Human IL18R1 / CD218a Protein (ECD, His Tag) 11102-H08H from Sino Biological, Inc.

Product Specs
ItemHuman IL18R1 / CD218a Protein (ECD, His Tag)
CompanySino Biological, Inc.
Price $298.00Supplier Page View Company Product Page
Catalog Number11102-H08H
Conjugate/TagC-His
Purity≥ 95 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC
TypeRecombinant protein
Molecular WeightThe recombinant human IL18R1 comprises 322 amino acids with a predicted molecular mass of 37.2 kDa. As a result of glycosylation, the apparent molecular mass of rhIL18R1 is approximately 59.8 kDa in SDS-PAGE under reducing conditions
SpeciesHuman
Molecule NameIL18R1
Source/Expression SystemHEK293 Cells
NCBI Full Gene Nameinterleukin 18 receptor 1
NCBI Gene AliasesCD218a, CDw218a, IL-18R-alpha, IL-18Ralpha, IL-1Rrp, IL18RA, IL18Ralpha2, IL1RRP
FormatLyophilized from sterile PBS, pH 7.4
Activity1.Loaded Recombinant Human IL-18R beta / IL-18RAP Protein, hFc & AVI Tag (Cat. No. 10176-H41H-B) on ProA Biosensor, can bind Recombinant Human IL-18Rα Protein, His Tag (Cat. No. 11102-H08H) (Premixed with Human IL-18 Protein, Tag Free, Cat. No. 10119-HNCE) with an affinity constant of 7.7 nM as determined in BLI assay (Sartorius Octet RED384) (QC tested). 2.Recombinant Human IL-18R beta / IL-18RAP Protein, hFc Tag (Cat. No. 10176-H02H) captured on Protein A chip can bind Recombinant Human IL-18 Protein (Cat. No. 10119-HNCE) (Premixed with Recombinant Human IL-18Rα Protein, His Tag, Cat. No. 11102-H08H) with an affinity constant of 12.85 nM as determined in an SPR assay (Biacore T200) (Routinely tested)
Size100 µg

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) Structure-Guided Stapling of Dimeric Conformations and Linker Engineering Enhance Thermostability and Fine-Tune Activity of Bispecific VHH Cytokine AgonistsAntibodies (Basel)September 1, 2025Raphael Trenker, Deepti Rokkam, Andrew Morin, Priyanka Balasubrahmanyam, Verenice Paredes, Ivan Cheng, Rene de Waal Malefyt, Martin Oft, Patrick Lupardus, Sandro VivonaIL-18Rβ ECD (Phe 20-Gly 357, also called IL-18R2 and IL-18RAP) proteins purchased from Sino Biologicals (11102-H08H, 10176-H08H). For the primary immunization, llamas received recombinant IL-18Rα and recombinant IL-18Rβ

(2) Generation and engineering of potent single domain antibody-based bispecific IL-18 mimetics resistant to IL-18BP decoy receptor inhibitionmAbsJanuary 1, 2023Lipinski B, Unmuth L, Arras P, Becker S, Bauer C, Toleikis L, Krah S, Doerner A, Yanakieva D, Boje AS, et al.indirect immunofluorescence staining with 250 nM (rh) his-tagged IL-18 Rα (Sino Biological, catalog number: 11102-H08H) and 250 nM (rh) his-tagged IL-18 Rβ ECD (Sino Biological, catalog number: 10176-H08H), respectively,

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Human IL18R1 / CD218a Protein (ECD, His Tag)

Human IL18R1 / CD218a Protein (ECD, His Tag) from Sino Biological, Inc.

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Sino Biological, Inc.

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Human IL18R1 / CD218a Protein (ECD, His Tag) from Sino Biological, Inc.

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