Human bFGF / FGF2 Protein 10014-HNAE from Sino Biological, Inc.

Product Specs
ItemHuman bFGF / FGF2 Protein
CompanySino Biological, Inc.
Price $178.00Supplier Page View Company Product Page
Catalog Number10014-HNAE
Size100 µg
Conjugate/TagUnconjugated
Purity≥ 95 % as determined by SDS-PAGE
TypeRecombinant protein
Molecular WeightThe recombinant human bFGF consists of 147 amino acids and predicts a molecular mass of 16.5 kDa
SpeciesHuman
Molecule NameFGF2
Source/Expression SystemE. coli
Activity1.iPSC-derived human vascular organoids (Day 7) were cultured with FGF2 (Cat#10014-HNAE), VEGFA (Cat# 11066-HNAH), EGF (Cat#10605-HNAE). Red arrows represent vascular organoids. Image taken at 10x magnification.(Routinely tested) 2.Measured in a cell proliferation assay using Balb/c 3T3 mouse embryonic fibroblasts. The ED50 for this effect is typically 0.01-0.1 ng/mL. 3.Human lung cancer organoids were cultured with FGF2(Cat#10014-HNAE), FGF4(Cat#16043-HNAE), FGF7(Cat#10210-H07E), EGF(Cat#50482-MNCH), FGF10(Cat#10573-HNAE), NOG(Cat#50688-M02H), RSPO1(Cat#11083-HNAS). (Routinely tested). Data provided by D1 Medical Technology. 4.Human lung organoids were cultured with FGF2(Cat#10014-HNAE), FGF4(Cat#16043-HNAE), FGF7(Cat#10210-H07E), EGF(Cat#50482-MNCH), FGF10(Cat#10573-HNAE), NOG(Cat#50688-M02H), RSPO1(Cat#11083-HNAS). (Routinely tested). Data provided by D1 Medical Technology. 5.Human cholangiocarcinomas organoids were cultured with FGF2(Cat#10014-HNAE), HGF(Cat#10463-HNAS), FGF7(Cat#10210-H07E), EGF(Cat#50482-MNCH), FGF10(Cat#10573-HNAE), NOG(Cat#50688-M02H), RSPO1(Cat#11083-HNAS). (Routinely tested). Data provided by D1 Medical Technology. 6.Human liver cancer organoids were cultured with FGF2(Cat#10014-HNAE), HGF(Cat#10463-HNAS), FGF7(Cat#10210-H07E), EGF(Cat#50482-MNCH), FGF10(Cat#10573-HNAE), TGFB1(Cat#10804-HNAC), NOG(Cat#50688-M02H), RSPO1(Cat#11083-HNAS). (Routinely tested). Data provided by D1 Medical Technology. 7.Human kidney cancer organoids were cultured with FGF2(Cat#10014-HNAE), FGF7(Cat#10210-H07E), EGF(Cat#50482-MNCH), FGF10(Cat#10573-HNAE), NOG(Cat#50688-M02H), RSPO1(Cat#11083-HNAS). (Routinely tested). Data provided by D1 Medical Technology
FormatLyophilized from sterile PBS, pH 7.4

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) Physical crowding in 3D niche regulates neural stem cell differentiation via Cx43-mediated gap junction communicationiScienceApril 17, 2026Yuyun Liang, Xiaonan Wang, Chaoyong He, Zhiyan Wu, Jing Yang, Ziyan Chen, Hexu Zhang, Cheng Zhao, Liyang Shiproteins" ,, Type Ⅰ collagen,DB Wunderegen,– EGF,Sino Biological,Cat# 10605 bFGF,Sino Biological,Cat# 10014-HNAE DMEM/F12,Gibco,Cat# C11330500BT L-glutamine,Gibco,Cat# 25038801 Sodium pyruvate,Gibco,Cat# 11360070 NEAA,Gibco,Cat#

(2) A cocktail hydrogel promoting the functional interneurons regeneration of human neural progenitor cells for brain injury therapyJournal of Advanced ResearchMarch 1, 2026Di Zhang, Jun Chen, Huaisong Lin, Min Zhou, Jinfei Hou, Wei Sun, Qi Xing, Wenhao Huang, Yanqi Zhang, Yiping Guo, et al.for 4 days. To induce differentiation into hNPCs, 20 ng mL−1 basic fibroblast growth factors (bFGFs) (10014-HNAE-1, Sino Biological) were added for an additional 4 days. For the identification of hPSCs, protein markers

(3) CD80-Mediated T-Cell Suppression by Cancer Stem-like Cells in Head and Neck Squamous Cell CarcinomaCellsJanuary 30, 2026Mian Xiao, Lin Qiu, Qian Gao, Ruifeng Li, Jing Wang, Yanrui Feng, Xuefen Li, Xiyuan GeBeijing, China, Cat#10605-HNAE), 20 ng/mL human recombinant bFGF (SinoBiological, Beijing, China, Cat#10014-HNAE), 1% B-27 (Thermo Fisher Scientific, Waltham, MA, USA, Cat#17504044) and N2 (Thermo Fisher Scientific,

(4) IGF2BP2 Drives Thyroid Cancer Dedifferentiation Through m6A-Dependent STAT1 mRNA DestabilizationInternational Journal of Biological SciencesJanuary 1, 2026Rui Chen, Yi-xun Li, Wei-lin Lu, Ke-fei Wu, Yu-xin Wang, Zi-wen Wang, Yi-han Li, Hai-yan Yang, Xu Zhang, Liang Shi, et al.USA, 2389253), EGF (SinoBiological, China, 10505-HNAE-100, 20 ng/mL) and bFGF (SinoBiological, China, 10014-HNAE-10, 20 ng/mL). The cells were then seeded in low-adhesion plates (Corning, China, 36421016) and cultured

(5) Free-floating patient-derived organotypic tumor spheroids (PDOTS) from non-small cell lung cancer (NSCLC) tumors: a versatile tool for personalized testing of chemotherapeutic drugsResearch in Pharmaceutical SciencesOctober 20, 2025Lilian Ismail, Komal Zahid, Anna Polyanskaya, Aya Al Othman, Ningfei Shen, Xiaoli Qi, Rushan Sulimanov, Yuri Esakov, Vladimir Makarov, Gleb Filkov, et al.medium for spheroids (DMEM/F12 supplemented with 20 ng/mL of basic fibroblast growth factor (bFGF; 10014-HNAE, SinoBiological, China), 50 ng/mL human epidermal growth factor (EGF; ab55566, Abcam, UK), N2 (PanEco,

(6) Lotus fiber-derived scaffolds for enhanced cultured meat production: Quality and sustainabilityBioactive materialsSeptember 1, 2025Wu Y, Li Y, Yang Q, He C, Tang J, Shi L, Dai J, Zhang C.serum (FBS, Gibco, S-FBS-SA-015), 5 ng/mL basic fibroblast growth factor (bFGF, Sino Biological Inc, 10014-HNAE), 1 % (v/v) non-essential amino acids (Gibco, 11140-050), 0.5 % (v/v) chicken embryo extract (GEMINI,

(7) Sperm-Derived CircRNA-1572 Regulates Embryogenesis and Zygotic Genome Activation by Targeting CCNB2 via Bta-miR-2478-L-2Advanced science (Weinheim, Baden-Wurttemberg, Germany)May 1, 2025Wu Y, Wei Y, Li Y, Dou Y, Yang Y, Liu H, Wang X, Wang Z, Su J, Zhang Y, et al.Hormone Factory No.2), 40 ng mL−1 fibroblast growth factor 2 (FGF‐2, Sino Biological, Beijing, China, 10014‐HNAE), 20 ng mL−1 insulin‐like growth factor 1 (IGF‐1, Sino Biological,10598‐HNAE), 20 ng mL−1 leukemia inhibitory

(8) Programmed death-ligand 1 regulates ameloblastoma growth and recurrenceInt J Oral SciApril 16, 2025Linzhou Zhang, Hao Lin, Jiajie Liang, Xuanhao Liu, Chenxi Zhang, Qiwen Man, Ruifang Li, Yi Zhao, Bing Liu#9094360), 10 ng/mL human FGF10 (PeproTech, #100-26-5), 5 ng/mL human FGF2 (Sino Biological Inc., #10014-HNAE), 1 μmol/L prostaglandin E2 (MCE, #HY-101952), 0.3 μmol/L CHIR 99021 (Sigma, #SML1046), 1 μmol/L forskolin

(9) CPT1A-mediated MFF succinylation promotes stemness maintenance in ovarian cancer stem cellsCommunications biologyFebruary 16, 2025Zhu Y, Chen S, Su H, Meng Y, Zang C, Ning P, Hu L, Shao H.Gibco) and 0.4% BSA (#B2064, Sigma), 20 ng/mL EGF (#10605-HNAE, Sino Biological), 20 ng/mL basic FGF (#10014-HNAE, Sino Biological) and 12 ng/mL LIF (#14890-HNAH, Sino Biological). CSCs medium 2: DMEM/F12 medium (Gibco)

(10) Generation of iPSC-derived human venous endothelial cells for the modeling of vascular malformations and drug discoveryCell stem cellFebruary 6, 2025Pan Z, Yao Q, Kong W, Ma X, Tian L, Zhao Y, Zhu S, Chen S, Sun M, Liu J, et al.

(11) TET3-facilitated differentiation of human umbilical cord mesenchymal stem cells into oligodendrocyte precursor cells for spinal cord injury recoveryJournal of translational medicineDecember 20, 2024Zhang Y, Peng Z, Guo M, Wang Y, Liu J, Liu Y, Li M, Wei T, Li P, Zhao Y, et al.induction medium: DMEM/F12 medium (Corning) supplemented with 2% B27 (17504044, Gibco), 20 ng/ml bFGF (10014-HNAE, Sino Biological), 20 ng/ml EGF (10014-HNAE, Sino Biological), and 10 ng/ml PDGF-AA (100-13A, Peprotech)

(12) STAU1-mediated CNBP mRNA degradation by LINC00665 alters stem cell characteristics in ovarian cancerBiology directJuly 30, 2024Liu X, Chen Y, Li Y, Bai J, Zeng Z, Wang M, Dong Y, Zhou Y.

(13) A LATS2 and ALKBH5 positive feedback loop supports their oncogenic rolesCell reportsApril 23, 2024Cao L, Han R, Zhao Y, Qin X, Li Q, Xiong H, Kong Y, Liu Z, Li Z, Dong F, et al.

(14) Single-cell transcriptomics reveals cell atlas and identifies cycling tumor cells responsible for recurrence in ameloblastomaInternational journal of oral scienceFebruary 29, 2024Xiong G, Xie N, Nie M, Ling R, Yun B, Xie J, Ren L, Huang Y, Wang W, Yi C, et al.Cat#9094360), 10 ng/mL human FGF10 (PeproTech, Cat#100-26-5), 5 ng/mL human FGF2 (Sino Biological Inc, Cat#10014-HNAE), 1 μmol/L prostaglandin E2 (MCE, Cat#HY-101952), 0.3 μmol/L CHIR 99021 (Sigma, Cat#SML1046), 1 μmol/L

(15) NCAPG2 promotes prostate cancer malignancy and stemness via STAT3/c-MYC signalingJournal of translational medicineJanuary 2, 2024Zhang E, Chen Z, Liu W, Lin L, Wu L, Guan J, Wang J, Kong C, Bi J, Zhang M.factor (EGF, 10,605-HNAE, Sino Biological Inc., China), 10 ng/mL basic fibroblast growth factor (bFGF, 10014-HNAE, Sino Biological Inc., China), and 2% B27 supplement (17504044, Thermo Fisher Scientific, USA). Spheres

(16) Three-Dimensional Cell Culture of Epididymal Basal Cells and Organoids: A Novel Tool for ToxicologyCurr ProtocJanuary 1, 2024Dufresne J, Gregory M, Pinel L, Cyr DG.

(17) Rapid conversion of porcine pluripotent stem cells into macrophages with chemically defined conditionsThe Journal of biological chemistryJanuary 1, 2024Wu X, Ni Y, Li W, Yang B, Yang X, Zhu Z, Zhang J, Wu X, Shen Q, Liao Z, et al.with 50 ng/ml VEGFA (Sino Biological, cat. no.11066-HNAH), 50 ng/ml bFGF (Sino Biological, cat. no. 10014-HNAE), 50 ng/ml SCF (Novoprotein, cat. no. C034), and 10 μM SB431542 (MedChemExpress, cat. no. HY-10431).

(18) Mathematical Modeling of Non-Small-Cell Lung Cancer Biology through the Experimental Data on Cell Composition and Growth of Patient-Derived OrganoidsLife (Basel)November 20, 2023Rushan Sulimanov, Konstantin Koshelev, Vladimir Makarov, Alexandre Mezentsev, Mikhail Durymanov, Lilian Ismail, Komal Zahid, Yegor Rumyantsev, Ilya Laskovmedium consisted of DMEM/F12 supplemented with 20 ng mL−1 of basic fibroblast growth factor (bFGF, 10014-HNAE, Sino Biological, Beijing, China), 50 ng mL−1 of human epidermal growth factor (EGF, ab55566, Abcam,

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(20) TRAF7-targeted HOXA5 acts as a tumor suppressor in prostate cancer progression and stemness via transcriptionally activating SPRY2 and regulating MEK/ERK signalingCell death discoveryOctober 16, 2023Ye J, Liu W, Yu X, Wu L, Chen Z, Yu Y, Wang J, Bai S, Zhang M.factor (EGF, 10605-HNAE, Sino Biological Inc., China), 10 ng/mL of basic fibroblast growth factor (bFGF, 10014-HNAE, Sino Biological Inc., China), and 2% B27 supplement (17504044, Thermo Fisher Scientific, USA). The

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Human bFGF / FGF2 Protein

Human bFGF / FGF2 Protein from Sino Biological, Inc.

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Sino Biological, Inc.

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Human bFGF / FGF2 Protein from Sino Biological, Inc.

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