Human CD80 / B7-1 Protein (His Tag) 10698-H08H from Sino Biological, Inc.

Product Specs
ItemHuman CD80 / B7-1 Protein (His Tag)
CompanySino Biological, Inc.
Price $198.00Supplier Page View Company Product Page
Catalog Number10698-H08H
Size100 µg
Conjugate/TagC-His
Purity≥ 95 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC
Activity1.Immobilized B7-1 Protein, Human, Recombinant (His Tag) (Cat: 10698-H08H) at 2 µg/ml (100 µl/well) can bind CTLA-4 Protein, Human, Recombinant (His & hFc Tag) (Cat: 11159-H03H). The EC50 of of CTLA-4 (His & hFc Tag) (Cat: 11159-H03H) is 35-80 ng/ml(Routinely tested). 2.Loaded Recombinant Human CTLA4 / CD152 Protein (Fc Tag) (Cat: 11159-H02H6) on ProA Biosensor, can bind Recombinant Human CD80 / B7-1 Protein (His Tag) (Cat: 10698-H08H) with an affinity constant of 210 nM as determined in BLI assay (Sartorius Octet RED384) (Routinely tested). 3.Loaded Recombinant Human B7-1 Protein, His Tag(Cat. No. 10698-H08H) on His1K Biosensor, can bind Recombinant Human CD28 Protein, hFc Tag (Cat. No. 11524-H02H) with an affinity constant of 0.46 µM as determined in BLI assay (Sartorius Octet RED384) (QC tested) (Routinely tested). 4.Immobilized Recombinant Human CD80 / B7-1 Protein (His Tag) (Cat: 10698-H08H) at 1 µg/mL (100 µL/well) can bind Anti-CD80(Research Grade Galix*mab Biosimilar), the EC50 is 1.2 ng/mL (Routinely tested). 5.Immobilized Recombinant Human CTLA4 / CD152 Protein (Fc Tag) (Cat: 11159-H02H6) at 10 µg/mL (100 µL/well) can bind Recombinant Human CD80 / B7-1 Protein (His Tag) (Cat: 10698-H08H), the EC50 is 0.2-1 µg/mL (QC tested). 6.Recombinant Cynomolgus CD28 / TP44 Protein (Fc Tag, ECD) (Cat: 90182-C02H) immobilized on CM5 chip, can bind Recombinant Human CD80 / B7-1 Protein (His Tag) (Cat: 10698-H08H) with an affinity constant of 10.500 µM as determined in an SPR assay (Biacore 8K) (Routinely tested)
FormatLyophilized from sterile PBS, pH 7.4
TypeRecombinant protein
Molecular WeightThe recombinant human B7-1 consists of 219 amino acids and has a predicted molecular mass of 25.4 kDa. By reduced SDS-PAGE, the apparent molecular mass of rh B7-1 is approximately 45-48 kDa due to glycosylation
SpeciesHuman
Molecule NameCD80
Source/Expression SystemHEK293 Cells
NCBI Full Gene NameCD80 molecule
NCBI Gene AliasesB7, B7-1, B7.1, BB1, CD28LG, CD28LG1, LAB7

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Sino Biological, Inc.

37 Industrial Blvd

Suite B

Paoli, PA 19301

United States

Phone: 215-583-7898
Fax: 267-657-0217

Email: marketing@sinobiological.com

Company Profile

Website: sinobiological.com

(1) Phase separation of chimeric antigen receptor promotes immunological synapse maturation and persistent cytotoxicityImmunityDecember 10, 2024Xu X, Chen H, Ren Z, Xu X, Wu W, Yang H, Wang J, Zhang Y, Zhou Q, Li H, et al.

(2) A functional antibody cross-reactive to both human and murine cytotoxic T-lymphocyte-associated protein 4 via binding to an N-glycosylation epitopemAbsJanuary 1, 2020Li D, Li J, Chu H, Wang Z.negative control antibodies were pre-mixed with 0.25 μg/mL of hCD80-His tag (Sino Biological, Cat: 10698-H08H) or hCD86-His tag (Sino Biological, Cat: 10699-H08H), or 0.5 μg/ml of mCD80-His tag (Sino Biological,

(3) PD-L1:CD80 Cis-Heterodimer Triggers the Co-stimulatory Receptor CD28 While Repressing the Inhibitory PD-1 and CTLA-4 PathwaysImmunityDecember 17, 2019Zhao Y, Lee CK, Lin CH, Gassen RB, Xu X, Huang Z, Xiao C, Bonorino C, Lu LF, Bui JD, et al.9049-B7 EZ-Link NHS-LC-Biotin,Thermo Fisher Scientific,Cat #21335 Human CD80-His,Sino Biological,Cat# 10698-H08H Human CD86-His,Sino Biological,Cat# 10699-H08H Human PD-1-huFc,ACROBiosystems,Cat # PD1-H5257 Human

(4) The utility of urinary CD80 as a diagnostic marker in patients with renal diseasesScientific reportsNovember 23, 2018Minamikawa S, Nozu K, Maeta S, Yamamura T, Nakanishi K, Fujimura J, Horinouchi T, Nagano C, Sakakibara N, Nagase H, et al.our ELISA. We produced a standard curve for CD80 with commercially quantified CD80 protein (Cat. No. 10698-H08H, Sino Biological Inc.) (Supplemental Fig. 1). In addition, we also produced a standard curve with an

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Human CD80 / B7-1 Protein (His Tag)

Human CD80 / B7-1 Protein (His Tag) from Sino Biological, Inc.

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Sino Biological, Inc.

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Human CD80 / B7-1 Protein (His Tag) from Sino Biological, Inc.

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