Mouse IL6 / Interleukin-6 Protein 50136-MNAE from Sino Biological, Inc.

Product Specs
ItemMouse IL6 / Interleukin-6 Protein
CompanySino Biological, Inc.
Price $158.00Supplier Page View Company Product Page
Catalog Number50136-MNAE
Conjugate/TagUnconjugated
Purity> 90 % as determined by SDS-PAGE
TypeRecombinant protein
Molecular WeightThe recombinant mouse IL6 consists of 188 amino acids and predicts a molecular mass of 21.9 KDa. It migrates as an approximately 22 KDa band in SDS-PAGE under reducing conditions
SpeciesMouse
Molecule NameIL6
Source/Expression SystemE. coli
NCBI Full Gene Nameinterleukin 6
NCBI Gene AliasesIl-6
ActivityMeasured in a cell proliferation assay using T1165 mouse plasmacytoma cells. The ED50 for this effect is typically 0.1-0.8 ng/mL
FormatLyophilized from sterile 50mM HAc, pH3.0
Size20 µg

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) LDB1 represses fetal hemoglobin expression by enhancing BCL11A transcriptionRedox BiolFebruary 4, 2026Si-Won Park, Chang-Yong Choi, In-Byung Park, Seok-Jin Kang, Hyeon Jeong Lee, Ji-In Kim, Joonbeom Bae, Dongho Geum, Yong-Pil Cheon, Taehoon Chunrecombinant human FLT-3L (R&D systems 308-FK-025), and 20 ng/ml recombinant mouse IL-6 (Sino biological 50136-MNAE) [27]. After 16 h, transduction efficiency was evaluated by analyzing GFP-positive cells using the FACSVerse™.

(2) Secretogranin 2 binds LILRB4 resulting in immunosuppressionNature immunologySeptember 1, 2025Yang X, Huang R, Fang M, He Y, Xie J, Liu X, Zhang C, Lou Q, Deng M, Xiong W, et al.stimulated with 20 μg ml−1) human IL-6 (Sino Biological, 10395-HNAE) or mouse IL-6 (Sino Biological, 50136-MNAE) for the indicated times, respectively. The cells were washed twice with cold PBS, lysed in whole-cell lysis

(3) Sublingual Dripping Pill Formulation of Ganoderma amboinense Fruiting Body Extract Attenuates CCl4-Induced Liver Fibrosis via Multi-Pathway RegulationCurrent Issues in Molecular BiologyAugust 28, 2025Chin-Feng Liu, Chong-Ming Pan, Chun-Lin LeeDarmstadt, Germany). Serum levels of TNF-α and IL-6 were measured with ELISA kits (Cat. Nos. 50349-MNAE and 50136-MNAE; Sino Biological Inc., North Wales, PA, USA), and CTGF concentrations with the CTGF ELISA Kit (LS-G26584;

(4) TIGIT deficiency promotes autoreactive CD4+ T-cell responses through a metabolic‒epigenetic mechanism in autoimmune myositisNat CommunMay 15, 2025Yimei Lai, Shuang Wang, Tingting Ren, Jia Shi, Yichao Qian, Shuyi Wang, Mianjing Zhou, Ryu Watanabe, Mengyuan Li, Xinyuan Ruan, et al.μg/ml), TGFβ1 (2 ng/ml, Sino Biological, Cat# 80116-RNAH-5), IL-6 (40 ng/ml, Sino Biological, Cat# 50136-MNAE), IL-23 (30 ng/ml, NovoProtein, Cat# C03U), and IL-1β (20 ng/ml, Sino Biological, Cat# 50101-MNAE).

(5) COX-2 inhibition as a therapeutic strategy for bone loss in Staphylococcus aureus osteomyelitisMolecular medicine (Cambridge, Mass.)May 7, 2025Chen Y, Li C, Jia J, Jiang Y, Zhang P, Cheng C, Zhang G, Gao L, Yang X, Zhao J, et al.16000-044), 40 ng/mL murine GM‒CSF (Sinobiological, 51048-MNAH), 40 ng/mL murine IL‒6 (Sinobiological, 50136-MNAE) and 1% penicillin‒streptomycin solution (Gibco, 15140122) for 4 days. For neutrophil preparation, as

(6) Comparative Effects of Monascin and Monascinol Produced by Monascus pilosus SWM-008 on Pro-Inflammatory Factors and Histopathological Alterations in Liver and Kidney Tissues in a Streptozotocin–Nicotinamide-Induced Rat ModelJournal of FungiNovember 25, 2024Pei-Xin Yang, Ya-Wen Hsu, Tzu-Ming Pan, Chun-Lin LeeTNF-α standard protein (80045-RNAE), interleukin-6 (IL-6) antibody (80076-T16), IL-6 standard protein (50136-MNAE), interleukin-1β (IL-1β) antibody (80023-RP02), and IL-1β standard protein (50101-MNAE) were purchased

(7) IL6-STAT3-C/EBPβ-IL6 positive feedback loop in tumor-associated macrophages promotes the EMT and metastasis of lung adenocarcinomaJournal of Experimental & Clinical Cancer ResearchFebruary 29, 2024Zhengyang Hu, Qihai Sui, Xing Jin, Guangyao Shan, Yiwei Huang, Yanjun Yi, Dejun Zeng, Mengnan Zhao, Cheng Zhan, Qun Wang, et al.protein: (Sino Biological, 10395-HNAE, Beijing, China), recombinant mouse IL-6 protein: (Sino Biological, 50136-MNAE, Beijing, China), IL-6 neutralizing antibody: (Sino Biological, 10395-R508, Beijing, China), recombinant

(8) VISTA Deficiency Exacerbates the Development of Pulmonary Fibrosis by Promoting Th17 DifferentiationJournal of inflammation researchJanuary 1, 2024Xie H, Zhong X, Chen J, Wang S, Huang Y, Yang N.transforming growth factor beta 1 (TGF-β1) (2 ng/mL, PeproTech, #100-21-2), IL-6 (40 ng/mL, Sino Biological, #50136-MNAE), IL-1β (20 ng/mL, PeproTech, #211-11B-2), IL-23 (30 ng/mL, NovoProtein, #C03U), anti-mouse IFN-γ (5

(9) IL-1β Is an Androgen-Responsive Target in Macrophages for Immunotherapy of Prostate CancerAdvanced science (Weinheim, Baden-Wurttemberg, Germany)June 1, 2023Wang D, Cheng C, Chen X, Wang J, Liu K, Jing N, Xu P, Xi X, Sun Y, Ji Z, et al.containing 10% FBS, 20 ng mL−1 GM‐CSF (Sino biological, 51048‐MNAH) and 20 ng mL−1 IL‐6 (Sino biological, 50136‐MNAE) for 5 days to obtain bone marrow myeloid‐derived suppressor cells. ChIP‐seq and ChIP‐qPCR ChIP‐seq

(10) Evidence for a neuromuscular circuit involving hypothalamic interleukin-6 in the control of skeletal muscle metabolismScience advancesJuly 29, 2022Katashima CK, de Oliveira Micheletti T, Braga RR, Gaspar RS, Goeminne LJE, Moura-Assis A, Crisol BM, Brícola RS, Silva VRR, de Oliveira Ramos C, et al.microinjections Recombinant IL6 Intracerebroventricular IL6 mouse recombinant microinjection (200 ng) from Sino Biological (50136-MNAE) was performed between 5:00 and 6:00 p.m., as previously described (14). IL6 neutralizing antibody Animals

(11) IL-6 deletion decreased REV-ERBα protein and influenced autophagy and mitochondrial markers in the skeletal muscle after acute exerciseFrontiers in immunologyJanuary 1, 2022Pinto AP, Muñoz VR, da Rocha AL, Rovina RL, Ferrari GD, Alberici LC, Simabuco FM, Teixeira GR, Pauli JR, de Moura LP, et al.On the 5th day after differentiation, the cells were treated with recombinant mouse IL-6 (25 ng/mL, #50136-MNAE from Sino Biological Inc®) or SR9009 (5 µM, #11929 from Cayman®) for 24 h. Koliphor (#C5135 from Sigma®)

(12) The RNase MCPIP3 promotes skin inflammation by orchestrating myeloid cytokine responseNature communicationsJuly 2, 2021Liu B, Huang J, Ashraf A, Rahaman O, Lou J, Wang L, Cai P, Wen J, Anwaar S, Liu X, et al.injected with 100 µl vehicle (PBS) or 2ug/200 ng/20 ng/2 ng (in 100ul) of recombinant mouse IL-6 (Cat# 50136-MNAE, Sino Biological) for 4 days, starting from the day of IMQ application. Wound healing and septic shock Skin

(13) BMI1 regulates multiple myeloma-associated macrophage's pro-myeloma functionsCell death & diseaseMay 15, 2021Zhang D, Huang J, Wang F, Ding H, Cui Y, Yang Y, Xu J, Luo H, Gao Y, Pan L, et al.SHH (Cat No. 461-SH-025) was purchased from R&D Systems (MN, USA). Recombinant mouse IL-6 (Cat No. 50136-MNAE) was purchased from SinoBiological (Beijing, China). Animals Mice were housed and maintained in pathogen-free

(14) Axl Deficiency Promotes the Neuroinvasion of Japanese Encephalitis Virus by Enhancing IL-1α Production from Pyroptotic MacrophagesJournal of virologyAugust 17, 2020Wang ZY, Zhen ZD, Fan DY, Qin CF, Han DS, Zhou HN, Wang PG, An J.ng of a recombinant mouse IL-1α (50114-MNAE, Sino Biological) or 60 ng of a recombinant mouse IL-6 (50136-MNAE; Sino Biological) per mouse 30 min prior to i.p. injection with 104 PFU of JEV; then, a daily i.p. injection

(15) Notch signalling regulates steroidogenesis in mouse ovarian granulosa cellsReproduction, fertility, and developmentMay 1, 2019Wang Y, Lu E, Bao R, Xu P, Feng F, Wen W, Dong Q, Hu C, Xiao L, Tang M, et al.

(16) The anti-inflammatory NHE-06 restores antitumor immunity by targeting NF-κB/IL-6/STAT3 signaling in hepatocellular carcinomaBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapieJune 1, 2018Lu X, Wo G, Li B, Xu C, Wu J, Jiang C, Wei J.

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Mouse IL6 / Interleukin-6 Protein

Mouse IL6 / Interleukin-6 Protein from Sino Biological, Inc.

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Sino Biological, Inc.

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Mouse IL6 / Interleukin-6 Protein from Sino Biological, Inc.

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