VHL/ELOB/ELOC/CUL2/RBX1 Complex Protein E3-655-025 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemVHL/ELOB/ELOC/CUL2/RBX1 Complex Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $603.00Supplier Page View Company Product Page
Catalog NumberE3-655-025
Size25 ug
ApplicationsBioactivity
Conjugate/TagUnconjugated
FormatSupplied as a 0.2 µm filtered solution in HEPES, NaCl, DTT and Glycerol
SpeciesHuman
Molecule NameVHL/ELOB/ELOC/CUL2/RBX1 Complex
Source/Expression SystemSf 21 (baculovirus)-derived Recombinant Human Elongin B/Elongin C/VHL/CUL2/RBX1, CF
NCBI Full Gene Namevon Hippel-Lindau tumor suppressor, cullin 2, elongin C, ring-box 1, elongin B
NCBI Gene AliasesVHL1, pVHL, SIII, RNF75, TCEB2, TCEB1, ROC1, RCA1, HRCA1, BA554C12.1
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -70 °C as supplied. 3 months, -70 °C under sterile conditions after opening
Purity>90%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain

Specifications/Features

Available conjugates: Sizes Available: 25 ug

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) PHD3-VHL axis controls HIV-2 infection through oxygen-dependent hydroxylation and degradation of VpxPLoS PathogJune 16, 2025Kei Miyakawa, Kiho Tanaka, Yoko Ino, Yayoi Kimura, Taichi Kameya, Fuminori Mizukoshi, Mayuko Nishi, Masaru Yokoyama, Jun Nakabayashi, Masako Nomaguchi, et al.(Merck, #SRP6147), 1 µM UbcH5a (R&D Systems, #E2-616), 100 nM EloB/EloC/VHL/CUL2/RBX1 (R&D Systems, #E3-655–025), 5 µM ubiquitin (Merck, #U5507), 2.5 mM MgATP solution (R&D Systems, #B-20), and 1x E3 Ligase Reaction

(2) Bivalent target-binding bioPROTACs induce potent degradation of oncogenic SHP2The Journal of biological chemistrySeptember 1, 2024Hoffman M, Krum D, Wittrup KD.

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VHL/ELOB/ELOC/CUL2/RBX1 Complex Protein

VHL/ELOB/ELOC/CUL2/RBX1 Complex Protein

VHL/ELOB/ELOC/CUL2/RBX1 Complex Protein

VHL/ELOB/ELOC/CUL2/RBX1 Complex Protein from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (2)

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VHL/ELOB/ELOC/CUL2/RBX1 Complex Protein from R&D Systems, a Bio-Techne Brand

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