Mouse CD86 / B7-2 Protein (His Tag) 50068-M08H from Sino Biological, Inc.

Product Specs
ItemMouse CD86 / B7-2 Protein (His Tag)
CompanySino Biological, Inc.
Price $178.00Supplier Page View Company Product Page
Catalog Number50068-M08H
Conjugate/TagC-His
Purity≥ 92 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC
TypeRecombinant protein
Molecular WeightThe recombinant mouse CD86 consists of 233 amino acids after removal of the signal peptide and has a predicted molecular mass of 26.8 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rm CD86 is approximately 40-55 kDa due to glycosylation
SpeciesMouse
Molecule NameCD86
Source/Expression SystemHEK293 Cells
NCBI Full Gene NameCD86 antigen
NCBI Gene AliasesB7, B7-2, B7.2, B70, CLS1, Cd28l2, ETC-1, Ly-58, Ly58, MB7, MB7-2, TS/A-2
Activity1.Measured by its binding ability in a functional ELISA. Immobilized mouse CD86 at 20 µg/ml (100 µl/well) can bind mouse CD28 with a linear range of 6.4-800 ng/ml. 2.Loaded Recombinant Mouse CD28 Protein, hFc Tag (Cat. No. 50103-M02H) on proA Biosensor, can bind Recombinant Mouse B7-2/CD86 Protein, His Tag (Cat. No. 50068-M08H) with an affinity constant of 7.750 µM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested)
FormatLyophilized from sterile PBS, pH 7.4
Size100 µg

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) PD-1 and BTLA regulate T cell signaling differentially and only partially through SHP1 and SHP2The Journal of cell biologyJune 1, 2020Xu X, Hou B, Fulzele A, Masubuchi T, Zhao Y, Wu Z, Hu Y, Jiang Y, Ma Y, Wang H, et al.pMHC-I-His, 2 nM mouse ICAM-His (Sino Biological; #50440-M08H), 3 nM mouse CD86-His (Sino Biological; #50068-M08H), and either 8 nM mouse PD-L1–His (Sino Biological; #50010-M08H) or 8 nM mouse HVEM-His (BioLegend;

(2) A functional antibody cross-reactive to both human and murine cytotoxic T-lymphocyte-associated protein 4 via binding to an N-glycosylation epitopemAbsJanuary 1, 2020Li D, Li J, Chu H, Wang Z.mCD80-His tag (Sino Biological, Cat: 50446-M08H) or 5 μg/ml of mCD86-His tag (Sino Biological, Cat: 50068-M08H), and then added to the plates and incubated at room temperature for 1 h. After washing, biotinylated

(3) PD-L1:CD80 Cis-Heterodimer Triggers the Co-stimulatory Receptor CD28 While Repressing the Inhibitory PD-1 and CTLA-4 PathwaysImmunityDecember 17, 2019Zhao Y, Lee CK, Lin CH, Gassen RB, Xu X, Huang Z, Xiao C, Bonorino C, Lu LF, Bui JD, et al.# 50804-M08H Mouse CD80-His,Sino Biological,Cat # 50446-M08H Mouse CD86-His,Sino Biological,Cat # 50068-M08H Mouse ICAM-His,Sino Biological,Cat # 50440-M08H SIINFEKL peptide,Anaspec,Cat# AS-60193–1 Mouse IL-2,Thermo Fisher Scientific

(4) Antigen-Presenting Cell-Intrinsic PD-1 Neutralizes PD-L1 in cis to Attenuate PD-1 Signaling in T CellsCell reportsJuly 10, 2018Zhao Y, Harrison DL, Song Y, Ji J, Huang J, Hui E.50124-m08h Mouse PD-L1EX-His,Sino Biological,Cat # 50010-m08h Mouse B7.2EX-His,Sino Biological,Cat # 50068-m08h Mouse ICAMEX-His,Sino Biological,Cat # 50440-m08h SIINFEKL peptide,Anaspec,Cat # AS-60193-1 Live/Dead

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Mouse CD86 / B7-2 Protein (His Tag)

Mouse CD86 / B7-2 Protein (His Tag) from Sino Biological, Inc.

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Sino Biological, Inc.

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Mouse CD86 / B7-2 Protein (His Tag) from Sino Biological, Inc.

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