Human Periostin / POSTN Protein (His Tag) 10299-H08H from Sino Biological, Inc.

Product Specs
ItemHuman Periostin / POSTN Protein (His Tag)
CompanySino Biological, Inc.
Price $298.00Supplier Page View Company Product Page
Catalog Number10299-H08H
Conjugate/TagC-His
Purity≥ 95 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC
TypeRecombinant protein
Molecular WeightThe recombinant human POSTN consists of 771 amino acids and has a predicted molecular mass of 86.4 kDa. In SDS-PAGE under reducing conditions, it migrates with an apparent molecular mass of 66-80 kDa due to glycosylation
SpeciesHuman
Molecule NamePOSTN
Source/Expression SystemHEK293 Cells
NCBI Full Gene Nameperiostin
NCBI Gene AliasesOSF-2, OSF2, PDLPOSTN, PN
ActivityMeasured by its ability to induce adhesion of ATDC5 mouse chondrogenic cells.When cells are added to POSTN-His coated plates (20µg/mL, 100µL/well), approximately >45% will adhere specifically after 30 minutes at 37℃
FormatLyophilized from sterile PBS, 5% Trehalose, pH 7.0
Size100 µg

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Email: marketing@sinobiological.com

(1) Fibroblast-derived POSTN promotes colorectal cancer progression under high-fat diet by reprogramming fatty acid metabolism in tumor cellCell Communication and SignalingJanuary 8, 2026Biao Li, Shasha Hou, Tian Tian, Shuai Yuan, Anrui Li, Yao Feng, Zhuoxi Liu, Jing Mi, Zhengyi Cheng, Shengnan Lv, et al.6-well plates and cultured for 12 h to allow cell adhesion. The recombinant protein POSTN (100 ng/mL, 10299-H08H, Sinobiological), AKT inhibitor LY294002 (20 µM, L832989-10 mg, Macklin), ERK inhibitor PD98059 (10µM,

(2) The impact of POSTN on tumor cell behavior and the tumor microenvironment in lung adenocarcinomaInternational immunopharmacologyJanuary 3, 2025Sun D, Lu J, Tian H, Li H, Chen X, Hua F, Yang W, Yu J, Chen D.

(3) A Role for Periostin Pathological Variants and Their Interaction with HSP70-1a in Promoting Pancreatic Cancer Progression and ChemoresistanceInternational journal of molecular sciencesDecember 8, 2024Tsunetoshi Y, Sanada F, Kanemoto Y, Shibata K, Masamune A, Taniyama Y, Yamamoto K, Morishita R.NJ, USA) was used as recombinant Pn 2, and recombinant human periostin protein HPLC-verified (cat. #10299-H08H, SinoBiological, Beijing, China) was used for recombinant Pn 4. The eluate was electrophoresed on a

(5) Periostin Exon-21 Antibody Neutralization of Triple-Negative Breast Cancer Cell-Derived Periostin Regulates Tumor-Associated Macrophage Polarization and AngiogenesisCancersOctober 11, 2021Fujikawa T, Sanada F, Taniyama Y, Shibata K, Katsuragi N, Koibuchi N, Akazawa K, Kanemoto Y, Kuroyanagi H, Shimazu K, et al.3548-F2–050) or periostin lacking exon 17 and 21 (Pn-4; SinoBiological, Chesterbrook, PA, USA, cat # 10299-H08H) were administered to the media, and cells (PBMCs, U937 and THP-1) were harvested after 24 hours for

(6) Periostin promotes liver fibrogenesis by activating lysyl oxidase in hepatic stellate cellsThe Journal of biological chemistryAugust 17, 2018Kumar P, Smith T, Raeman R, Chopyk DM, Brink H, Liu Y, Sulchek T, Anania FA.

(7) Periostin expression in intra-tumoral stromal cells is prognostic and predictive for colorectal carcinoma via creating a cancer-supportive nicheOncotargetJanuary 5, 2016Xu X, Chang W, Yuan J, Han X, Tan X, Ding Y, Luo Y, Cai H, Liu Y, Gao X, et al.cultured with 100% conditional media of colonic fibroblasts, complete medium with 100 ng/mL rhPOSTN (10299-H08H, Sino Biological, Beijing, China), and complete medium alone, respectively. PI3K/Akt kinase inhibitor,

Human Periostin / POSTN Protein (His Tag)