameIL2
Source/Expression SystemE. coli
NCBI Full Gene Nameinterleukin 2
NCBI Gene AliasesIL-2, TCGF, lymphokine
Size500 µg

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) High NLRC5 Expression Is Associated with an Immunosuppressive Tumor Microenvironment and Poor Prognosis in Esophageal Squamous Cell CarcinomaCancers (Basel)March 30, 2026Heng Xiao, Jingyue Fan, Jinyun Zhang, Caixia Cheng, Bin Song, Ling Zhang, Yanghui Bi, Xiaolong Chengserum and 400 IU/mL recombinant human interleukin-2 (IL-2; Sino Biological Inc., Beijing, China, Cat#GMP-11848-HNAE). 2.13. Electroporation of CAR-T Cells CRISPR/Cas9-mediated gene editing in primary human T cells

(2) Phosphoantigen-induced inside-out stabilization of butyrophilin receptor complexes drives dimerization-dependent γδ TCR activationImmunityJuly 8, 2025Zhu Y, Gao W, Zheng J, Bai Y, Tian X, Huang T, Lu Z, Dong D, Zhang A, Guo C, et al.

(3) A novel anti-OX40 human monoclonal antibody that blocks OX40/OX40L signaling and depletes OX40+ T cellsMarine Life Science & TechnologyApril 7, 2025Zhen Li, Lin Liu, Xiaobo Chen, Yanqing Wang, Yuxuan Wang, Yuxiu Zhang, Bingqiang Zhang, Xiao Wu, Muhammad Omer Iqbal, Jin Chen, et al.of PHA (Roche, 11,249,738,001) and 20 ng/mL of hIL-2 (Farcet et al. 1984) (Sino Biological, China, GMP-11848-HNAE). Furthermore, JY007, KHK4083, and OX40L-mFc were incubated with the activated T cells at 4 °C for 1

(4) Miltefosine reinvigorates exhausted T cells by targeting their bioenergetic stateCell reports. MedicineDecember 17, 2024Zhang X, Zhang C, Lu S, Dong J, Tang N, Wang Y, Han W, Pan X, Zhang X, Liu D, et al.heat-inactivated fetal bovine serum and 400 IU/mL recombinant human IL-2 (Sino Biological Inc., Cat#GMP-11848-HNAE). Cryopreservation was performed at a concentration of 2 × 107 T cells per vial. Study approval All

(5) All-RNA-mediated targeted gene integration in mammalian cells with rationally engineered R2 retrotransposonsCellAugust 22, 2024Chen Y, Luo S, Hu Y, Mao B, Wang X, Lu Z, Shan Q, Zhang J, Wang S, Feng G, et al.

(6) A single-agent fusion of human IL-2 and anti-IL-2 antibody that selectively expands regulatory T cellsCommun BiolMarch 9, 2024Yuan Lin, Xue Wang, Yuhao Qin, Chengpan Wang, Tang Zhou, Long Zhang, Lu Su, Wenming Ren, Cheng Liaowere used to make anti-human IgG (Fc) chip for the affinity detection of human IL-2 (Sino Biological, GMP-11848-HNAE) with SD-01. SD-01 in HBS-EP+ buffer (Cytiva, BR100669, 33372) was injected over the chip surface for

(7) PRMT2 promotes HIV-1 latency by preventing nucleolar exit and phase separation of Tat into the Super Elongation ComplexNature CommunicationsNovember 10, 2023Jiaxing Jin, Hui Bai, Han Yan, Ting Deng, Tianyu Li, Ruijing Xiao, Lina Fan, Xue Bai, Hanhan Ning, Zhe Liu, et al.SH30406.05), 2.0 mM L-glutamine, and 1% penicillin/ streptomycin and IL-2 (100 U/ml, Sino Biological, GMP-11848-HNAE). Lentivirus production and infection For the preparation of pLKO and pSin-based lentivirus, corresponding

(8) Characterization of the Therapeutic Effects of Novel Chimeric Antigen Receptor T Cells Targeting CD38 on Multiple MyelomaFrontiers in oncologyJanuary 1, 2021Li X, Feng Y, Shang F, Yu Z, Wang T, Zhang J, Song Z, Wang P, Shi B, Wang J.soluble anti-CD3, clone OKT3 (Sino Biological, GMP-10977-H001) and 100 U/mL IL-2 (Sino Biological, GMP-11848-HNAE) and then cultured at 37°C in a 5% CO2 incubator for 48 hours. T cell growth medium was composed of

(9) Competition between PAF1 and MLL1/COMPASS confers the opposing function of LEDGF/p75 in HIV latency and proviral reactivationScience advancesMay 1, 2020Gao R, Bao J, Yan H, Xie L, Qin W, Ning H, Huang S, Cheng J, Zhi R, Li Z, et al.transcription during HIV latency reversal as well. SCIENCE ADVANCES | RESEARCH ARTICLE (Sino Biological, GMP-11848-HNAE) for 72 hours followed by transduction with pseudotyped HIV viruses. At day 10, latently infected and

(10) TGF-β inhibition via CRISPR promotes the long-term efficacy of CAR T cells against solid tumorsJCI insightFebruary 27, 2020Tang N, Cheng C, Zhang X, Qiao M, Li N, Mu W, Wei XF, Han W, Wang H.

(11) CD137 ligand feedback upregulates PD-L1 expression on lung cancer via T cell production of IFN-γThoracic cancerDecember 1, 2019Wang H, Yan Z, Hao J, Yang B, Wang J, Yi L, Wang X, Li S, Zhang H, Zhang S.

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Human Interleukin-2 / IL-2 Protein

Human Interleukin-2 / IL-2 Protein from Sino Biological, Inc.

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Sino Biological, Inc.

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Human Interleukin-2 / IL-2 Protein from Sino Biological, Inc.

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