Human Progranulin Protein (His Tag) 10826-H08H from Sino Biological, Inc.

Product Specs
ItemHuman Progranulin Protein (His Tag)
CompanySino Biological, Inc.
Price $2,248.00Supplier Page View Company Product Page
Catalog Number10826-H08H
FormatLyophilized from sterile PBS, pH 7.4
Size1 mg
Source/Expression SystemHEK293 Cells
Molecule NameGRN
SpeciesHuman
Molecular WeightThe secreted recombinant human Progranulin comprises 587 amino acids with a predicted molecular mass of 63.2 kDa. As a result of glycosylation, rhGRN migrates as an approximately 93.3 kDa band in SDS-PAGE under reducing conditions
TypeRecombinant protein
Purity> 95 % as determined by SDS-PAGE
Conjugate/TagC-His

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) Single-cell analysis reveals a subpopulation of adipose progenitor cells that impairs glucose homeostasisNature CommunicationsJune 6, 2024Hongdong Wang, Yanhua Du, Shanshan Huang, Xitai Sun, Youqiong Ye, Haixiang Sun, Xuehui Chu, Xiaodong Shan, Yue Yuan, Lei Shen, et al.used: MDK (Sino Biological, 10247-HNAB), APP (Sino Biological, 10703-H02H), and GRN (Sino Biological, 10826-H08H). For the in vivo monocyte infiltration assay, 1×106 CD9+CD55low APCs from lean control subjects and

(2) Chickens with a Truncated Light Chain Transgene Express Single-Domain H Chain-Only AntibodiesJournal of immunology (Baltimore, Md. : 1950)June 1, 2024Leighton PA, Ching K, Reynolds K, Vuong CN, Zeng B, Zhang Y, Gupta A, Morales J, Rivera GS, Srivastava DB, et al.

(3) Common light chain chickens produce human antibodies of high affinity and broad epitope coverage for the engineering of bispecificsmAbsJanuary 1, 2021Ching KH, Berg K, Reynolds K, Pedersen D, Macias A, Abdiche YN, Harriman WD, Leighton PA.Animals were initially immunized intramuscularly with 200 μg recombinant human PGRN (Sino Biological, 10826-H08H) emulsified with 250 μL Freund’s Complete Adjuvant (Thermo Fisher, 77140). Two weeks later, animals

(4) Progranulin inhibits LPS-induced macrophage M1 polarization via NF-кB and MAPK pathwaysBMC immunologyJune 5, 2020Liu L, Guo H, Song A, Huang J, Zhang Y, Jin S, Li S, Zhang L, Yang C, Yang P.

(5) Expression of human lambda expands the repertoire of OmniChickensPloS oneJanuary 1, 2020Ching KH, Berg K, Morales J, Pedersen D, Harriman WD, Abdiche YN, Leighton PA.antigen-specific titer, ELISA plates were coated with 2 ug/mL human progranulin (Sino Biologicals, 10826-H08H) in PBS. Plates were blocked as described above, incubated with plasma at the indicated dilutions for

(6) Progranulin Promotes Regeneration of Inflammatory Periodontal Bone Defect in Rats via Anti-inflammation, Osteoclastogenic Inhibition, and Osteogenic PromotionInflammationFebruary 1, 2019Chen Q, Cai J, Li X, Song A, Guo H, Sun Q, Yang C, Yang P.

(7) CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive declineEMBO molecular medicineDecember 1, 2018Suárez-Calvet M, Capell A, Araque Caballero MÁ, Morenas-Rodríguez E, Fellerer K, Franzmeier N, Kleinberger G, Eren E, Deming Y, Piccio L, et al.Tween‐20 in PBS buffer (pH = 7.4). Recombinant human PGRN protein (His Tag PGRN—Sino Biological, cat. no. 10826‐H08H) was used as a standard (15.6–2,000 pg/ml). In brief, Streptavidin‐coated 96‐well plates were blocked

(8) Chickens with humanized immunoglobulin genes generate antibodies with high affinity and broad epitope coverage to conserved targetsmAbsJanuary 1, 2018Ching KH, Collarini EJ, Abdiche YN, Bedinger D, Pedersen D, Izquierdo S, Harriman R, Zhu L, Etches RJ, van de Lavoir MC, et al.as above. Protein and DNA immunizations Immunogens were: recombinant human PGRN (Sino Biologicals, 10826-H08H), human BDNF (Sino Biologicals, 50240-MNAS), bovine thrombin (Sigma, T4648), murine IL-13 (Peprotech,

(9) Tumor necrosis factor receptor 2/AKT and ERK signaling pathways contribute to the switch from fibroblasts to CAFs by progranulin in microenvironment of colorectal cancerOncotargetApril 18, 2017Wang L, Yang D, Tian J, Gao A, Shen Y, Ren X, Li X, Jiang G, Dong T.detect the effects of human recombinant PGRN (rPGRN) (Sino Biological Inc., Beijing, China; cat NO. 10826-H08H) on proliferation ability, CCD-18Co cells were pre-plated in 96-well plate at 2000 cells per well in

(10) Assessing kinetic and epitopic diversity across orthogonal monoclonal antibody generation platformsmAbsJanuary 1, 2016Abdiche YN, Harriman R, Deng X, Yeung YA, Miles A, Morishige W, Boustany L, Zhu L, Izquierdo SM, Harriman W.program, 2 birds were immunized with 75 µg recombinant hPGRN (R&D systems 2420-PG or Sino Biologicals 10826-H08H) bi-weekly for 5 boosts intramuscularly followed by a final boost, which was increased to 100 µg and

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Human Granulin / GRN / Progranulin Protein (His Tag)

Human Progranulin Protein (His Tag) from Sino Biological, Inc.

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Sino Biological, Inc.

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Human Progranulin Protein (His Tag) from Sino Biological, Inc.

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