Neuregulin-1/NRG1 Protein 9875-NR-050 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemNeuregulin-1/NRG1 Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $449.00Supplier Page View Company Product Page
Catalog Number9875-NR-050
Size50 ug
ApplicationsBioactivity
Conjugate/TagUnconjugated
Purity>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Molecular WeightObserved: 42-49 kDa, reducing conditions
Theoretical: 26 kDa
SpeciesMouse
Molecule NameNeuregulin-1/NRG1
Source/Expression SystemNS0-derived Recombinant Mouse Neuregulin-1/NRG1 Protein, CF
FormatLyophilized from a 0.2 µm filtered solution in PBS
Storage12 months from date of receipt, <= -20 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, <= -20 °C under sterile conditions after reconstitution
NCBI Full Gene Nameneuregulin 1
NCBI Gene AliasesARIA, GGF, GGF2, HGL, HRG, HRG1, HRGA, MST131, MSTP131, NDF, NRG1-IT2, SMDF

Specifications/Features

Available conjugates: Sizes Available: 50 ug

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Schwann cell Lrp1 deletion drives trigeminal neuron sensitization and orofacial pain by modulating mitochondrial function and TRPV1/TRPA1 activityJ Headache PainDecember 22, 2025Zhiting Gong, Morgan Zhang, Naijiang Liu, Kesava Asam, Stefano Martellucci, Bradley Aouizerat, Wendy Campana, Yi YeF6886/344282), and recombinant human Neuregulin-1 (NRG1, 1 nM; R&D Systems™, Bio-Techne, USA; cat. no. 9875-NR-050), and plated onto poly-D-lysine/laminin–coated culture dishes (poly-D-lysine: Gibco, USA, cat. no. A3890401;

(2) The Brain-Penetrant Pan-ErbB Inhibitor Poziotinib Effectively Targets HER2+ Breast Cancer Brain MetastasesCancer researchApril 15, 2025Ippolitov D, Lin YH, Spence J, Glogowska A, Thanasupawat T, Beiko J, Del Bigio MR, Xu X, Wang AQ, Williams D, et al.

(3) Multi-culture label-free quantitative cell migration sensing with single-cell precisionBiomedical Optics ExpressJanuary 1, 2025Piotr Arcab, Mikołaj Rogalski, Marcin Marzejon, Piotr Rogujski, Luiza Stanaszek, Maciej Trusiakon the T25 culture dishes (Falcon) until confluent. Upon seeding, recombinant neuregulin-1 (Cat. No. 9875-NR-050, R&D Systems, Minneapolis, MN, USA) was added in two different concentrations - 10 and 50 ng/ml of medium

(4) Multi-culture label-free quantitative cell migration sensing with single-cell precisionBiomed Opt ExpressDecember 20, 2024Piotr Arcab, Mikołaj Rogalski, Marcin Marzejon, Piotr Rogujski, Luiza Stanaszek, Maciej Trusiakon the T25 culture dishes (Falcon) until confluent. Upon seeding, recombinant neuregulin-1 (Cat. No. 9875-NR-050, R&D Systems, Minneapolis, MN, USA) was added in two different concentrations - 10 and 50 ng/ml of medium

(5) Collagen signaling and matrix stiffness regulate multipotency in glandular epithelial stem cells in miceNature communicationsDecember 18, 2024Jiang C, Centonze A, Song Y, Chrisnandy A, Tika E, Rezakhani S, Zahedi Z, Bouvencourt G, Dubois C, Van Keymeulen A, et al.

(6) Toxoplasma infection induces an aged neutrophil population in the CNS that is associated with neuronal protectionJournal of neuroinflammationAugust 2, 2024Bergersen KV, Kavvathas B, Ford BD, Wilson EH.

(7) N-cadherin directs the collective Schwann cell migration required for nerve regeneration through Slit2/3-mediated contact inhibition of locomotioneLifeApril 9, 2024Hoving JJA, Harford-Wright E, Wingfield-Digby P, Cattin AL, Campana M, Power A, Morgan T, Torchiaro E, Quereda V, Lloyd AC.

(8) Coordinate transcriptional regulation of ErbB2/3 by C-terminal binding protein 2 signals sensitivity to ErbB2 inhibition in pancreatic adenocarcinomaOncogenesisNovember 10, 2023Chougoni KK, Park H, Damle PK, Mason T, Cheng B, Dcona MM, Szomju B, Dozmorov MG, Idowu MO, Grossman SR.

(9) Mammary duct luminal epithelium controls adipocyte thermogenic programmeNatureAugust 1, 2023Patel S, Sparman NZR, Arneson D, Alvarsson A, Santos LC, Duesman SJ, Centonze A, Hathaway E, Ahn IS, Diamante G, et al.

(10) Immune stimulation recruits a subset of pro-regenerative macrophages to the retina that promotes axonal regrowth of injured neuronsActa neuropathologica communicationsMay 24, 2023Andries L, Kancheva D, Masin L, Scheyltjens I, Van Hove H, De Vlaminck K, Bergmans S, Claes M, De Groef L, Moons L, et al.

(11) Cellular mechanisms of heterogeneity in NF2-mutant schwannomaNature communicationsMarch 21, 2023Chiasson-MacKenzie C, Vitte J, Liu CH, Wright EA, Flynn EA, Stott SL, Giovannini M, McClatchey AI.

(12) Neuregulin-1 signaling regulates cytokines and chemokines expression and secretion in granulosa cellJournal of ovarian researchJuly 26, 2022Banerjee S, Mishra S, Xu W, Thompson WE, Chowdhury I.

(13) Budding epithelial morphogenesis driven by cell-matrix versus cell-cell adhesionCellJuly 8, 2021Wang S, Matsumoto K, Lish SR, Cartagena-Rivera AX, Yamada KM.to each well. This culture media was modified from (Nakao et al., 2017). 20 ng/mL NRG1 (R&D Systems, 9875-NR-050) was also included in the 2× culture mix in earlier experiments, but it was omitted later as follow-up studies

(14) Epithelium-derived Indian Hedgehog restricts stromal expression of ErbB family members that drive colonic tumor cell proliferationOncogeneMarch 1, 2021Westendorp F, Karpus ON, Koelink PJ, Vermeulen JLM, Meisner S, Koster J, Büller NVJA, Wildenberg ME, Muncan V, van den Brink GR.

(15) Thrombomodulin facilitates peripheral nerve regeneration through regulating M1/M2 switchingJournal of neuroinflammationAugust 14, 2020Huang TC, Wu HL, Chen SH, Wang YT, Wu CC.

(16) Class IIa histone deacetylases link cAMP signaling to the myelin transcriptional program of Schwann cellsThe Journal of cell biologyApril 2, 2018Gomis-Coloma C, Velasco-Aviles S, Gomez-Sanchez JA, Casillas-Bajo A, Backs J, Cabedo H.

(17) Injectable hydrogels of optimized acellular nerve for injection in the injured spinal cordBiomedical materials (Bristol, England)March 21, 2018Cornelison RC, Gonzalez-Rothi EJ, Porvasnik SL, Wellman SM, Park JH, Fuller DD, Schmidt CE.

(18) "Axon-derived PACSIN1 binds to the Schwann cell survival receptor, LRP1, and transactivates TrkC to promote gliatrophic activities"GliaJanuary 1, 0001"Martellucci S, Flütsch A, Carter M, Norimoto M, Pizzo D, Mantuano E, Sadri M, Wang Z, Chillin-Fuentes D, Rosenthal SB, et al."NJ, USA); Neurotrophin-3 (NT-3) (#267-N3-005, R&D System, Minneapolis, USA) or Neuregulin 1 (NRG1) (#9875-NR-050, R&D System, Minneapolis, USA). In some cases, SCs were pretreated with MK801 (1 μM) (#27213, Cayman Chemical

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Neuregulin-1/NRG1 Protein

Neuregulin-1/NRG1 Protein

Neuregulin-1/NRG1 Protein

Neuregulin-1/NRG1 Protein

Neuregulin-1/NRG1 Protein

Neuregulin-1/NRG1 Protein from R&D Systems, a Bio-Techne Brand

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (18)

Reviews

Neuregulin-1/NRG1 Protein from R&D Systems, a Bio-Techne Brand

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