Human IL18RAP / IL1R7 Protein (His Tag) 10176-H08H from Sino Biological, Inc.

Product Specs
ItemHuman IL18RAP / IL1R7 Protein (His Tag)
CompanySino Biological, Inc.
Price $348.00Supplier Page View Company Product Page
Catalog Number10176-H08H
FormatLyophilized from sterile PBS, pH 7.4
ActivityLoaded Recombinant Human IL-18R beta / IL-18RAP Protein, His Tag (Cat. No. 10176-H08H) on His1K Biosensor, can bind Recombinant Human IL-18Rα Protein, hFc Tag (Cat. No. 11102-H02H) (Premixed with Human IL-18 Protein, Tag Free, Cat. No. 10119-HNCE) with an affinity constant of 42.9 nM as determined in BLI assay (Sartorius Octet RED384) (QC tested)
NCBI Gene AliasesACPL, CD218b, CDw218b, IL-18R-beta, IL-18RAcP, IL-18Rbeta, IL-1R-7, IL-1R7, IL-1RAcPL, IL18RB
NCBI Full Gene Nameinterleukin 18 receptor accessory protein
Source/Expression SystemHEK293 Cells
Molecule NameIL18RAP
SpeciesHuman
Molecular WeightThe recombinant human IL18RAP consists of 349 amino acids and has a calculated molecular mass of 40 kDa. As a result of glycosylation, the apparent molecular mass of rh IL18RAP is approximately 50-55 kDa in reduced SDS-PAGE
TypeRecombinant protein
Purity≥ 97 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC
Conjugate/TagC-His
Size100 µg

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(1) Structure-Guided Stapling of Dimeric Conformations and Linker Engineering Enhance Thermostability and Fine-Tune Activity of Bispecific VHH Cytokine AgonistsAntibodies (Basel)September 1, 2025Raphael Trenker, Deepti Rokkam, Andrew Morin, Priyanka Balasubrahmanyam, Verenice Paredes, Ivan Cheng, Rene de Waal Malefyt, Martin Oft, Patrick Lupardus, Sandro Vivona20-Gly 357, also called IL-18R2 and IL-18RAP) proteins purchased from Sino Biologicals (11102-H08H, 10176-H08H). For the primary immunization, llamas received recombinant IL-18Rα and recombinant IL-18Rβ emulsified

(2) Generation and engineering of potent single domain antibody-based bispecific IL-18 mimetics resistant to IL-18BP decoy receptor inhibitionmAbsJanuary 1, 2023Lipinski B, Unmuth L, Arras P, Becker S, Bauer C, Toleikis L, Krah S, Doerner A, Yanakieva D, Boje AS, et al.catalog number: 11102-H08H) and 250 nM (rh) his-tagged IL-18 Rβ ECD (Sino Biological, catalog number: 10176-H08H), respectively, for the first sorting round or separated (rh) IL-18 R subunits (250 nM) for the second

Human IL18RAP / IL1R7 Protein (His Tag)