Mouse CTLA4 / CD152 Protein (ECD,His Tag) 50503-M08H from Sino Biological, Inc.

Product Specs
ItemMouse CTLA4 / CD152 Protein (ECD,His Tag)
CompanySino Biological, Inc.
Price $128.00Supplier Page View Company Product Page
Catalog Number50503-M08H
Conjugate/TagC-His
Purity≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC
TypeRecombinant protein
Molecular WeightThe recombinant mouse CTLA4 consists of 138 amino acids and has a predicted molecular mass of 15.46 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of mouse CTLA4 is approximately 25-30 kDa due to glycosylation
SpeciesMouse
Molecule NameCTLA4
Source/Expression SystemHEK293 Cells
NCBI Full Gene Namecytotoxic T-lymphocyte-associated protein 4
NCBI Gene AliasesCd152, Ctla-4, Ly-56
Activity1.Immobilized Recombinant Mouse CD80 / B7-1 Protein (Fc Tag) (Cat:50446-M02H) at 2µg/mL (100µL/well) can bind Recombinant Mouse CTLA4 / CD152 Protein (ECD,His Tag) (Cat:50503-M08H), the EC50 is 1.0-3.0 ng/mL(QC tested). 2.Measured by its ability to inhibit IL-2 secretion by stimulated Jurkat human acute T cell leukemia cells. The ED50 for this effect is 0.1-0.5µg/mL when stimulated with 1 µg/mL Recombinant Human B7-1/CD80(Routinely tested). 3.Immobilized Recombinant Mouse CD86 / B7-2 Protein (Fc Tag) (Cat: 50068-M02H) at 5 µg/mL (100 µL/well) can bind Recombinant Mouse CTLA4 / CD152 Protein (ECD,His Tag) (Cat: 50503-M08H), the EC50 is 4.0 ng/mL (Routinely tested)
FormatLyophilized from sterile PBS, pH 7.4
Size100 µg

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) Antitumor effect of plant-produced anti-CTLA-4 monoclonal antibody in a murine model of colon cancerFrontiers in Plant ScienceAugust 29, 2023Christine Joy I. Bulaon, Narach Khorattanakulchai, Kaewta Rattanapisit, Hongyan Sun, Nuttapat Pisuttinusart, Richard Strasser, Shiho Tanaka, Patrick Soon-Shiong, Waranyoo PhoolcharoenCTLA-4 protein (huCTLA-4) (11159-H08H, SinoBiological, China) and mouse CTLA-4 protein (muCTLA-4) (50503-M08H, SinoBiological, China) were used to verify the binding activity of plant-produced anti-CTLA-4 2C8 mAb

(2) Activity of murine surrogate antibodies for durvalumab and tremelimumab lacking effector function and the ability to deplete regulatory T cells in mouse models of cancermAbsJanuary 1, 2021Schofield DJ, Percival-Alwyn J, Rytelewski M, Hood J, Rothstein R, Wetzel L, McGlinchey K, Adjei G, Watkins A, Machiesky L, et al.PD-L1 (catalog no. 10084-H08H), human CTLA-4 (catalog no. 11159-H08H), and mouse CTLA-4 (catalog no. 50503-M08H) were purchased from Sino Biological. For human anti–PD-L1 and mouse anti–CTLA-4 binding assays, mouse

(3) Self-Assembled Multivalent Aptamer Nanoparticles with Potential CAR-like Characteristics Could Activate T Cells and Inhibit Melanoma GrowthMolecular therapy oncolyticsJune 26, 2020Bai C, Gao S, Hu S, Liu X, Li H, Dong J, Huang A, Zhu L, Zhou P, Li S, et al.for 10 min. Target recombinant proteins (mouse CD28, Abcam, ab207143; mouse CTLA-4, Sino Biological, 50503-M08H; mouse PD1, Sino Biological, 50124-M08H; mouse TIM3, Sino Biological, 51152-M08H; mouse TIGIT, Sino Biological

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Mouse CTLA4 / CD152 Protein (ECD,His Tag)

Mouse CTLA4 / CD152 Protein (ECD,His Tag) from Sino Biological, Inc.

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Sino Biological, Inc.

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Mouse CTLA4 / CD152 Protein (ECD,His Tag) from Sino Biological, Inc.

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