Human IL22 / IL-22 / Interleukin 22 Protein 13059-HNAE from Sino Biological, Inc.

Product Specs
ItemHuman IL22 / IL-22 / Interleukin 22 Protein
CompanySino Biological, Inc.
Price $178.00Supplier Page View Company Product Page
Catalog Number13059-HNAE
Conjugate/TagUnconjugated
Purity≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-MALS
TypeRecombinant protein
Molecular WeightThe recombinant human IL22 consists of 147 amino acids and predicts a molecular mass of 16.9 KDa. It migrates as an approximately 15 KDa band in SDS-PAGE under reducing conditions. The molecular weight of this protein is around 18.4 kDa verified by SEC-MALS
SpeciesHuman
Molecule NameIL22
Source/Expression SystemE. coli
NCBI Full Gene Nameinterleukin 22
NCBI Gene AliasesIL-21, IL-22, IL-D110, IL-TIF, ILTIF, TIFIL-23, TIFa, zcyto18
Activity1.Measured by its ability to induce IL-10 secretion in COLO 205 human colorectal adenocarcinoma cells. The ED50 for this effect is typically 0.3-1.2 ng/mL. 2.Human small intestinal organoids were cultured with IL22(Cat#13059-HNAE), FGF10(Cat#10573-HNAE), EGF(Cat#50482-MNCH), NOG(Cat#50688-M02H). (Routinely tested). Data provided by D1 Medical Technology
FormatLyophilized from sterile PBS, pH 8.0
Size20 µg

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) Elevated SNHG15 empowers keratinocytes hyperproliferation through activation of STAT3/Cyclin D1 axis in psoriasisActa Pharmaceutica Sinica BOctober 17, 2025Lipeng Tang, Guanzhuo Li, Jiameng Chang, Haiyan Xian, Yanjie Liu, Luping Lin, Zixin Dai, Zhenting Liu, Xinmin Qiu, Bowen Zhang, et al.RiboBio company (Guangzhou, China). IL-6 (10395-HNAE), IL-1β (10139-HNAE), TNF-α (10602-HNAE), IL-22 (13059-HNAE), and IL-17A (12047-HNAE) were acquired from Sino Biological Inc. (Beijing, China). IL-23 (PRP1909)

(2) Topical TYK2 inhibitor ameliorates psoriasis-like dermatitis via the AKT-SP1-NGFR-AP1 pathway in keratinocytesClinical and translational medicineMarch 1, 2025Fang Z, Jiang R, Wang Y, Chen W, Chen X, Yin M.experiments, KCs were treated with human IL‐17A (200 ng/mL, cat. 7955‐IL‐100/CF, R&D), IL‐22 (50 ng/mL, cat. 13059‐HNAE, Sino Biological) and TNF‐α (10 ng/mL, cat. 210‐TA‐005, R&D) for 48 h. Additionally, 100 ng/mL nerve

(3) S1PR3-driven positive feedback loop sustains STAT3 activation and keratinocyte hyperproliferation in psoriasisCell death & diseaseJanuary 20, 2025Lian P, Li L, Lu R, Zhang B, Wazir J, Gu C, Ma B, Pu W, Cao W, Huang Z, et al.Cells were treated with 25 μg/mL IL-6 (Sino Biological, 10395-HNAE) or 25 μg/mL IL-22 (Sino Biological, 13059-HNAE). Additional treatments included FTY720 (MedChemExpress, HY-12005), TY52156 (MedChemExpress, HY-19736),

(4) Epstein–Barr Virus BRRF1 Induces Butyrophilin 2A1 in Nasopharyngeal Carcinoma NPC43 Cells via the IL-22/JAK3-STAT3 PathwayInternational Journal of Molecular SciencesDecember 15, 2024Yue Liu, Ka Sin Lui, Zuodong Ye, Luo Chen, Allen Ka Loon Cheungvector was used. Sequencing was used to verify all constructs. The cytokine IL22 (10 ng/mL, Cat. No. 13059-HNAE, Sino Biological, Beijing, China) was used in certain experiments after transfection in some experiments. HEK293T

(5) Sulforaphane alleviates psoriasis by enhancing antioxidant defense through KEAP1-NRF2 Pathway activation and attenuating inflammatory signalingCell Death & DiseaseNovember 25, 2023Chujun Ma, Chaode Gu, Panpan Lian, Junaid Wazir, Renwei Lu, Binjia Ruan, Lulu Wei, Li Li, Wenyuan Pu, Ziqi Peng, et al.P/S) at 37 °C in a humidified incubator with 5% CO2. HaCaT cells were treated with IL-22 (25 mmol/L; 13059-HNAE, Sino Biological, China) or TNF-α (25 mmol/L; 10602-H01H, Sino Biological, China) for 30 min or 24 h

(6) Human S100A7 Induces Mature Interleukin1α Expression by RAGE-p38 MAPK-Calpain1 Pathway in PsoriasisPloS oneJanuary 1, 2017Lei H, Li X, Jing B, Xu H, Wu Y.human S100A7 (11141-RP02), soluble recombinant human S100A7 (11141-HNAE), IL17A (12047-HNAE), IL-22 (13059-HNAE), IL-33 (10368-HNAE), IL36γ (10124-HNAE) and TNFα (10602-HNAE) were purchased from Sino Biological Inc.

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Human IL22 / IL-22 / Interleukin 22 Protein

Human IL22 / IL-22 / Interleukin 22 Protein from Sino Biological, Inc.

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Sino Biological, Inc.

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Human IL22 / IL-22 / Interleukin 22 Protein from Sino Biological, Inc.

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