Human IGF1 / IGF-I Protein 10598-HNAE from Sino Biological, Inc.

Product Specs
ItemHuman IGF1 / IGF-I Protein
CompanySino Biological, Inc.
Price $58.00Supplier Page View Company Product Page
Catalog Number10598-HNAE
Activity1.Immobilized Recombinant Human IGF1 / IGF-I Protein (Cat: 10598-HNAE) at 2 µg/mL (100 µL/well) can bind Recombinant Human IGFBP4 Protein (His Tag) (Cat: 10967-H08H), the EC50 is 40-130 ng/mL. 2. Measured in a serum-free cell proliferation assay using MCF-7 human breast cancer cells. The ED50 for this effect is typically 3.5-14 ng/mL. 3.Human breast cancer organoids were cultured with FGF7(Cat#10210-H07E), RSPO1(Cat#11083-HNAS), IGF1(Cat#10598-HNAE), EGF(Cat#50482-MNCH), NRG1 Beta 1(Cat#11609-H01H), NOG(Cat#50688-M02H). (Routinely tested). Data provided by D1 Medical Technology. 4.Human breast organoids were cultured with IGF1(Cat#10598-HNAE), NRG1 Beta 1(Cat#11609-H01H). (Routinely tested). Data provided by D1 Medical Technology. 5.Human ovarian organoids were cultured with IGF1(Cat#10598-HNAE), NRG1 Beta 1(Cat#11609-H01H), RSPO1(Cat#11083-HNAS), EGF(Cat#50482-MNCH), NOG(Cat#50688-M02H). (Routinely tested). Data provided by D1 Medical Technology. 6.Western blot analysis of extracts from serum-starved MCF7, untreated (line A); treated with IGF-1 (Cat# 10598-HNAE) (100 ng/mL, 30 min; +) (line B); treated with IGF-1 and lambda-phosphatase (line C) using Phospho-S6K1 (Thr389) rabbit monoclonal Antibody (Cat# 110396-R0001) at 1:5000 dilution(upper), or Anti-RPS6KB1 rabbit polyclonal antibody (Cat# 10099-T38) (lower) at 1:5000 dilution (Routinely tested)
Conjugate/TagUnconjugated
FormatLyophilized from sterile 30% Acetonitrile, 0.1% TFA
Purity≥ 95 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC
TypeRecombinant protein
Molecular WeightThe recombinant human IGF1 consists of 71 amino acids and has a calculated molecular mass of 7.8 KDa
SpeciesHuman
Molecule NameIGF1
Source/Expression SystemE. coli
NCBI Full Gene Nameinsulin like growth factor 1
NCBI Gene AliasesIGF, IGF-I, IGFI, MGF
Size100 µg

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) Beyond Small Molecules: Orchestrating Cell Fate with Engineered Water-Soluble Membrane ProteinsBiomoleculesApril 8, 2026Sebastian Valencia-Amores, Israel Davila Aleman, Timothy G. Jenkins, Dario Mizrachidays [32]. Differentiated C2C12 myotubes were either treated with 100 ng/mL IGF-1 (Sino Biological 10598-HNAE, Sino Biological, Houston TX, USA) for 72 h, 1 µM iDRIVE-GPR56 every 24 h for 72 h, or left untreated

(2) Sperm-Derived CircRNA-1572 Regulates Embryogenesis and Zygotic Genome Activation by Targeting CCNB2 via Bta-miR-2478-L-2Advanced science (Weinheim, Baden-Wurttemberg, Germany)May 1, 2025Wu Y, Wei Y, Li Y, Dou Y, Yang Y, Liu H, Wang X, Wang Z, Su J, Zhang Y, et al.Sino Biological, Beijing, China, 10014‐HNAE), 20 ng mL−1 insulin‐like growth factor 1 (IGF‐1, Sino Biological,10598‐HNAE), 20 ng mL−1 leukemia inhibitory factor (LIF, Sino Biological, 14890‐HNAH), and 10 ng mL−1 epidermal

(3) IGF-I protects porcine granulosa cells from hypoxia-induced apoptosis by promoting homologous recombination repair through the PI3K/AKT/E2F8/RAD51 pathwayFASEB journal : official publication of the Federation of American Societies for Experimental BiologyJanuary 1, 2024Liu Z, Feng C, Li C, He T, Wu G, Fu C, Li H, Shen M, Liu H.

(4) GALNT14-mediated O-glycosylation on PHB2 serine-161 enhances cell growth, migration and drug resistance by activating IGF1R cascade in hepatoma cellsCell Death DisNovember 14, 2022Yu-De Chu, Tan-Chi Fan, Ming-Wei Lai, Chau-Ting Yehmanufacturer’s instructions. Insulin-like growth factor-1 (IGF1) (SinoBiological, BDA, Beijing, China, Cat: 10598-HNAE) was supplemented to the medium at a final concentration of 50 ng/mL to improve the IGF1 Receptor (IGF1R)

(5) Visualization of Ligand-Bound Ectodomain Assembly in the Full-Length Human IGF-1 Receptor by Cryo-EM Single-Particle AnalysisStructure (London, England : 1993)May 5, 2020Zhang X, Yu D, Sun J, Wu Y, Gong J, Li X, Liu L, Liu S, Liu J, Wu Y, et al.

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Human IGF1 / IGF-I Protein

Human IGF1 / IGF-I Protein from Sino Biological, Inc.

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Sino Biological, Inc.

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Human IGF1 / IGF-I Protein from Sino Biological, Inc.

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