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Human CD80 / B7-1 Protein
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Human CD80 / B7-1 Protein
Human CD80 / B7-1 Protein
Human CD80 / B7-1 Protein from Sino Biological, Inc.
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Citations:
(2)
Figures:
(1)
Supplier Page
Supplier Page from
Sino Biological, Inc. for
Human CD80 / B7-1 Protein
Description
The mature form of human B7-1 (NP_005182.1) extracellular domain (Met 1-Asn 242) with five amini acids (DDDDK) at the C-terminus was expressed and purified
Product Specs
Company Info
Citations
Reviews
Product Specs
Item
Human CD80 / B7-1 Protein
Company
Sino Biological, Inc.
Price
$348.00
Supplier Page
View Company Product Page
Catalog Number
10698-HCCH
Conjugate/Tag
C-cleavage
Purity
> 85 % as determined by SDS-PAGE
Type
Recombinant protein
Molecular Weight
The mature recombinant human B7-1 consists of 214 amino acids and predicts a molecular mass of 25.5 kDa. As a result of glycosylation, rhB7-1 migrates as approximately 45 kDa band in SDS-PAGE
Species
Human
Molecule Name
CD80
Source/Expression System
HEK293 Cells
NCBI Full Gene Name
CD80 molecule
NCBI Gene Aliases
B7, B7-1, B7.1, BB1, CD28LG, CD28LG1, LAB7
Format
Lyophilized from sterile PBS, pH 7.4
Size
100 µg
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Sino Biological, Inc.
37 Industrial Blvd
Suite B
Paoli
,
PA
19301
United States
Phone
: 215-583-7898
Fax: 267-657-0217
Email: marketing@sinobiological.com
Company Profile
Website:
sinobiological.com
Citations (2)
(1)
FcγRIIB Is an Immune Checkpoint Limiting the Activity of Treg-Targeting Antibodies in the Tumor Microenvironment
Cancer immunology research
March 4, 2024
Knorr DA, Blanchard L, Leidner RS, Jensen SM, Meng R, Jones A, Ballesteros-Merino C, Bell RB, Baez M, Marino A,
et al
.
and
blocking activity
of
human
anti–CTLA-4 were determined by
ELISA
using recombinant human B7.1 (#
10698-HCCH
,
Sino Biological
), recombinant human CTLA-4 (#
11159-HNAH
,
Sino Biological
), and recombinant
human
FcγRs
(2)
FcyRIIB is a novel immune checkpoint in the tumor microenvironment limiting activity of Treg-targeting antibodies
bioRxiv
July 4, 2023
David Knorr, Rom Leidner, Shawn Jensen, Ryan Meng, Andrew Jones, Carmen Ballesteros-Merino, R. Bryan Bell, Maria Baez, David Sprott, Carlo Bifulco,
et al.
anti-CTLA-4 monoclonal antibodies were determined by
ELISA
using recombinant human B7.1 (
Sino Biological
, #
10698-HCCH
),
human
CTLA-4
(
Sino Biological
,
11159-HNAH
), and
human
FcyRs (
human
FCGR2A
#
10374-H08H
,
human
FCGR2B
<<
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Human CD80 / B7-1 Protein from Sino Biological, Inc.
Supplier Page
View Company Product Page
$348.00
Product Specs
Company Info
Citations
Reviews
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