Human COMP Protein (His Tag) 10173-H08H from Sino Biological, Inc.

Product Specs
ItemHuman COMP Protein (His Tag)
CompanySino Biological, Inc.
Price $298.00Supplier Page View Company Product Page
Catalog Number10173-H08H
Size100 µg
Conjugate/TagC-His
Purity> 80 % as determined by SDS-PAGE
ActivityMeasured by its ability to induce adhesion of ATDC5 mouse chondrogenic cells.When cells are added to COMP-coated plates (0.625 µg/mL and 100 µL/well), approximately >30% cells will adhere specifically after 60 minutes at 37℃
FormatLyophilized from sterile PBS, pH 7.4
TypeRecombinant protein
Molecular WeightThe mature form of human COMP consists of 748 amino acids after removal of the signal peptide and predicts a molecular mass of 82.4 kDa. As a result of glycosylation, the apparent molecular mass of rhCOMP is approximately 120-130 kDa in SDS-PAGE under reducing conditions
SpeciesHuman
Molecule NameCOMP
Source/Expression SystemHEK293 Cells
NCBI Full Gene Namecartilage oligomeric matrix protein
NCBI Gene AliasesCTS2, EDM1, EPD1, MED, PSACH, THBS5, TSP-5, TSP5

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(1) Downregulation of NNMT affects trophoblast function via inhibiting COMP/CD36/ERK1/2 axis in recurrent spontaneous abortionCellular signallingAugust 1, 2025Huang J, Wan Z, Li J, Xiong X, Jiang R, Yang B, Xiong C, Chen H, Wan X, Luo Q, et al.

(2) Single-cell profiling of bone metastasis ecosystems from multiple cancer types reveals convergent and divergent mechanisms of bone colonizationCell GenomJuly 9, 2025Liu F, Ding Y, Xu Z, Hao X, Pan T, Miles G, Wang S, Wu YH, Liu J, Bado IL, et al.sRANKL,Peprotech,Cat#AF-310-01 recombinant human TWEAK,Sino Biological,Cat#90094-C04H recombinant human COMP,Sino Biological,Cat#10173-H08H recombinant human NRG1,Sino Biological,Cat#10658-H08H recombinant human SEMA4A,Sino Biological,Cat#11756-H08H-100 recombinant

(3) ADAMTS7 degrades Comp to fuel BMP2-dependent osteogenic differentiation and ameliorate oncogenic potential in osteosarcomasFEBS open bioSeptember 1, 2020Wang C, Chen Y, Xiang H, Wu X, Tang Q, Ma X, Zhang L.HaEmek, Israel) and incubated at 37 °C in a 5% CO2 humidified incubator. Recombinant human Comp (rComp; #10173‐H08H) was purchased from Sino Biological (Shanghai, China) and Noggin (#120‐10C) was obtained from PeproTech

Human COMP Protein (His Tag)