Human IGF1R / CD221 Protein (His Tag) 10164-H08H from Sino Biological, Inc.

Product Specs
ItemHuman IGF1R / CD221 Protein (His Tag)
CompanySino Biological, Inc.
Price $348.00Supplier Page View Company Product Page
Catalog Number10164-H08H
Size100 µg
Conjugate/TagC-His
Purity> 90 % as determined by SDS-PAGE
Activity1.Immobilized Anti-IGF-1R (Research Grade Teprotumumab Biosimilar) at 2 µg/mL (100 µL/well) can bind Recombinant Human IGF1R / CD221 Protein (His Tag) (Cat: 10164-H08H), the EC50 is 1.2-3.6 ng/mL(QC tested). 2.Loaded Anti-IGF-1R (Research Grade Teprotumumab Biosimilar) on ProA Biosensor, can bind Recombinant Human IGF1R Protein, His Tag (Cat. No. 10164-H08H) with an affinity constant of 0.808nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested). 3.Recombinant Human IGF1R / CD221 Protein (His Tag) (Cat: 10164-H08H) captured on CM5 chip via Anti-His antibody, can bind Recombinant Human IGF1 Protein (Fc Tag) (Cat: 10598-H01H1) with an affinity constant of 36.400 nM as determined in an SPR assay (Biacore 8K) (Routinely tested). 4.Immobilized Recombinant Human IGF1R / CD221 Protein (His Tag) (Cat: 10164-H08H) at 5 µg/mL (100 µL/well) can bind Recombinant Human IGF1 Protein (Fc Tag) (Cat: 10598-H01H1), the EC50 is 85.9 ng/mL (Routinely tested)
FormatLyophilized from sterile PBS, pH 7.4
TypeRecombinant protein
Molecular WeightThe calculated molecular masses for α subunit, β subunit and the single chain of the receptor are approximately 81 kDa, 23 kDa and 104 kDa, respectively. As a result of glycosylation, the recombinant single chain, α subunit and β subunit have apparent molecular masses of approximately 150 kDa, 120 kDa and 48 kDa, respectively in SDS-PAGE under reducing conditions
SpeciesHuman
Molecule NameIGF1R
Source/Expression SystemHEK293 Cells
NCBI Full Gene Nameinsulin like growth factor 1 receptor
NCBI Gene AliasesCD221, IGFIR, IGFR, JTK13

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) Self-assembling peptide inspired by insulin and type 1 insulin-like growth factor for the treatment of androgenetic alopeciaBioactive materialsNovember 1, 2025Hu X, Guo L, Ding Y, Nie S, Fang J, Li J, Han Q, Ding D, Zhang Q, Wang T, et al.translational feasibility. 2 Materials and methods 2.1 Materials Recombinant human IGF-1R protein (10164-H08H) was purchased from Sino Biological Inc. Collagenase type I (C8140) and dihydrotestosterone (ID0310)

(2) ¹¹¹In- and ²²⁵Ac-Labeled Cixutumumab for Imaging and α-Particle Radiotherapy of IGF-1R Positive Triple-Negative Breast CancerMolecular pharmaceuticsDecember 2, 2019Solomon VR, Alizadeh E, Bernhard W, Hartimath SV, Hill W, Chekol R, Barreto KM, Geyer CR, Fonge H.

(3) Novel Monoclonal Antibody Is an Allosteric Insulin Receptor Antagonist That Induces Insulin ResistanceDiabetesJanuary 1, 2017Cieniewicz AM, Kirchner T, Hinke SA, Nanjunda R, D'Aquino K, Boayke K, Cooper PR, Perkinson R, Chiu ML, Jarantow S, et al.rat L6 skeletal muscle cells (ATCC CRL1458) as well as for the absence of binding to IGF-I receptor (10164-H08H; Sino Biological). Cieniewicz and Associates 207 IRAB-B Binding Afﬁnity Studies IRAB-B binding to

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Human IGF1R / CD221 Protein (His Tag)

Human IGF1R / CD221 Protein (His Tag) from Sino Biological, Inc.

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Sino Biological, Inc.

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Human IGF1R / CD221 Protein (His Tag) from Sino Biological, Inc.

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