Human TNFRSF4 / OX40 / CD134 Protein (His Tag) 10481-H08H from Sino Biological, Inc.

Product Specs
ItemHuman TNFRSF4 / OX40 / CD134 Protein (His Tag)
CompanySino Biological, Inc.
Price $298.00Supplier Page View Company Product Page
Catalog Number10481-H08H
Size100 µg
Conjugate/TagC-His
Purity≥ 90 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC
Activity1.Measured by its binding ability in a functional ELISA. Immobilized TNFRSF4-His (Cat: 10481-H08H) at 2 µg/ml (100 µl/well) can bind human TNFSF4-mFc (Cat: 13127-H04H), the EC50 of human TNFSF4-mFc is 60-240 ng/mL. 2.Loaded Recombinant Human OX40 Ligand/TNFSF4 Protein, hFc Tag (Cat. No. 13127-H01H) on ProA Biosensor, can bind Recombinant Human OX40/TNFRSF4 Protein, His Tag (Cat. No. 10481-H08H) with an affinity constant of 0.909 µM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested). 3.Loaded Vonlerolizumab on ProA Biosensor, can bind Recombinant Human OX40/TNFRSF4 Protein, His Tag (Cat. No. 10481-H08H) with an affinity constant of 1.33 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested). 4.Loaded Recombinant Human TNFRSF4 / OX40 / CD134 Protein (His Tag) (Cat. No. 10481-H08H) on Ni-NTA Biosensor, can bind Recombinant Human OX-40L / TNFSF4 / CD252 Protein (ECD,Fc Tag) (Cat. No. 13127-H04H) with an affinity constant of 10.31 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested)
FormatLyophilized from sterile PBS, pH 7.4
TypeRecombinant protein
Molecular WeightThe recombinant human TNFRSF4 consists of 199 amino acids after removal of the signal peptide and has a predicted molecular mass of 21.7 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh TNFRSF4 is approximately 40-45 kDa due to glycosylation
SpeciesHuman
Molecule NameTNFRSF4
Source/Expression SystemHEK293 Cells
NCBI Full Gene NameTNF receptor superfamily member 4
NCBI Gene AliasesACT35, CD134, IMD16, OX40, TXGP1L

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) HFB301001, an OX40-based immunotherapy, drives Treg clearance and CTL activation through optimized OX40 receptor clusteringJournal for ImmunoTherapy of CancerMarch 30, 2026Jiliang Zhao, Dongping Zhang, Yun-Yueh Lu, Ruina Jin, Fan Li, Zhaoyuan Zhang, Wentao Ni, Nanxin Gong, Yi Wang, Zhongqian Yin, et al.Hydrogen/deuterium exchange mass spectrometry (HDX-MS) was employed to map the epitope on the His-tagged human OX40 extracellular domain (Cat: 10481-H08H, Sino Biological, China), which is recognized by monoclonal antibody HFB301001. Purified hOX40 (2 mg/mL),

(2) Pioneer: a synthetic human antibody phage display library for rapid therapeutic lead generationmAbsDecember 1, 2025Putyrski M, Hentrich C, Cavada M, Wich M, Kellmann SJ, Hanselka S, Eick-Werner M, Hanuschka H, Preis W, Werkmeister C, et al.

(3) Establishment of novel anti-TIM-3 antibodies interfering with its binding to ligandsHeliyonMarch 18, 2024Zhuohong Yan, Teng Ma, Xiaojue Wang, Ling Yi, Panjian Wei, Hongtao Zhang, Jinghui WangChina; 10390-H08H), CD137-His (hCD137; Sino Biological, 10041-H08H), OX40-His (hOX40; Sino Biological, 10481-H08H), PD-L1-His (hPD-L1; Sino Biological, 10084-H08H), mouse TIM-3-His (mTIM-3; Sino Biological, 51152-M08H),

(4) Novel anti-4-1BB×PD-L1 bispecific antibody augments anti-tumor immunity through tumor-directed T-cell activation and checkpoint blockadeJournal for immunotherapy of cancerJuly 1, 2021Jeong S, Park E, Kim HD, Sung E, Kim H, Jeon J, Kim Y, Jung UJ, Son YG, Hong Y, et al.10041-H02H, monkey 4-1BB: 90847-K02H, human B7-H3: 11188-H08H, human B7-H4: 10738-H08H, human OX40: 10481-H08H, human GITR: 10643-H08H). Each well of the Nunc Maxisorp plate was coated with 0.5 µg/mL of proteins

(5) Pharmacokinetic Engineering of OX40-Blocking Anticalin Proteins Using Monomeric Plasma Half-Life Extension DomainsFrontiers in pharmacologyJanuary 1, 2021Siegemund M, Oak P, Hansbauer EM, Allersdorfer A, Utschick K, Winter A, Grasmüller C, Galler G, Mayer JP, Weiche B, et al.C-terminus or was purchased from R&D Systems (#3388-OX). Human OX40-His was from Sino Biological (#10481-H08H). SULFO-TAG Streptavidin (#R32AD) and other ECLA specific equipment was from MSD. Anti-His-Tag Antibody

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Human TNFRSF4 / OX40 / CD134 Protein (His Tag)

Human TNFRSF4 / OX40 / CD134 Protein (His Tag) from Sino Biological, Inc.

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Sino Biological, Inc.

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Human TNFRSF4 / OX40 / CD134 Protein (His Tag) from Sino Biological, Inc.

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