Human HER3 / ErbB3 Protein (ECD, Fc Tag) 10201-H02H from Sino Biological, Inc.

Product Specs
ItemHuman HER3 / ErbB3 Protein (ECD, Fc Tag)
CompanySino Biological, Inc.
Price $298.00Supplier Page View Company Product Page
Catalog Number10201-H02H
Activity1.Immobilized HER3/ERBB3 Protein, Human, Recombinant (ECD, hFc Tag)(Cat:10201-H02H) at 2 µg/mL (100 µL/well) can bind NRG1 Beta 1 Protein, Human, Recombinant,Biotinylated(EGF Domain, Avi&Fc Tag)(Cat:11609-H01H-B), the EC50 is 220-1200 ng/mL (QC tested). 2.Immobilized Recombinant Human HER3 / ErbB3 Protein (ECD, Fc Tag) (Cat: 10201-H02H) at 2 µg/mL (100 µL/well) can bind Anti-HER3 (Research Grade Patritumab Biosimilar), the EC50 is 2-6 ng/mL (Rountinely tested). 3.Immobilized Recombinant Human HER3 / ErbB3 Protein (ECD, Fc Tag) (Cat: 10201-H02H) at 2 µg/mL (100 µL/well) can bind Recombinant Human NRG1-beta 1 Protein (ECD, Fc Tag) (Cat: 11609-H04H), the EC50 is 4.0 ng/mL (Routinely tested)
FormatLyophilized from sterile PBS, pH 7.4
NCBI Gene AliasesErbB-3, FERLK, HER3, LCCS2, MDA-BF-1, VSCN1, c-erbB-3, c-erbB3, erbB3-S, p180-ErbB3, p45-sErbB3, p85-sErbB3
NCBI Full Gene Nameerb-b2 receptor tyrosine kinase 3
Source/Expression SystemHEK293 Cells
Molecule NameERBB3
SpeciesHuman
Molecular WeightThe mature recombinant human ErbB3/Fc chimera is a disulfide-linked homodimeric protein after the removal of signal peptide. The monomer consists of 862 amino acids and has a calculated molecular mass of 95.4 kDa. As a result of glycosylation, the recombinant monomer migrates as an approximately 130-140 kDa protein in SDS-PAGE under reducing conditions
TypeRecombinant protein
Purity≥ 90 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC
Conjugate/TagC-human IgG1-Fc
Size100 µg

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) A novel bispecific antibody drug conjugate targeting HER2 and HER3 with potent therapeutic efficacy against breast cancerActa pharmacologica SinicaAugust 1, 2024Zong HF, Li X, Han L, Wang L, Liu JJ, Yue YL, Chen J, Ke Y, Jiang H, Xie YQ, et al.

(2) A novel HER2-targeting antibody 5G9 identified by large-scale trastuzumab-based screening exhibits potent synergistic antitumor activityEBioMedicineOctober 1, 2020Ding X, Gu W, Zhong Y, Hao X, Liu J, Xia S, Luo L, Chen M, Zhang C.Incorporated. The recombinant proteins huEGFR (Cat# 10001-H02H), huHER2 (Cat# 10004-H02H), huHER3 (Cat# 10201-H02H), huHER4 (Cat# 10363-H02H), rhesus HER2 (Cat# 90020-K02H) and mouse HER2 (Cat# 50714-M02H) were purchased

(3) Molecular Design of HER3-Targeting Affibody Molecules: Influence of Chelator and Presence of HEHEHE-Tag on Biodistribution of ⁶⁸Ga-Labeled TracersInternational journal of molecular sciencesMarch 2, 2019Dahlsson Leitao C, Rinne SS, Mitran B, Vorobyeva A, Andersson KG, Tolmachev V, Ståhl S, Löfblom J, Orlova A.

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Human HER3 / ErbB3 Protein (ECD, Fc Tag)

Human HER3 / ErbB3 Protein (ECD, Fc Tag) from Sino Biological, Inc.

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Sino Biological, Inc.

Citations (3)

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Human HER3 / ErbB3 Protein (ECD, Fc Tag) from Sino Biological, Inc.

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