DLL4 Fc Chimera Protein 10185-D4-050 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemDLL4 Fc Chimera Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $420.00Supplier Page View Company Product Page
Catalog Number10185-D4-050
Size50 ug
ApplicationsBioactivity
Conjugate/TagUnconjugated
FormatLyophilized from a 0.2 µm filtered solution in PBS
Purity>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Molecular WeightObserved: 88-98 kDa, under reducing conditions
Theoretical: 81 kDa
SpeciesHuman
Molecule NameDLL4
Source/Expression SystemHEK293-derived Recombinant Human DLL4 Fc Chimera Protein, CF
NCBI Full Gene Namedelta like canonical Notch ligand 4
NCBI Gene Aliaseshdelta2, delta4, AOS6
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Sizes Available: 50 ug

Add to Compare List

R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) The Notch1 intracellular domain orchestrates mechanotransduction of fluid shear stressbioRxiv : the preprint server for biologyJuly 14, 2025Singh T, Jacobs KA, Polacheck WJ, Kutys ML.

(2) Diversity in Notch ligand-receptor signaling interactionseLifeJanuary 3, 2025Kuintzle R, Santat LA, Elowitz MB.10,184-DL-050", "Peptide, recombinant protein",Recombinant Human DLL4 Fc Chimera Protein,Bio-Techne/R&D Systems,Cat# 10185-D4-050, "Peptide, recombinant protein",Recombinant Human Jag1 Fc Chimera Protein,Bio-Techne/R&D Systems,Cat#

(3) Drivers of heterogeneity in synovial fibroblasts in rheumatoid arthritisNature immunologyJuly 1, 2023Smith MH, Gao VR, Periyakoil PK, Kochen A, DiCarlo EF, Goodman SM, Norman TM, Donlin LT, Leslie CS, Rudensky AY.

(4) A Notch/IL-21 signaling axis primes bone marrow T cell progenitor expansionJCI insightMay 9, 2022Sottoriva K, Paik NY, White Z, Bandara T, Shao L, Sano T, Pajcini KV.

(5) Periosteum-derived podoplanin-expressing stromal cells regulate nascent vascularization during epiphyseal marrow developmentThe Journal of biological chemistryMay 1, 2022Tamura S, Mukaide M, Katsuragi Y, Fujii W, Odaira K, Suzuki N, Tsukiji N, Okamoto S, Suzuki A, Kanematsu T, et al.

(6) NOTCH1 Intracellular Domain and the Tumor Microenvironment as Prognostic Markers in HNSCCCancersFebruary 21, 2022Schmidl B, Siegl M, Boxberg M, Stögbauer F, Jira D, Winter C, Stark L, Pickhard A, Wollenberg B, Wirth M.

(7) NOTCH3-targeted antibody drug conjugates regress tumors by inducing apoptosis in receptor cells and through transendocytosis into ligand cellsCell reports. MedicineMay 18, 2021Geles KG, Gao Y, Giannakou A, Sridharan L, Yamin TT, Zhang J, Karim R, Bard J, Piche-Nicholas N, Charati M, et al.hour at room temperature with 2 μg/mL of recombinant human DLL4 Fc chimera protein (R&D Systems, # 10185-D4-050) or left uncoated and cultured overnight in complete growth medium according to ATCC instructions. NOTCH3-targeted

(8) Notch signalling drives synovial fibroblast identity and arthritis pathologyNatureJune 1, 2020Wei K, Korsunsky I, Marshall JL, Gao A, Watts GFM, Major T, Croft AP, Watts J, Blazar PE, Lange JK, et al.

Be the First to Write a Review!

DLL4 Fc Chimera Protein

DLL4 Fc Chimera Protein

DLL4 Fc Chimera Protein

DLL4 Fc Chimera Protein

DLL4 Fc Chimera Protein

DLL4 Fc Chimera Protein from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (8)

Reviews

DLL4 Fc Chimera Protein from R&D Systems, a Bio-Techne Brand

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map