Recombinant Human Elongin B/Elongin C/VHL Complex, CF E3-600-050 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human Elongin B/Elongin C/VHL Complex, CF
CompanyR&D Systems, a Bio-Techne Brand
Price $631.00Supplier Page View Company Product Page
Catalog NumberE3-600-050
Purity>95%, by SDS-PAGE under reducing conditions and visualized by Colloidal Coomassie® Blue stain
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 6 months from date of receipt, -70 °C as supplied. 3 months, -70 °C under sterile conditions after opening
NCBI Gene AliasesVHL1, pVHL, SIII, TCEB2, TCEB1, RCA1, HRCA1
NCBI Full Gene Namevon Hippel-Lindau tumor suppressor, elongin C, elongin B
Source/Expression SystemSf 21 (baculovirus)-derived Recombinant Human Elongin B/Elongin C/VHL Complex, CF
Molecule NameELOB/ELOC/VHL Complex
SpeciesHuman
Molecular Weight24 kDa (VHL), 13.1 kDa (ELOB), 12.8 kDa (ELOC)
FormatSupplied as a solution in HEPES, NaCl, DTT and Glycerol
Conjugate/TagUnconjugated
ApplicationsBioactivity
Size50 ug

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(1) Rational screening for cooperativity in small-molecule inducers of protein-protein associationsbioRxiv : the preprint server for biologyMay 24, 2023Liu S, Tong B, Mason JW, Ostrem JM, Tutter A, Hua BK, Tang SA, Bonazzi S, Briner K, Berst F, et al.

(2) Bridged Proteolysis Targeting Chimera (PROTAC) Enables Degradation of Undruggable TargetsJournal of the American Chemical SocietyDecember 14, 2022Xiong Y, Zhong Y, Yim H, Yang X, Park KS, Xie L, Poulikakos PI, Han X, Xiong Y, Chen X, et al.

Recombinant Human Elongin B/Elongin C/VHL Complex, CF from R&D Systems, a Bio-Techne Brand