Human CD47 Protein (ECD,Fc Tag) 12283-H02H from Sino Biological, Inc.

Product Specs
ItemHuman CD47 Protein (ECD,Fc Tag)
CompanySino Biological, Inc.
Price $298.00Supplier Page View Company Product Page
Catalog Number12283-H02H
Size100 µg
Conjugate/TagC-human IgG1-Fc
Purity≥ 95 % as determined by SDS-PAGE ≥ 90 % as determined by SEC-HPLC
Activity1.Immobilized mouse SIRPA-His (Cat:50956-M08H) at 10 µg/ml (100 µl/well) can bind human CD47-Fc, The EC50 of human CD47-Fc is 0.05-0.13 µg/ml(Routinely tested). 2.Immobilized human SIRPG-His (Cat:11828-H08H) at 10 µg/ml (100 µl/well) can bind human CD47-Fc, The EC50 of human CD47-Fc is 0.58-1.34 µg/ml(Routinely tested). 3.Immobilized Recombinant Human CD47 Protein (ECD,Fc Tag) (Cat: 12283-H02H) at 2 µg/mL (100 µL/well) can bind Recombinant Human SIRP alpha / CD172a Protein (ECD, His Tag) (Cat: 11612-H08H), the EC50 is 20-60 ng/mL (QC tested). 4.Loaded Recombinant Human CD47 Protein, hFc Tag (Cat. No. 12283-H02H) on proA Biosensor, can bind Recombinant Human SIRP alpha/SHPS-1 Protein, His Tag (Cat. No. 11612-H08H) with an affinity constant of 0.693 µM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested)
FormatLyophilized from sterile PBS, pH 7.4
TypeRecombinant protein
Molecular WeightThe recombinant human CD47/Fc is a disulfide-linked homodimer. The reduced monomer comprises 362 amino acids and has a predicted molecular mass of 40.7 kDa. The apparent molecular mass of the protein is approximately 48-60 kDa in SDS-PAGE under reducing conditions due to glycosylation
SpeciesHuman
Molecule NameCD47
Source/Expression SystemHEK293 Cells
NCBI Full Gene NameCD47 molecule
NCBI Gene AliasesIAP, MER6, OA3

Add to Compare List

Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) SIRPγ-CD47 Interaction Positively Regulates the Activation of Human T Cells in Situation of Chronic StimulationFrontiers in immunologyJanuary 1, 2021Dehmani S, Nerrière-Daguin V, Néel M, Elain-Duret N, Heslan JM, Belarif L, Mary C, Thepenier V, Biteau K, Poirier N, et al.protein,hSIRPα,SinoBiological,11612-H08H,Human, Recombinant protein,SIRPγ,SinoBiological,11828-H08H,Human, Recombinant protein,CD47,SinoBiological,12283-H02H,Human, Recombinant protein,CD47,"AcroBiosystems, Newark, DE, USA",CD7-H82F6,Human, Commercial kit,Pan

(2) CD40 Enhances Type I Interferon Responses Downstream of CD47 Blockade, Bridging Innate and Adaptive ImmunityCancer immunology researchFebruary 1, 2020de Silva S, Fromm G, Shuptrine CW, Johannes K, Patel A, Yoo KJ, Huang K, Schreiber TH.

Be the First to Write a Review!

Human CD47 Protein (ECD,Fc Tag)

Human CD47 Protein (ECD,Fc Tag) from Sino Biological, Inc.

Description

Sino Biological, Inc.

Citations (2)

Reviews

Human CD47 Protein (ECD,Fc Tag) from Sino Biological, Inc.

About Biocompare

Advertise with Us

Specialized Search Tools

Site Map