Human IL-1 beta / IL1B (E6K) Protein (pro form, His Tag) 10139-H07E from Sino Biological, Inc.

Product Specs
ItemHuman IL-1 beta / IL1B (E6K) Protein (pro form, His Tag)
CompanySino Biological, Inc.
Price $448.00Supplier Page View Company Product Page
Catalog Number10139-H07E
Size100 µg
Conjugate/TagN-His
Purity≥ 90 % as determined by SDS-PAGE
TypeRecombinant protein
Molecular WeightThe recombinant pro form of human IL1β consisting of 280 amino acids and has a calculated molecular mass of 32.3 kDa. It migrates as an approximately 34 kDa band in SDS-PAGE under reducing conditions
SpeciesHuman
Molecule NameIL1B
Source/Expression SystemE. coli
NCBI Full Gene Nameinterleukin 1 beta
NCBI Gene AliasesIL-1, IL1-BETA, IL1F2, IL1beta
Activity1. Measured by its binding ability in a functional ELISA. 2. Immobilized human IL1B at 10 µg/mL (100 µl/well) can bind human IL1R1. The EC50 of human IL1R1 is 0.198 µg/mL
FormatLyophilized from sterile PBS, pH 7.4

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) Lactic acid drives NLRP3 inflammasome activation and caspase-1–like cytokine cleavage via intracellular acidificationCell Death & DiseaseApril 3, 2026Hsin-An Lin, Hsin-Chung Lin, Ming-Hang Tsai, Yu-Jen Chen, Bo-Ying Bao, Kuen-Jou Tsai, Chieh-Tien Shih, Jau-Song Yu, Kun-Yi Chien, Kuo-Yang Huang, et al.version 2.6. Sample preparation and in-gel collection Recombinant pro-IL-1β protein (Sino Biological, #10139-H07E) was incubated with either 30 mM lactic acid (Sigma, #L6661-100ML) or 0.02 U/μL of active recombinant

(2) Loss of Fsr quorum sensing promotes biofilm formation and worsens outcomes in enterococcal infective endocarditisNature CommunicationsJanuary 14, 2026Haris Antypas, Verena Schmidtchen, Willy Isao Staiger, L I Yanhong, Rachel Jing Wen Tan, Kenneth Kok Fei NG, Cheryl Jia Yi Neo, Shalome Meera Radhesh, Frederick Reinhart Tanoto, Ronni Anderson Gonçalves da Silva, et al.mutants were diluted 1:10 in 200 µl fresh BHI supplemented with human pro-IL-1β (100 ng/mL; Cat. Nr. 10139-H07E, Sino Biological) and incubated for 2, 4, 6 and 24 h, or with rat pro-IL-1β (10 ng/ml, Cat. Nr. 80023-R07E,

(3) CD44 is a macrophage receptor for TcdB from Clostridioides difficile that via its lysine-158 succinylation contributes to inflammationGut microbesDecember 1, 2025Chen Z, Zhang W, Wang D, Luo R, Yao Y, Tao X, Li L, Pan Q, Sun X.Molecular Devices, Silicon Valley, CA, USA). Human IL-1β and IL-6 were purchased from SinoBiological (Cat# 10139-H07E; Cat# 10395-HNAE). To simulate the effects of macrophages located within the intestinal epithelium on

(4) Fsr quorum sensing system restricts biofilm growth and activates inflammation in enterococcal infective endocarditisbioRxivFebruary 7, 2025Haris Antypas, Verena Schmidtchen, Willy Isao Staiger, Yanhong Li, Rachel Jing Wen Tan, Kenneth Kok Fei Ng, Cheryl Jia Yi Neo, Shalome Meera Radhesh, Frederick Reinhart Tanoto, Ronni Anderson Gonçalves da Silva, et al.mutants were diluted 1:10 in 200 fresh BHI supplemented with human pro-IL-1beta (100 ng/mL; Cat. Nr. 10139-H07E, Sino Biological) and incubated for 2, 4, 6 and 24 h at 37°C, static conditions. Media was additionally

(5) Caspase-3 targets pro-interleukin-1β (IL-1β) to restrict inflammationFEBS lettersJune 1, 2024Kim SS, Seo SR.

(6) Matrix Metalloproteinase-9-Dependent Release of IL-1β by Human EosinophilsMediators of inflammationJanuary 1, 2019Esnault S, Kelly EA, Johnson SH, DeLain LP, Haedt MJ, Noll AL, Sandbo N, Jarjour NN.

(7) Deep Coverage Tissue and Cellular Proteomics Revealed IL-1β Can Independently Induce the Secretion of TNF-Associated Proteins from Human SynoviocytesJournal of immunology (Baltimore, Md. : 1950)January 15, 2018Tang S, Deng S, Guo J, Chen X, Zhang W, Cui Y, Luo Y, Yan Z, He QY, Shen S, et al.

(8) Cathepsin S is the major activator of the psoriasis-associated proinflammatory cytokine IL-36γProceedings of the National Academy of Sciences of the United States of AmericaMarch 28, 2017Ainscough JS, Macleod T, McGonagle D, Brakefield R, Baron JM, Alase A, Wittmann M, Stacey M.

(9) Acid-dependent Interleukin-1 (IL-1) Cleavage Limits Available Pro-IL-1β for Caspase-1 CleavageThe Journal of biological chemistryOctober 16, 2015Edye ME, Brough D, Allan SM.

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Human IL-1 beta / IL1B (E6K) Protein (pro form, His Tag)

Human IL-1 beta / IL1B (E6K) Protein (pro form, His Tag) from Sino Biological, Inc.

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Sino Biological, Inc.

Citations (9)

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Human IL-1 beta / IL1B (E6K) Protein (pro form, His Tag) from Sino Biological, Inc.

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