Human CD47 Protein (ECD) 12283-HCCH from Sino Biological, Inc.

Product Specs
ItemHuman CD47 Protein (ECD)
CompanySino Biological, Inc.
Price $348.00Supplier Page View Company Product Page
Catalog Number12283-HCCH
Size100 µg
Conjugate/TagC-cleavage
Purity≥ 90 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC
ActivityMeasured by its ability to bind human SIRPA-His(Cat:11612-H08H）in functional ELISA. Measured by its ability to bind mouse SIRPA-His(Cat:50956-M08H）in functional ELISA
FormatLyophilized from sterile PBS, pH 7.4
TypeRecombinant protein
Molecular WeightThe recombinant human CD47 consists 128 amino acids and predicts a molecular mass of 14.5 kDa. The apparent molecular mass of the protein is approximately 35 kDa in SDS-PAGE under reducing conditions due to glycosylation
SpeciesHuman
Molecule NameCD47
Source/Expression SystemHEK293 Cells
NCBI Full Gene NameCD47 molecule
NCBI Gene AliasesIAP, MER6, OA3

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) Combining CD38 antibody with CD47 blockade is a promising strategy for treating hematologic malignancies expressing CD38Frontiers in ImmunologyJune 25, 2024Song Li, Dianze Chen, Yanan Yang, Huiqin Guo, Dandan Liu, Nana Sun, Xing Bai, Kaili Wang, Tengfei Li, Guanghui Li, et al.for 60 s in CD38 antigen (Kactus Biosystems, Cat# CD3-HM138) or CD47 antigen (Sino Biological, Cat# 12283-HCCH) wells (association step), and probe incubation was performed for 60 s in Q buffer (dissociation step).

(2) The antitumor activities of anti-CD47 antibodies require Fc-FcγR interactionsCancer CellDecember 1, 2023Juan C. Osorio, Patrick Smith, David A. Knorr, Jeffrey V. Ravetchwere determined by ELISA using recombinant mouse (SinoBiological 57231-MNAH) and human (SinoBiological 12283-HCCH) CD47, respectively. Blocking activity of 5F9-mIgG2a and 2D3-mIgG2a was determined by competitive ELISA

(3) The Antitumor Activities of Anti-CD47 Antibodies Require Fc-FcγR interactionsbioRxivJuly 5, 2023Juan C. Osorio, Patrick Smith, David A. Knorr, Jeffrey V. Ravetchwere determined by ELISA using recombinant mouse (SinoBiological 57231-MNAH) and human (SinoBiological 12283-HCCH) CD47, respectively. Blocking activity of 5F9-mIgG2a and 2D3-mIgG2a was determined by competitive ELISA

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Human CD47 Protein (ECD)

Human CD47 Protein (ECD) from Sino Biological, Inc.

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Sino Biological, Inc.

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Human CD47 Protein (ECD) from Sino Biological, Inc.

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