Description
Description: IMPAD1 Mouse Recombinant produced in Sf9 Baculoviruscells is a single, glycosylated polypeptide chain containing 332 amino acids (34-356a.a.)and having a molecular mass of 36.2kDa. (Molecular size on SDS-PAGE will appearat approximately 28-40kDa). IMPAD1 is expressed with a6 amino acid His tag at C-Terminus and purified by proprietary chromatographictechniques.
Introduction: Inositol monophosphatase 3 (IMPAD1) belongs to the inositol monophosphatase family. IMPAD1 is restricted to the Golgi apparatus and catalyzes the hydrolysis of phosphoadenosine phosphate (PAP) to adenosine monophosphate (AMP). IMPAD1 gene mutations cause the GRAPP type chondrodysplasia with joint dislocations, and a pseudogene of the IMPAD1 gene is located on the long arm of chromosome 1