Recombinant Human BDNF Protein 248-BDB-050 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human BDNF Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $944.00Supplier Page View Company Product Page
Catalog Number248-BDB-050
FormatLyophilized from a 0.2 µm filtered solution in Sodium Citrate and NaCl with BSA as a carrier protein
Source/Expression SystemSf 21 (baculovirus)-derived Recombinant Human BDNF Protein
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution
NCBI Gene AliasesBULN2, ANON2
NCBI Full Gene Namebrain derived neurotrophic factor
Molecule NameBDNF
SpeciesHuman, Mouse, Rat, Canine, Equine
Molecular WeightObserved: 13-14 kDa, under reducing conditions.
Theoretical: 13.5 kDa
Purity>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Conjugate/TagUnconjugated
ApplicationsBioactivity
Size50 ug (also 5 ug, 10 ug, 250 ug, 1 mg)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Chemogenetic tuning reveals optimal MAPK signaling for cell-fate programmingCell ReportsSeptember 23, 2025Brittany A. Lende-Dorn, Jane C. Atkinson, Yunbeen Bae, Kate E. Gallowayproteins" RepSox(TGF-β inhibitor),Selleck Chemicals,Cat# S7223 Recombinant Human BDNF Protein,R&D Systems,Cat# 248-BDB-050 Recombinant Human CNTF Protein,R&D Systems,Cat# 257-NT-050 Recombinant Human GDNF Protein,R&D Systems,Cat#

(2) Specification of human brain regions with orthogonal gradients of WNT and SHH in organoids reveals patterning variations across cell linesCell stem cellJune 5, 2025Scuderi S, Kang TY, Jourdon A, Nelson A, Yang L, Wu F, Anderson GM, Mariani J, Tomasini L, Sarangi V, et al.

(3) Generation and long-term culture of human cerebellar organoids from pluripotent stem cellsNature protocolsJune 1, 2025Atamian A, Birtele M, Hosseini N, Quadrato G.

(4) Proliferation history and transcription factor levels drive direct conversion to motor neuronsCell SystemsApril 16, 2025Nathan B. Wang, Brittany A. Lende-Dorn, Adam M. Beitz, Patrick Han, Honour O. Adewumi, Timothy M. O’Shea, Kate E. Gallowayproteins" RepSox (TGF-β inhibitor),Selleck Chemicals,Cat#S7223 Recombinant Human BDNF Protein,R&D Systems,Cat#248-BDB-050 Recombinant Human CNTF Protein,R&D Systems,Cat#257-NT-050 Recombinant Human GDNF Protein,R&D Systems,Cat#212-GD-050 Recombinant

(5) Compact transcription factor cassettes generate functional, engraftable motor neurons by direct conversionCell SystemsApril 16, 2025Nathan B. Wang, Honour O. Adewumi, Brittany A. Lende-Dorn, Adam M. Beitz, Timothy M. O’Shea, Kate E. Gallowayproteins",, RepSox (TGF-β inhibitor),Selleck Chemicals,Cat#S7223 Recombinant Human BDNF Protein,R&D Systems,Cat#248-BDB-050 Recombinant Human CNTF Protein,R&D Systems,Cat#257-NT-050 Recombinant Human GDNF Protein,R&D Systems,Cat#212-GD-050 Recombinant

(6) Role of immature choroid plexus in the pathology of model mice and human iPSC-derived organoids with autism spectrum disorderCell reportsJanuary 28, 2025Tanabe M, Saito Y, Takasaki A, Nakano K, Yamamoto S, Suzuki C, Kawamura N, Hattori A, Oikawa M, Nagashima S, et al.

(7) Altered mitochondria-associated ER membrane (MAM) function shifts mitochondrial metabolism in amyotrophic lateral sclerosis (ALS)Nature communicationsJanuary 3, 2025Larrea D, Tamucci KA, Kabra K, Velasco KR, Yun TD, Pera M, Montesinos J, Agrawal RR, Paradas C, Smerdon JW, et al.

(8) Morphological diversification and functional maturation of human astrocytes in glia-enriched cortical organoid transplanted in mouse brainNature biotechnologyJanuary 1, 2025Wang M, Zhang L, Novak SW, Yu J, Gallina IS, Xu LL, Lim CK, Fernandes S, Shokhirev MN, Williams AE, et al.

(9) Toe1 promotes proliferation and differentiation of neural progenitor cellsHeliyonOctober 30, 2024Deng T, Wu X, Wang Y, Fan X, Hu B.

(10) Neuroprotective effects of intranasal extracellular vesicles from human platelet concentrates supernatants in traumatic brain injury and Parkinson's disease modelsJournal of biomedical scienceSeptember 5, 2024Delila L, Nebie O, Le NTN, Timmerman K, Lee DY, Wu YW, Chou ML, Buée L, Chou SY, Blum D, et al.

(11) KCNJ2 inhibition mitigates mechanical injury in a human brain organoid model of traumatic brain injuryCell stem cellApril 4, 2024Lai JD, Berlind JE, Fricklas G, Lie C, Urenda JP, Lam K, Sta Maria N, Jacobs R, Yu V, Zhao Z, et al.

(12) Secretome Analyses Identify FKBP4 as a GBA1-Associated Protein in CSF and iPS Cells from Parkinson's Disease Patients with GBA1 MutationsInternational journal of molecular sciencesJanuary 4, 2024Kojima R, Paslawski W, Lyu G, Arenas E, Zhang X, Svenningsson P.consisting of 20 ng/mL brain-derived neurotrophic factor (BDNF, R&D Systems, NE Minneapolis, MN, USA, 248-BDB-050), 20 ng/mL glial cell line-derived neurotrophic factor (GDNF, R&D Systems, 212-GD-050), 1 ng/mL transforming

(13) Human cerebellar organoids with functional Purkinje cellsCell stem cellJanuary 4, 2024Atamian A, Birtele M, Hosseini N, Nguyen T, Seth A, Del Dosso A, Paul S, Tedeschi N, Taylor R, Coba MP, et al.proteins" Accutase,Sigma,07922 AmphoB,Gibco,15290018 Apo-transferrin,Sigma,T1147-100MG BDNF,R&D Systems,248-BDB-050 BrainPhys Optimized Medium,STEMCELL Technologies,05796 Bovine Serum Albumin (BSA),Sigma,A0281 B-27

(14) Inositol trisphosphate and ryanodine receptor signaling distinctly regulate neurite pathfinding in response to engineered micropatterned surfacesPloS oneJanuary 1, 2024Vecchi JT, Rhomberg M, Allan Guymon C, Hansen MR.

(15) Disrupting cellular memory to overcome drug resistanceNature communicationsNovember 6, 2023Harmange G, Hueros RAR, Schaff DL, Emert B, Saint-Antoine M, Kim LC, Niu Z, Nellore S, Fane ME, Alicea GM, et al.

(16) Analysis of proteome-wide degradation dynamics in ALS SOD1 iPSC-derived patient neurons reveals disrupted VCP homeostasisCell reportsOctober 31, 2023Tsioras K, Smith KC, Edassery SL, Garjani M, Li Y, Williams C, McKenna ED, Guo W, Wilen AP, Hark TJ, et al.

(17) BDNF-loaded PDADMAC-heparin multilayers: a novel approach for neuroblastoma cell studyScientific reportsOctober 20, 2023Dąbkowska M, Stukan I, Kowalski B, Donerowicz W, Wasilewska M, Szatanik A, Stańczyk-Dunaj M, Michna A.

(18) Multiomic prediction of therapeutic targets for human diseases associated with protein phase separationProceedings of the National Academy of Sciences of the United States of AmericaOctober 3, 2023Lim CM, González Díaz A, Fuxreiter M, Pun FW, Zhavoronkov A, Vendruscolo M.

(19) A branching model of lineage differentiation underpinning the neurogenic potential of enteric gliaNature communicationsSeptember 22, 2023Laddach A, Chng SH, Lasrado R, Progatzky F, Shapiro M, Erickson A, Sampedro Castaneda M, Artemov AV, Bon-Frauches AC, Amaniti EM, et al.

(20) The Impact of Serum Protein Adsorption on PEGylated NT3-BDNF Nanoparticles-Distribution, Protein Release, and Cytotoxicity in a Human Retinal Pigmented Epithelial Cell ModelPharmaceuticsAugust 30, 2023Dąbkowska M, Kosiorowska A, Machaliński B.

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Recombinant Human BDNF Protein

BDNF Protein

BDNF Protein

BDNF Protein

BDNF Protein

Recombinant Human BDNF Protein from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Human BDNF Protein from R&D Systems, a Bio-Techne Brand

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