Recombinant Mouse IL-18/IL-1F4 Protein 9139-IL-050 from R&D Systems, a Bio-Techne Brand

Product Specs
ItemRecombinant Mouse IL-18/IL-1F4 Protein
CompanyR&D Systems, a Bio-Techne Brand
Price $391.00Supplier Page View Company Product Page
Catalog Number9139-IL-050
FormatLyophilized from a 0.2 µm filtered solution in PBS, EDTA and DTT with BSA as a carrier protein
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution
NCBI Gene AliasesIgif, Il-18
NCBI Full Gene Nameinterleukin 18
Source/Expression SystemE. coli-derived Recombinant Mouse IL-18/IL-1F4 Protein
Molecule NameIL-18/IL-1F4
SpeciesMouse
Molecular WeightObserved: 17 kDa, reducing conditions
Theoretical: 18 kDa
Purity>90%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Conjugate/TagUnconjugated
ApplicationsBioactivity
Size50 ug (also 10 ug, 500 ug)

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Organ injury in systemic autoimmunity is mediated by stem-like CD8+ T cells arising from tissue-draining lymph nodesImmunityApril 20, 2026Jafar Al Souz, Yulong Wei, Can Cui, Rihao Qu, Jin-Young Choi, Fang Wang, Steven J. Moioffer, Julia Barrett, Irene Chernova, Manvitha Nadella, et al.carrier,R&D Systems,Ca#447-ML-010 Recombinant Mouse IL-18/IL-1F4 Protein with carrier,R&D Systems,Cat#9139-IL-050 Recombinant Mouse IL-21 Protein with carrier,R&D Systems,Cat#594-ML-025 Universal Type I IFN Protein,R&D Systems

(2) Type 1 immunity enables neonatal thymic ILC1 productionScience advancesJanuary 19, 2024Tougaard P, Ruiz Pérez M, Steels W, Huysentruyt J, Verstraeten B, Vetters J, Divert T, Gonçalves A, Roelandt R, Takahashi N, et al.

(3) An IL-4 signalling axis in bone marrow drives pro-tumorigenic myelopoiesisNatureJanuary 1, 2024LaMarche NM, Hegde S, Park MD, Maier BB, Troncoso L, Le Berichel J, Hamon P, Belabed M, Mattiuz R, Hennequin C, et al.

(4) Cytokine-Mediated Degradation of the Transcription Factor ERG Impacts the Pulmonary Vascular Response to Systemic Inflammatory ChallengebioRxiv : the preprint server for biologyFebruary 11, 2023Schafer CM, Martin-Almedina S, Kurylowicz K, Dufton N, Osuna-Almagro L, Wu ML, Johnson CF, Shah AV, Haskard DO, Buxton A, et al.

(5) In vivo G-CSF treatment activates the GR-SOCS1 axis to suppress IFN-γ secretion by natural killer cellsCell reportsSeptember 13, 2022Zhao X, Peng T, Cao X, Hou Y, Li R, Han T, Fan Z, Zhao M, Chang Y, Chen H, et al.

(6) ILC precursors differentiate into metabolically distinct ILC1-like cells during Mycobacterium tuberculosis infectionCell reportsApril 19, 2022Corral D, Charton A, Krauss MZ, Blanquart E, Levillain F, Lefrançais E, Sneperger T, Vahlas Z, Girard JP, Eberl G, et al.interleukin-12),R&D Systems,Cat# 419-ML-050 rmIL-18 (recombinant mouse interleukin-18),R&D Systems,Cat# 9139-IL-050 rmIL-7 (recombinant mouse interleukin-7),R&D Systems,Cat# 407-ML-025 rmIL-2 (recombinant mouse interleukin-2),R&D Systems

(7) IL-22 initiates an IL-18-dependent epithelial response circuit to enforce intestinal host defenceNature communicationsFebruary 15, 2022Chiang HY, Lu HH, Sudhakar JN, Chen YW, Shih NS, Weng YT, Shui JW.

(8) Interleukin-18 accelerates cardiac inflammation and dysfunction during ischemia/reperfusion injury by transcriptional activation of CXCL16Cellular signallingNovember 1, 2021Zhao G, Zhang H, Zhu S, Wang S, Zhu K, Zhao Y, Xu L, Zhang P, Xie J, Sun A, et al.

(9) Chronic stress physically spares but functionally impairs innate-like invariant T cellsCell reportsApril 13, 2021Rudak PT, Choi J, Parkins KM, Summers KL, Jackson DN, Foster PJ, Skaro AI, Leslie K, McAlister VC, Kuchroo VK, et al.214-14 Recombinant mouse IL-12p70,Peprotech,Cat # 210-12 Recombinant mouse IL-18,R&D Systems,Cat # 9139-IL-050 6-hydroxydopamine hydrobromide,Sigma-Aldrich,Cat # 162957 Corticosterone,Sigma-Aldrich,Cat # 27840 Hydrocortisone,Sigma-Aldrich,Cat

(10) ILC2s amplify PD-1 blockade by activating tissue-specific cancer immunityNatureMarch 1, 2020Moral JA, Leung J, Rojas LA, Ruan J, Zhao J, Sethna Z, Ramnarain A, Gasmi B, Gururajan M, Redmond D, et al.

(11) Bystander Activation of Pulmonary Trm Cells Attenuates the Severity of Bacterial Pneumonia by Enhancing Neutrophil RecruitmentCell reportsDecember 24, 2019Ge C, Monk IR, Pizzolla A, Wang N, Bedford JG, Stinear TP, Westall GP, Wakim LM.

(12) Caspase-11 Mediates Neutrophil Chemotaxis and Extracellular Trap Formation During Acute Gouty Arthritis Through Alteration of Cofilin PhosphorylationFrontiers in immunologyJanuary 1, 2019Caution K, Young N, Robledo-Avila F, Krause K, Abu Khweek A, Hamilton K, Badr A, Vaidya A, Daily K, Gosu H, et al.inflammatory mediators for 4 h. 20 ng/ml IL-1α, IL-1β, IL-18, and KC (R&D Systems, 400-ML-005, 401-ML-005, 9139-IL-050, and 453-KC-050), HMGB1 (eBioscience, 34-8401-82), 2.5 μg/ml Pam3CSK4 (tlrl-pms), 5 μg/ml poly(I:C)

(13) Polymicrobial sepsis influences NK-cell-mediated immunity by diminishing NK-cell-intrinsic receptor-mediated effector responses to viral ligands or infectionsPLoS pathogensOctober 1, 2018Jensen IJ, Winborn CS, Fosdick MG, Shao P, Tremblay MM, Shan Q, Tripathy SK, Snyder CM, Xue HH, Griffith TS, et al.

(14) Activin in acute pancreatitis: Potential risk-stratifying marker and novel therapeutic targetScientific reportsOctober 6, 2017Staudacher JJ, Yazici C, Carroll T, Bauer J, Pang J, Krett N, Xia Y, Wilson A, Papachristou G, Dirmeier A, et al.

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Recombinant Mouse IL-18/IL-1F4 Protein

IL-18/IL-1F4 Protein

IL-18/IL-1F4 Protein

IL-18/IL-1F4 Protein

IL-18/IL-1F4 Protein

Recombinant Mouse IL-18/IL-1F4 Protein from R&D Systems, a Bio-Techne Brand

R&D Systems, a Bio-Techne Brand

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Recombinant Mouse IL-18/IL-1F4 Protein from R&D Systems, a Bio-Techne Brand

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