Recombinant Human IL-18/IL-1F4 Protein 9124-IL-050 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Human IL-18/IL-1F4 Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $391.00Supplier Page View Company Product Page
Catalog Number9124-IL-050
FormatLyophilized from a 0.2 µm filtered solution in PBS and DTT with BSA as a carrier protein
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution
NCBI Gene AliasesIL-1g, IGIF, IL-18, IL1F4
NCBI Full Gene Nameinterleukin 18
Source/Expression SystemE. coli-derived Recombinant Human IL-18/IL-1F4 Protein
Molecule NameIL-18/IL-1F4
SpeciesHuman
Molecular WeightObserved: 18 kDa, reducing conditions
Theoretical: 18 kDa
Purity>95%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Conjugate/TagUnconjugated
ApplicationsBioactivity
Size50 ug (also 10 ug, 500 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Migration arrest and transendothelial trafficking of human pathogenic-like Th17 cells are mediated by differentially positioned chemokinesNature communicationsFebruary 26, 2025Parween F, Singh SP, Kathuria N, Zhang HH, Ashida S, Otaizo-Carrasquero FA, Shamsaddini A, Gardina PJ, Ganesan S, Kabat J, et al.

(2) Alveolar hypoxia induces organ-specific inflammasome-related inflammation in male mouse lungsPhysiological reportsJuly 1, 2024Udjus C, Halvorsen B, Kong XY, Sagen EL, Martinsen M, Yang K, Løberg EM, Christensen G, Skjønsberg OH, Larsen KO.

(3) Regulation of HHLA2 expression in kidney cancer and myeloid cellsBMC cancerOctober 27, 2023Shigemura T, Perrot N, Huang Z, Bhatt RS, Sheshdeh AB, Ahmar NE, Ghandour F, Signoretti S, McDermott DF, Freeman GJ, et al.

(4) TNFα induced by DNA-sensing in macrophage compromises retinal pigment epithelial (RPE) barrier functionScientific reportsSeptember 2, 2023Twarog M, Schustak J, Xu Y, Coble M, Dolan K, Esterberg R, Huang Q, Saint-Geniez M, Bao Y.

(5) Chemokine positioning determines mutually exclusive roles for their receptors in extravasation of pathogenic human T cellsbioRxiv : the preprint server for biologyFebruary 13, 2023Parween F, Singh SP, Zhang HH, Kathuria N, Otaizo-Carrasquero FA, Shamsaddini A, Gardina PJ, Ganesan S, Kabat J, Lorenzi HA, et al.

(6) Differential IL18 signaling via IL18 receptor and Na-Cl co-transporter discriminating thermogenesis and glucose metabolism regulationNature communicationsDecember 8, 2022Zhang X, Luo S, Wang M, Cao Q, Zhang Z, Huang Q, Li J, Deng Z, Liu T, Liu CL, et al.were starved for 8 hrs, followed by treating the cells with 0, 10 or 100 ng/mL recombinant human IL18 (9124-IL-050, R&D Systems) for 24 h. Flow cytometry SVFs were isolated by collagenase digestion from EAT, SAT,

(7) In vivo G-CSF treatment activates the GR-SOCS1 axis to suppress IFN-γ secretion by natural killer cellsCell reportsSeptember 13, 2022Zhao X, Peng T, Cao X, Hou Y, Li R, Han T, Fan Z, Zhao M, Chang Y, Chen H, et al.

(8) DLL4 and VCAM1 enhance the emergence of T cell-competent hematopoietic progenitors from human pluripotent stem cellsScience advancesAugust 26, 2022Michaels YS, Edgar JM, Major MC, Castle EL, Zimmerman C, Yin T, Hagner A, Lau C, Hsu HH, Ibañez-Rios MI, et al.

(9) Imprint of unconventional T-cell response in acute hepatitis C persists despite successful early antiviral treatmentEuropean journal of immunologyMarch 1, 2022Du Y, Khera T, Strunz B, Deterding K, Todt D, Woller N, Engelskircher SA, Hardtke S, Port K, Ponzetta A, et al.

(10) Selectivity Profile of the Tyrosine Kinase 2 Inhibitor Deucravacitinib Compared with Janus Kinase 1/2/3 InhibitorsDermatology and TherapyOctober 1, 2021Anjaneya Chimalakonda et al.recombinant human IL-12 (catalog no. 200-12; PeproTech US) plus 10 ng/mL of recombinant human IL-18 (catalog no. 9124-IL-050; R&D Systems, Inc, Minneapolis, MN) overnight at 37 °C in a carbon dioxide incubator. Blood was centrifuged

(11) Mucosal-Associated Invariant T (MAIT) Cells Are Highly Activated and Functionally Impaired in COVID-19 PatientsVirusesFebruary 3, 2021Deschler S, Kager J, Erber J, Fricke L, Koyumdzhieva P, Georgieva A, Lahmer T, Wiessner JR, Voit F, Schneider J, et al.

(12) Human Thymic CD10⁺ PD-1⁺ Intraepithelial Lymphocyte Precursors Acquire Interleukin-15 Responsiveness at the CD1a^- CD95⁺ CD28^- CCR7^- Developmental StageInternational journal of molecular sciencesNovember 20, 2020Billiet L, Goetgeluk G, Bonte S, De Munter S, De Cock L, Pille M, Ingels J, Jansen H, Weening K, Van Nieuwerburgh F, et al.

(13) Boosting NAD level suppresses inflammatory activation of PBMCs in heart failureThe Journal of clinical investigationNovember 2, 2020Zhou B, Wang DD, Qiu Y, Airhart S, Liu Y, Stempien-Otero A, O'Brien KD, Tian R.

(14) Inflammatory Signals Induce AT2 Cell-Derived Damage-Associated Transient Progenitors that Mediate Alveolar RegenerationCell stem cellSeptember 3, 2020Choi J, Park JE, Tsagkogeorga G, Yanagita M, Koo BK, Han N, Lee JH.

(15) Metabolic Reprograming via Deletion of CISH in Human iPSC-Derived NK Cells Promotes In Vivo Persistence and Enhances Anti-tumor ActivityCell stem cellAugust 6, 2020Zhu H, Blum RH, Bernareggi D, Ask EH, Wu Z, Hoel HJ, Meng Z, Wu C, Guan KL, Malmberg KJ, et al.

(16) The TL1A-DR3 Axis Selectively Drives Effector Functions in Human MAIT CellsJournal of immunology (Baltimore, Md. : 1950)December 1, 2019Sattler A, Thiel LG, Ruhm AH, Souidi N, Seifert M, Herberth G, Kotsch K.

(17) CD161 contributes to prenatal immune suppression of IFNγ-producing PLZF+ T cellsThe Journal of clinical investigationMay 30, 2019Halkias J, Rackaityte E, Hillman SL, Aran D, Mendoza VF, Marshall LR, MacKenzie TC, Burt TD.cells were activated with 50 μg IL- 12 (PeproTech, catalog 200-12) and IL-18 (R&D Systems, catalog 9124IL-050) at 50 ng/mL for 16–20 hours at 37°C in 4% O2, and Brefeldin A was added for the last 4 hours. After

(18) Tumor-infiltrating mucosal-associated invariant T (MAIT) cells retain expression of cytotoxic effector moleculesOncotargetApril 19, 2019Sundström P, Szeponik L, Ahlmanner F, Sundquist M, Wong JSB, Lindskog EB, Gustafsson B, Quiding-Järbrink M.

(19) Induction of antiinflammatory purinergic signaling in activated human iNKT cellsJCI insightSeptember 6, 2018Yu JC, Lin G, Field JJ, Linden J.

(20) An anti-TL1A antibody for the treatment of asthma and inflammatory bowel diseasemAbsMay 1, 2018Clarke AW, Poulton L, Shim D, Mabon D, Butt D, Pollard M, Pande V, Husten J, Lyons J, Tian C, et al.

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IL-18/IL-1F4 Protein

IL-18/IL-1F4 Protein

IL-18/IL-1F4 Protein

IL-18/IL-1F4 Protein

IL-18/IL-1F4 Protein

Recombinant Human IL-18/IL-1F4 Protein from R&D Systems, a Bio-Techne Brand

Description

R&D Systems, a Bio-Techne Brand

Citations (27)

Reviews

Recombinant Human IL-18/IL-1F4 Protein from R&D Systems, a Bio-Techne Brand

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