Human TNFSF10 / TRAIL / APO-2L / CD253 Protein 10409-HNAE from Sino Biological, Inc.

Product Specs
ItemHuman TNFSF10 / TRAIL / APO-2L / CD253 Protein
CompanySino Biological, Inc.
Price $348.00Supplier Page View Company Product Page
Catalog Number10409-HNAE
Size100 µg
Conjugate/TagUnconjugated
Purity≥ 95 % as determined by SDS-PAGE
FormatLyophilized from sterile 50mM Tris, 300mM NaCl, pH 7.2
Activity1.Loaded Recombinant Human DR5/TRAIL R2 Protein, hFc Tag (Cat. No. 10465-H02H) on AHC Biosensor, can bind Recombinant Human TRAIL/TNFSF10 Protein (Cat. No. 10409-HNAE) with an affinity constant of 0.253 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested). 2.Loaded Recombinant Human Osteoprotegerin/TNFRSF11B Protein (hFc Tag) (Cat. No. 10271-H02B) on proA Biosensor, can bind Recombinant Human TRAIL/TNFSF10 Protein (Cat. No. 10409-HNAE) with an affinity constant of 2.390 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested)
TypeRecombinant protein
Molecular WeightThe recombinant human TNFSF10 consists of 169 amino acids and has a calculated molecular mass of 19.6 kDa. It migrates as an approximately 19 kDa band in SDS-PAGE under reducing conditions
SpeciesHuman
Molecule NameTNFSF10
Source/Expression SystemE. coli
NCBI Full Gene NameTNF superfamily member 10
NCBI Gene AliasesAPO2L, Apo-2L, CD253, TANCR, TL2, TNLG6A, TRAIL

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) Single-cell profiling of bone metastasis ecosystems from multiple cancer types reveals convergent and divergent mechanisms of bone colonizationCell GenomJuly 9, 2025Liu F, Ding Y, Xu Z, Hao X, Pan T, Miles G, Wang S, Wu YH, Liu J, Bado IL, et al.,Sino Biological,Cat#11756-H08H-100 recombinant human EFNA5,Sino Biological,Cat#10192-H08H-100 recombinant human TNFSF10,Sino Biological,Cat#10409-HNAE-100 recombinant human BMP8A,MedChemExpress,Cat#HY-P700031AF "Mouse anti-Human CD4, 1:100",ThermoFisher scientific

(2) Pomalidomide sensitizes lung cancer cells to TRAIL/CDDP-induced apoptosis via directly targeting electron transfer flavoprotein alpha subunitBioorganic chemistryDecember 1, 2024Li L, Huang Z, Huang Y, Li Y, Ma X, Li P, Du W, Wang H, Zhao Y, Zeng S, et al.

(3) PYCR1 regulates TRAIL‑resistance in non‑small cell lung cancer cells by regulating the redistribution of death receptorsOncology lettersMay 1, 2024You C, He J, Cao C, Sheng D, Wang L, Huang Z, Zhang X, Yi C, Sun Y, Huang Y.explored. Materials and methods Reagents and plasmids rhTRAIL was purchased from Sino Biological, Inc. (cat. no. 10409-HNAE). A negative control siRNA with no homology to other genes (‘NC’ hereafter) was used in RNA interference

(4) Blocking TRAIL-DR5 signaling pathway with soluble death receptor 5 fusion protein mitigates radiation-induced injuryFrontiers in PharmacologyMay 18, 2023Danyang Zhao, Lei Yang, Peng Han, Haihui Zhang, Fanjun Wang, Zhiyun Meng, Hui Gan, Zhuona Wu, Wenzhong Sun, Chuan Chen, et al.equipment The human TRAIL, mouse TRAIL and human DR5 proteins were purchased from Sino Biological Inc. (10409-HNAE, 50166-M07E, and 10465-H02H, Beijing, China) and sDR5-Fc was provided by Amshenn Inc. Biotinylation

(5) SIRT1 activation synergizes with FXR agonism in hepatoprotection via governing nucleocytoplasmic shuttling and degradation of FXRActa pharmaceutica Sinica. BFebruary 1, 2023Cui S, Hu H, Chen A, Cui M, Pan X, Zhang P, Wang G, Wang H, Hao H.A) was purchased from Peprotech. Recombinant human FasL (10,244-H07Y) and recombinant human TRAIL (10409-HNAE) were purchased from Sino Biological. Recombinant murine TNFα (14-8321-63) was purchased from Bioworld

(6) Tumor necrosis factor alpha delivers exogenous inflammation-related microRNAs to recipient cells with functional targeting capabilitiesMolecular therapy : the journal of the American Society of Gene TherapySeptember 7, 2022Zhao Y, Zhang T, Shen X, Huang A, Li H, Wang L, Liu X, Wang X, Song X, Wang S, et al.

(7) Preclinical studies of a death receptor 5 fusion protein that ameliorates acute liver failureJournal of molecular medicine (Berlin, Germany)September 1, 2019Chen Q, Wang P, Zhang Q, Xia M, Zhang G, Li J, Shen E, Chen YH, Wan X.

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Human TNFSF10 / TRAIL / APO-2L / CD253 Protein

Human TNFSF10 / TRAIL / APO-2L / CD253 Protein from Sino Biological, Inc.

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Sino Biological, Inc.

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Human TNFSF10 / TRAIL / APO-2L / CD253 Protein from Sino Biological, Inc.

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