Human IL17 / IL17A Protein 12047-HNAE from Sino Biological, Inc.

Product Specs
ItemHuman IL17 / IL17A Protein
CompanySino Biological, Inc.
Price $58.00Supplier Page View Company Product Page
Catalog Number12047-HNAE
Conjugate/TagUnconjugated
Purity≥ 95 % as determined by SDS-PAGE
TypeRecombinant protein
Molecular WeightThe recombinant human IL17A consists of 137 amino acids and predicts a molecular mass of 15.7 KDa
SpeciesHuman
Molecule NameIL17A
Source/Expression SystemE. coli
NCBI Full Gene Nameinterleukin 17A
NCBI Gene AliasesCTLA-8, CTLA8, IL-17, IL-17A, IL17, ILA17
Activity1.Measured by its ability to induce IL-6 secretion by NIH-3T3 mouse embryonic fibroblast cells in the presense of 20 ng/mL TNFα. The ED50 for this effect is 0.5-2.5 ng/mL. 2.Recombinant Human IL-17RA Protein, hFc Tag (Cat. No. 10895-H02H) captured on Protein A chip can bind Recombinant Human IL-17A Protein (Cat. No. 12047-HNAE) with an affinity constant of 0.190 nM as determined in an SPR assay (Biacore 8K) (Routinely tested). 3.Anti-IL17A (Research Grade Ixekiz*mab Biosimilar) captured on Protein A chip, can bind Recombinant Human IL-17A Protein (Cat. No. 12047-HNAE) with an affinity constant of 24.450 pM pM as determined in an SPR assay (Biacore T200) (Routinely tested). 4.Anti-IL17A (Research Grade Secukin*mab Biosimilar) captured on Protein A chip, can bind Recombinant Human IL-17A Protein (Cat. No. 12047-HNAE) with an affinity constant of 65.890 pM as determined in an SPR assay (Biacore T200) (Routinely tested)
FormatLyophilized from sterile PBS, pH 7.4
Size5 µg

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) Elevated SNHG15 empowers keratinocytes hyperproliferation through activation of STAT3/Cyclin D1 axis in psoriasisActa Pharmaceutica Sinica BOctober 17, 2025Lipeng Tang, Guanzhuo Li, Jiameng Chang, Haiyan Xian, Yanjie Liu, Luping Lin, Zixin Dai, Zhenting Liu, Xinmin Qiu, Bowen Zhang, et al.China). IL-6 (10395-HNAE), IL-1β (10139-HNAE), TNF-α (10602-HNAE), IL-22 (13059-HNAE), and IL-17A (12047-HNAE) were acquired from Sino Biological Inc. (Beijing, China). IL-23 (PRP1909) was bought from Abbkine (Wuhan,

(2) Upregulated SKP2 Empowers Epidermal Proliferation Through Downregulation of P27 Kip1Annals of DermatologyMay 17, 2024Lipeng Tang, Bowen Zhang, Guanzhuo Li, Xinmin Qiu, Zixin Dai, Hongying Liu, Ying Zhu, Bing Feng, Zuqing Su, Wenhui Han, et al.ng/ml) were used to stimulate HaCaT cells for inducing hyperproliferation of keratinocytes. IL-17A (12047-HNAE), IL-6 (10395-HNAE) and TNF-α (10602-HNAE) were purchased from Sino Biological Inc. (Beijing, China). SKP2

(3) Punicalagin Alleviates Psoriasis by Inhibiting NF-κB-Mediated IL-1β Transcription and Caspase-1-Regulated IL-1β SecretionFrontiers in pharmacologyJanuary 1, 2022Tang L, Li T, Zhang B, Zhang Z, Sun X, Zhu Y, Feng B, Su Z, Yang L, Li H, et al.States). IMQ cream was obtained from Sichuan Med-Shine Pharmaceutical Co., Ltd. (Sichuan, China). IL-17A (12047-HNAE), TNF-α (10602-HNAE), IL-1β (10139-HNAE) were purchased from Sino Biological Inc. (Beijing, China). Mice

(4) Recombinant Anti-idiotypic Antibodies in Ligand Binding Assays for Antibody Drug DevelopmentMethods in molecular biology (Clifton, N.J.)January 1, 2021Harth S, Frisch C.

(5) Computational Design of Epitope-Specific Functional AntibodiesCell reportsNovember 20, 2018Nimrod G, Fischman S, Austin M, Herman A, Keyes F, Leiderman O, Hargreaves D, Strajbl M, Breed J, Klompus S, et al.

(6) Magnolol Attenuates Concanavalin A-induced Hepatic Fibrosis, Inhibits CD4⁺ T Helper 17 (Th17) Cell Differentiation and Suppresses Hepatic Stellate Cell Activation: Blockade of Smad3/Smad4 SignallingBasic & clinical pharmacology & toxicologyJune 1, 2017Zhang H, Ju B, Zhang X, Zhu Y, Nie Y, Xu Y, Lei Q.

(7) Human S100A7 Induces Mature Interleukin1α Expression by RAGE-p38 MAPK-Calpain1 Pathway in PsoriasisPloS oneJanuary 1, 2017Lei H, Li X, Jing B, Xu H, Wu Y.Cell Signaling Technology. The antibody for human S100A7 (11141-RP02), soluble recombinant human S100A7 (11141-HNAE), IL17A (12047-HNAE), IL-22 (13059-HNAE), IL-33 (10368-HNAE), IL36γ (10124-HNAE) and TNFα (10602-HNAE) were purchased from Sino Biological Inc

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Human IL17 / IL17A Protein

Human IL17 / IL17A Protein from Sino Biological, Inc.

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Sino Biological, Inc.

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Human IL17 / IL17A Protein from Sino Biological, Inc.

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