Mouse Interleukin-2 / IL-2 Protein 51061-MNAE from Sino Biological, Inc.

Product Specs
ItemMouse Interleukin-2 / IL-2 Protein
CompanySino Biological, Inc.
Price $108.00Supplier Page View Company Product Page
Catalog Number51061-MNAE
Activity1. Measured by its ability to bind recombinant human IL2Ra-Fc (Cat:10165-H02H) in a functional ELISA. 2. Measured in a cell proliferation assay using CTLL2. The ED50 for this effect is typically 6-30 ng/mL
FormatLyophilized from sterile PBS, 2mM DTT, pH 7.4
Size20 µg
Source/Expression SystemE. coli
Molecule NameIL2
SpeciesMouse
Molecular WeightThe recombinant mouse IL2 consists of 150 amino acids and has a calculated molecular mass of 17.4KDa. It migrates as an approximately 19 kDa in SDS-PAGE under reducing conditions
TypeRecombinant protein
Purity> 92 % as determined by SDS-PAGE
Conjugate/TagUnconjugated

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) A distinct TCR+CD19+ population in the peritoneal cavity: B1a cells as precursors of extrathymic T cellsiScienceApril 17, 2026Su-Min Yee, Jeong-Eun Seon, Jae-Eun Seo, Hae-Jin Seo, Ja-Hun Seo, Seo-Hee Moon, Hyun-Su Koo, Ha-Rim Choi, Su-Man Kim, Hyung-Sik KangDNase I,Merck,Cat#11284932001 antibiotic-antimycotic,GIBCO,Cat#15240-062 HEPES,GIBCO,Cat#15630-080 β-mercaptoethanol,GIBCO,Cat#21985023 α-MEM medium,GIBCO,Cat#12561056 Recombinant Mouse IL-2 Protein,Sino Biological Inc.,Cat#51061-MNAE Recombinant Mouse IL-4 Protein,Sino Biological Inc.,Cat#51084-MNAE Recombinant Mouse IL-7 Protein,Sino Biological Inc

(2) Cancer Immunomodulatory Effect of Bidens pilosa L. in Mice: Suppression of Tumor-Associated Macrophages and Regulatory T CellsCellsJanuary 10, 2026Meihua Zhu, Jiayan Xiong, Ruyi Zhang, Xingyan Yang, Weiqing Sun, Ziyi Yang, Yuhan Chai, Yang Tao, Yu-Qiang Zhao, Baomin Fan, et al.anti-IFN-γ antibody (5 μg/mL, eBioscience, Cat. 16-7311-85), IL-2 (100 U/mL, Sino Biological Inc., Cat. 51061-MNAE, Beijing, China), TGF-β (4 ng/mL, Sino Biological Inc., Cat. 51061-MNAE), and rapamycin (100 ng/mL,

(3) LZTR1 regulates epithelial MHC-I expression via NF-κB1 to modulate CD8+ T cells activationCell DiscovOctober 29, 2025Rundong Jiang, Zhiqin Fang, Yutong Wang, Bo Huang, Junkun Liu, Lam C. Tsoi, Rachael Bogle, Zongbo Zhang, Yehong Kuang, Xin Li, et al.Dynabeads™ Mouse T-Activator CD3/CD28 Kit (cat. 11452D, Thermo Fisher) combined with 20 ng/mL IL-2 (cat. 51061-MNAE, Sino Biological) for 3 days. The activation of T cell was detected by FCM with CD44 and CD62L expression. T cell

(4) Chimeric antigen receptor-engineered cytolytic Tregs reverse pulmonary fibrosis and remodel the fibrotic niche without CRSJCI InsightAugust 8, 2025Yun-Han Jiang, Meng Zhou, Meng-Di Cheng, Sai Chen, Ying-Qiang Guothe FAP1 CAR on RetroNectin (Takara, T100B) 6-well plates coated with 100 U/mL IL-2 (Sino Biological, 51061-MNAE). The transduced murine lymphocytes were expanded for 24 hours in the presence of 350 U/mL IL-2. The

(5) TIGIT deficiency promotes autoreactive CD4+ T-cell responses through a metabolic‒epigenetic mechanism in autoimmune myositisNat CommunMay 15, 2025Yimei Lai, Shuang Wang, Tingting Ren, Jia Shi, Yichao Qian, Shuyi Wang, Mianjing Zhou, Ryu Watanabe, Mengyuan Li, Xinyuan Ruan, et al.Cat# 504102), IL-12 (20 ng/ml, PeproTech, Cat# 210-12-2), and IL-2 (20 ng/ml, Sino Biological, Cat# 51061-MNAE). Th2 cells: anti-IFNγ antibody (Clone# R4-6A2, 5 μg/ml, BioLegend, Cat# 505702), IL-4 (20 ng/ml, Sino Biological

(6) Pseudomonas aeruginosa enhances anti-PD-1 efficacy in colorectal cancer by activating cytotoxic CD8+ T cellsFrontiers in ImmunologyMarch 21, 2025Lu Chen, Guangcong Ruan, Xuefei Zhao, Ailin Yi, Zhifeng Xiao, Yuting Tian, Yi Cheng, Dongfeng Chen, Yanling WeieBioscience) antibody-coated culture flasks with RPMI-1640 medium containing 30 U/mL recombinant mouse IL-2 (51061-MNAE, Sino Biological). T cell differentiation was induced for 48 hours in settings containing different

(7) MerTK(+) macrophages promote melanoma progression and immunotherapy resistance through AhR-ALKAL1 activationScience advancesOctober 4, 2024Wu N, Li J, Li L, Yang L, Dong L, Shen C, Sha S, Fu Y, Dong E, Zheng F, et al.

(8) CD226 maintains regulatory T cell phenotype stability and metabolism by the mTOR/Myc pathway under inflammatory conditionsCell reportsOctober 31, 2023Ma J, Hu W, Liu Y, Duan C, Zhang D, Wang Y, Cheng K, Yang L, Wu S, Jin B, et al.

(9) Lymph node fibroblastic reticular cells preserve a tolerogenic niche in allograft transplantation through laminin α4The Journal of clinical investigationJuly 1, 2022Li L, Shirkey MW, Zhang T, Piao W, Li X, Zhao J, Mei Z, Guo Y, Saxena V, Kensiski A, et al.grade, product number 1642802) and BSA (product number A8531) were from Sigma-Aldrich. IL-2 (catalog 51061-MNAE) and TGF-β (catalog 10804-HNAC) were from Sino Biological US. Mouse CCL21 (catalog RND-AF457) was from

(10) Eosinophils regulate intra-adipose axonal plasticityProceedings of the National Academy of Sciences of the United States of AmericaJanuary 18, 2022Meng X, Qian X, Ding X, Wang W, Yin X, Zhuang G, Zeng W.Gr-1, TER119, and NK1.1. The cells were expanded for three days with the addition of 10 ng/mL IL-2 (51061-MNAE-20; Sino Biological) and 10 ng/mL IL-7 (50217-MNAE-20; Sino Biological) before further stimulation.

(11) Extracellular Vesicles from Akkermansia muciniphila Elicit Antitumor Immunity Against Prostate Cancer via Modulation of CD8⁺ T Cells and MacrophagesInternational journal of nanomedicineJanuary 1, 2021Luo ZW, Xia K, Liu YW, Liu JH, Rao SS, Hu XK, Chen CY, Xu R, Wang ZX, Xie H.1% PS in the presence of 1 mM pyruvic acid sodium, 0.05 mM βmercaptoethanol, and 10 ng/mL of IL-2 (51061-MNAE; Sino Biological, Beijing, China) for two days. Anti-mouse CD3ε/CD28 antibodies (2 μg/mL; 100339 and

(12) Utilizing VEGF165b mutant as an effective immunization adjunct to augment antitumor immune responseVaccineApril 3, 2019Zhang H, Jia E, Xia W, Lv T, Lu C, Xu Z, Zhu W.

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Mouse Interleukin-2 / IL-2 Protein

Mouse Interleukin-2 / IL-2 Protein from Sino Biological, Inc.

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Sino Biological, Inc.

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Mouse Interleukin-2 / IL-2 Protein from Sino Biological, Inc.

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