Human B7-H3 / CD276 Protein (ECD, Fc Tag) 11188-H02H from Sino Biological, Inc.

Product Specs
ItemHuman B7-H3 / CD276 Protein (ECD, Fc Tag)
CompanySino Biological, Inc.
Price $298.00Supplier Page View Company Product Page
Catalog Number11188-H02H
Size100 µg
Conjugate/TagC-human IgG1-Fc
Purity≥ 95 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC
FormatLyophilized from sterile PBS, pH 7.4
ActivityImmobilized Recombinant Human B7-H3 / CD276 Protein (ECD, Fc Tag) (Cat: 11188-H02H) at 2 µg/mL (100 µL/well) can bind Anti-B7-H3 Antibody, IgG1 Kappa, the EC50 is 6.5-20 ng/mL
TypeRecombinant protein
Molecular WeightThe recombinant human CD276 consists 671 amino acids and predicts a molecular mass of 73.3 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of human CD276 is approximately 109.5 kDa due to glycosylation
SpeciesHuman
Molecule NameCD276
Source/Expression SystemHEK293 Cells
NCBI Full Gene NameCD276 molecule
NCBI Gene Aliases4Ig-B7-H3, B7-H3, B7H3, B7RP-2

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) TSH Ligand-Based CAR-T Cell Effectively Eradicates TSHR-Positive Thyroid Cancer with Favorable Safety ProfileAdvanced science (Weinheim, Baden-Wurttemberg, Germany)December 1, 2025Wang F, Zuo H, Liu L, Wang S, Zhao H, Liu Z, Wang G, Liu Z, Zheng J, Xu C, et al.Expression of B7‐H3‐CAR and CD19‐CAR was detected using B7‐H3‐Fc chimera protein (Sino Biological, 11188‐H02H), followed by the Alexa Fluor 647 Goat anti‐human IgG antibody and the anti‐idiotype mAb (clone 233‐4A),[

(2) Preclinical assessment of the efficacy of B7-H3 CAR-T in renal cell carcinomaMolecular immunologyDecember 1, 2024Li H, Wang F, Zhao H, Cao J, Wang S, Li H, Savoldo B, Rao E, Dotti G, Du H.Expression of B7-H3-CAR and CD19-CAR was detected using B7-H3-Fc Chimera Protein (Sino Biological, 11188-H02H) and the anti-idiotype mAbs 233–4A respectively (Sino Biological, 11880-H02H) and then followed by Alexa

(3) B7-H3 specific CAR-T cells exhibit potent activity against prostate cancerCell Death DiscoveryMay 6, 2023Shibao Li, Miaomiao Zhang, Meng Wang, Haiting Wang, Han Wu, Lijun Mao, Meng Zhang, Huizhong Li, Junnian Zheng, Ping Ma, et al.CAR expression, control T cells or CAR-T cells were incubated with the B7-H3 protein (SinoBiological, 11188-H02H) and then stained with IgG-Fc, followed by anti-CD3 antibody. The proliferation of T cells was evaluated

(4) Effective killing of cells expressing CD276 (B7-H3) by a bispecific T cell engager based on a new fully human antibodyTranslational oncologyDecember 1, 2021Liu X, Zhelev D, Adams C, Chen C, Mellors JW, Dimitrov DS.

(5) B7-H3 promotes colorectal cancer angiogenesis through activating the NF-κB pathway to induce VEGFA expressionCell death & diseaseJanuary 23, 2020Wang R, Ma Y, Zhan S, Zhang G, Cao L, Zhang X, Shi T, Chen W.treated with or without 50 ng/ml recombinant human B7-H3 (rB7-H3, Sino Biological, Beijing, China, #11188-H02H) for 24 h were collected. Conditioned medium CRC cells (1 × 106) were cultured in 6-well plates overnight,

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Human B7-H3 / CD276 Protein (ECD, Fc Tag)

Human B7-H3 / CD276 Protein (ECD, Fc Tag) from Sino Biological, Inc.

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Sino Biological, Inc.

Citations (5)

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Human B7-H3 / CD276 Protein (ECD, Fc Tag) from Sino Biological, Inc.

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